A LONGITUDINAL STUDY OF SUBSTANCE ABUSE AND HIV RISK AMONG ADULT LATINA MOTHER-DA

成年拉丁裔母亲药物滥用和艾滋病毒风险的纵向研究

• 批准号: 8228184
• 负责人: Mario R De La Rosa
• 金额: $ 35.56万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-03 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8228184
• 关键词: AIDS prevention; AIDS/HIV problem; Accounting; Acculturation; Adolescent; Adopted; Adult; Affect; Age; Alcohol or Other Drugs use; American; Anger; Buffers; Censuses; Centers for Disease Control and Prevention (U.S.); Chronic stress; Communication; Communities; County; Criminal Justice; Cross-Sectional Studies; Data; Data Collection; Daughter; Development; Doctor of Philosophy; Dominican; Drug usage; Employment; Environment; Equilibrium; Exhibits; Funding; Goals; HIV; Health; Hispanics; Homelessness; Honduran; Illicit Drugs; Imprisonment; Incidence; Individual; Institution; Laboratories; Latina; Latino; Learning; Link; Literature; Longevity; Longitudinal Studies; Maintenance; Medical; Mental Health; Methodology; Methods; Mexican; Minority Groups; Modeling; Mothers; National Institute of Drug Abuse; Outcome; Participant; Pilot Projects; Population; Population Growth; Prevention; Prevention program; Prevention strategy; Process; Public Health; Puerto Rican; Religion and Spirituality; Reporting; Research; Research Design; Risk; Risk Behaviors; Role; Rosa; Sampling; Substance Use Disorder; Substance abuse problem; System; Teenagers; Testing; Time; Trust; United States; United States National Institutes of Health; United States Substance Abuse and Mental Health Services Administration; Variant; Woman; Work; aged; base; experience; follow-up; health disparity; innovation; intergenerational; intimate partner violence; longitudinal design; prevent; programs; psychologic; social; socioeconomics; substance abuse prevention; success; theories; treatment program

DESCRIPTION (provided by the applicant): The HIV contraction rate for Latina women in the U.S. is six times the rate for non-Latina, White women. Latinas are suffering disparate negative consequences from substance use disorders, including intimate partner violence, incarceration, homelessness, and medical ailments. Our long-term goal is to reduce the incidence of HIV and substance abuse related health disparities among Latinas. The objective of this application, which is a significant step in pursuit of this goal, is to determine how substance use (both licit and illicit) and HIV risk behavior trajectories of a community-based sample of Latina mothers and daughters are influenced by changes in familial mechanisms (mother-daughter acoplamiento or attachment), cultural processes, and other social determinants of substance abuse and HIV risk behaviors over time. The study design involves four waves of data collection. Baseline data were collected in a cross-sectional pilot study of intergenerational drug use and HIV risk behaviors among Latina mothers and daughters funded by NIDA (R24DA014260, PI: Mario De La Rosa, Ph.D.). Three new longitudinal assessments are proposed to follow-up on baseline assessment. The first new follow-up assessment will be spaced approximately 5 years from the original study's baseline assessment. The remaining two follow-up assessments will occur 1 year from the preceding follow-up assessment. Our first aim is to determine the influence of cultural and social determinants on trajectories of change for substance use and HIV risk behaviors among a community-based sample of Latina mothers and daughters. The working hypothesis is that Latina mothers and daughters who experience (1) more acculturation to U.S. culture; (2) poorer socioeconomic conditions; (3) a loss of interpersonal supports; (4) less religious involvement; (5) involvement with the criminal justice system; (6) intimate partner violence; (7) greater employment, relationship, and/or residential related chronic stress; or (8) declining mental health and medical status since their baseline assessment will exhibit either an increase in or maintenance of high rates of substance use and HIV risk behaviors over the 7 year assessment time period. Our second aim is to determine the influence of mother-daughter attachment on trajectories of change for substance use and HIV risk behaviors. Latina mothers and daughters who either increase their levels of attachment or maintain consistently high levels of attachment will report reduced or consistently lower levels of substance use and HIV risk behaviors over a 7 year time period. Our third aim is to determine the moderating role of mother-daughter attachment on associations between experiences of detrimental social determinants and trajectories of change for substance use and HIV risk behaviors.

描述（由申请人提供）：美国拉丁裔妇女的HIV收缩率是非拉丁裔白人妇女的六倍。拉丁裔正在遭受药物使用障碍的不同负面后果，包括亲密的伴侣暴力，监禁，无家可归和医疗疾病。我们的长期目标是减少拉丁裔艾滋病毒和药物滥用与健康差异的发生率。这项应用的目标是追求这一目标的重要一步，是确定一种基于社区的拉丁裔母亲和女儿样本的物质使用（合法和非法）和艾滋病毒风险行为轨迹如何受到家庭机制的变化（母女伴侣或依恋）的变化（母女的依恋或依恋），文化过程，其他社会确定性滥用行为和HIV行为。研究设计涉及四波数据收集。基线数据是在由NIDA资助的拉丁裔母亲和女儿中的代际药物使用和艾滋病毒风险行为的横断面试点研究中收集的（R24DA014260，PI：Mario de la Rosa，Ph.D。）。提出了三项新的纵向评估，以进行基线评估。第一个新的随访评估将距离原始研究的基线评估约5年。其余的两次随访评估将从前面的随访评估中进行1年。我们的第一个目的是确定文化和社会决定因素对基于社区的拉丁裔母亲和女儿样本中毒品使用和艾滋病毒风险行为的变化轨迹的影响。工作假设是，经历（1）对美国文化的更适应的拉丁裔母亲和女儿； （2）社会经济状况较差； （3）丧失人际关系支持； （4）减少宗教参与； （5）参与刑事司法系统； （6）亲密伴侣暴力； （7）更多的就业，关系和/或与住宅相关的慢性压力；或（8）由于他们的基线评估将在7年评估期内表现出高度使用率和艾滋病毒风险行为的高度增加或维持高率的心理健康和医疗状况。我们的第二个目的是确定母女依恋对使用物质使用和艾滋病毒风险行为的变化轨迹的影响。拉丁裔母亲和女儿在7年的时间段内报告说，增加其依恋水平或保持一致的高度依恋水平将报告降低或持续降低药物使用水平和HIV风险行为。我们的第三个目的是确定母女依恋在有害的社会决定因素的经验与毒品使用变化轨迹和艾滋病毒风险行为之间的关联之间的关联。