Immunology & Pathogenesis Program Training Grant

描述（由申请人提供）：本申请为免疫学和发病机制（IMP）培训项目，旨在支持10位领域领先的科学家的培训活动，他们的研究中心是免疫生物学，教师都是分子和细胞生物学（MCB）部门的成员，每个人都有充足的研究支持和强有力的指导承诺。培训计划以MCB免疫学和发病机制部门为中心，大多数培训教师都是该部门的成员。IMP培训计划将侧重于感染，癌症和免疫病理背景下的基本免疫学机制。我们有一个共同的信念，即对免疫系统细胞的识别、激活、调节、分化和相互作用有一个彻底的、基本的了解，这将导致传染病、癌症和其他疾病的治疗，培训年轻的研究人员在这种方法上，同时提供基础分子和细胞生物学的广泛培训，为提高这一努力的成功提供了最有效的途径。MCB系和培训教师有一个长期的、明确的培训原则：早期、持续地强调学生和博士后的培训，为个人指导的创新研究之路。该项目致力于招募和培养来自不同个人背景的学生和博士后。IMP计划将为免疫学和发病机制的学员提供一个家，并为培训相关活动提供支持。拟资助研究生3名，博士后3名。研究生通常会在第二年开始获得支持，以确保对研究领域的投入，并提供额外的信息，以评估他们对项目做出特殊贡献的能力。博士后培训生一般在第一年或第二年开始获得资助。一般而言，受训人员将获得为期两年的培训补助金，其中包括

DESCRIPTION (provided by applicant): This application for a training program in Immunology and Pathogenesis (IMP) is designed to support the training activities of ten field-leading scientists whose research centers on immunobiology, the faculty members are all members of the Department of Molecular and Cell Biology (MCB), and each has ample research support and a strong commitment to mentoring. The training program is centered in the MCB Division of Immunology and Pathogenesis, in which most training faculty are members. The IMP Training program will focus on basic immunological mechanisms in the context of infections, cancer and immunopathology. We are motivated by the shared belief that achieving a thorough, basic understanding of recognition, activation, regulation, differentiation and interactions of cells of he immune system will lead to therapies for infectious disease, cancer and other ailments, and that training young investigators in this approach, while providing broad training in basic molecular and cell biology, offers a most productive avenue for enhancing success in this endeavor. The MCB Department and the training faculty have a long-standing and defining principle for training: early, persistent emphasis on student and postdoc training for an individually directed path to innovative research. The program is strongly committed to recruiting and training students and postdocs from diverse personal backgrounds. The IMP program will provide a home for trainees in Immunology and Pathogenesis and support for training related activities. We propose support for 3 graduate students and 3 postdoctoral fellows. Graduate students will generally be supported starting in their second year to ensure commitment to the research area and to provide additional information to evaluate their capability of providing exceptional contributions to the program. Postdoctoral trainees will generally be supported starting in their first or second year. In general trainees will be supported for 2 years on the training grant, with additional years supported from other sources. The training grant is designed to be the successor of an NCI-supported training grant (Molecular Immunology and Tumor Biology Training Program, T32 CA009179), which supported immunology research at Berkeley for 35 years. Due to the evolution of the research programs and new recruitments to the Division, the focus of that training grant solely on cancer has become increasingly restrictive. We therefore concluded that an NIAID-supported training grant focused more broadly on immunobiology research is a much better fit for our group. Consequently we are applying for this new training grant rather than for a renewal of T32 CA009179. PUBLIC HEALTH RELEVANCE: The relevance of immunology research to advances in public health has never before been so strong. This predoctoral and postdoctoral training program is committed to inculcating detailed understanding of the immune system as well as broad knowledge of molecular and cell biology and the principles of rigorous, elegant experimentation, in a manner that fosters innovative and inspirational contributions by the next generation of immuno-biologists.