Predoctoral Training in Bioinformatics and Computational Biology

生物信息学和计算生物学博士前培训

• 批准号: 8268050
• 负责人: THOMAS D TULLIUS
• 金额: $ 17.86万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8268050
• 关键词: Bioinformatics; Computational Biology; Training; pre-doctoral

DESCRIPTION (provided by applicant): This new application seeks support for the Predoctoral Training Program in Bioinformatics/Computational Biology at Boston University. The Bioinformatics Program aims to prepare top researchers for careers in the molecular life sciences who will support the advances now underway in modern medicine. Based largely on the framework of the human genome sequence, these advances depend upon a battery of high-throughput techniques that generate enormous quantities of data that in turn reflect the complexities of biological networks. Full exploitation of this information requires computation-based, interdisciplinary efforts. The Program will inculcate the skills required in this new environment, including (a) an understanding of basic biological systems, (b) facility with computational methods and statistics, especially for network analysis, and (c) the ability to interact and communicate with colleagues from diverse disciplines. The curriculum includes a strong foundation in computational methods and database development, along with in-depth discussions of relevant biological systems. Program features include (1) an annual International Workshop in Bioinformatics and Systems Biology, a joint undertaking of computational biology graduate training programs in Boston, Kyoto/Tokyo, and Berlin; (2) the Challenge Project, which offers teams of first-year trainees the opportunity to do original research on large-scale problems; (3) the Wet-Lab Experience, which introduces new trainees to state-of-the-art experimental methods in the summer before they officially enter the program; (4) the annual Student-Organized Symposium; and (5) three 9-week rotations. A distinguished training faculty of 31 members is drawn from 15 departments in five schools and colleges at Boston University. Areas of research include genomics, biological networks, statistical methods in bioinformatics, evolutionary genomics, metabolomics, and structural biology and bioinformatics. Several mentors are engaged in translational application of bioinformatics. Co-advising of trainees, by computational and experimental mentors, is strongly encouraged. Students play a large role in defining their research projects. 62 trainees currently are working towards the Ph.D. Six Predoctoral training slots per year are requested, which will support trainees for the first year o residence.

描述（由申请人提供）：这个新的应用程序寻求在生物信息学/计算生物学博士前培训计划在波士顿大学的支持。生物信息学计划旨在为分子生命科学的职业生涯做好准备，这些研究人员将支持现代医学正在进行的进步。这些进展主要基于人类基因组序列的框架，依赖于一系列高通量技术，这些技术产生了大量的数据，这些数据反过来反映了生物网络的复杂性。充分利用这些信息需要基于计算的跨学科努力。该计划将灌输在这个新的环境中所需的技能，包括（a）基本生物系统的理解，（B）设施与计算方法和统计，特别是网络分析，以及（c）互动和沟通的能力与来自不同学科的同事。课程包括计算方法和数据库开发的坚实基础，沿着相关生物系统的深入讨论。计划的特点包括：（1）生物信息学和系统生物学的年度国际研讨会，在波士顿，京都/东京和柏林的计算生物学研究生培训计划的联合事业;（2）挑战项目，为第一年的学员提供对大规模问题进行原创性研究的机会;（3）湿实验室的经验，它介绍了新的学员国家的最先进的实验方法在夏天之前，他们正式进入程序;（4）每年的学生组织的研讨会;和（5）三个9周的轮换。一个杰出的培训教师31名成员来自15个部门在五所学校和学院在波士顿大学。研究领域包括基因组学、生物网络、生物信息学中的统计方法、进化基因组学、代谢组学、结构生物学和生物信息学。几位导师从事生物信息学的翻译应用。强烈鼓励计算和实验导师为学员提供共同建议。学生在确定他们的研究项目中发挥着重要作用。目前有62名学员正在攻读博士学位。每年要求六个博士前培训名额，这将支持学员第一年居住。