Immunology & Pathogenesis Program Training Grant

描述(由申请人提供)：本申请为免疫学和病理学(IMP)培训计划，旨在支持十位领域领先的科学家的培训活动，他们的研究中心是免疫生物学，教职员工都是分子和细胞生物学(MCB)系的成员，每个人都有充足的研究支持和强烈的指导承诺。培训计划的中心是MCB免疫学和病理学部门，大多数培训教师都是该部门的成员。IMP培训计划将侧重于感染、癌症和免疫病理学背景下的基本免疫学机制。我们的共同信念是，彻底、基本地了解免疫系统细胞的识别、激活、调节、分化和相互作用将导致对传染病、癌症和其他疾病的治疗，培训年轻的研究人员在提供基础分子和细胞生物学方面的广泛培训的同时，为提高这一努力的成功提供了一条最有成效的途径。MCB部门和培训人员有一个长期和明确的培训原则：早期、持续地强调学生和博士后培训，以个人指导的方式进行创新研究。该项目致力于招收和培养来自不同个人背景的学生和博士后。IMP计划将为免疫学和病理学方面的受训者提供一个家，并为培训相关活动提供支持。我们建议支持3名研究生和3名博士后研究员。研究生一般会从二年级开始获得资助，以确保他们对研究领域的承诺，并提供更多信息来评估他们为该项目做出特殊贡献的能力。博士后实习生一般从第一年或第二年开始得到支持。一般而言，受训人员将获得为期2年的培训补助金支持， 其他来源支持的额外年份。该培训补助金旨在成为NCI支持的培训补助金(分子免疫学和肿瘤生物学培训计划，T32 CA009179)的继任者，该培训补助金为伯克利的免疫学研究提供了35年的支持。由于研究计划的演变和该司的新招聘，仅针对癌症的培训拨款的重点已变得越来越严格。因此，我们得出结论，由NIAID支持的更广泛地专注于免疫生物学研究的培训拨款更适合我们的团队。因此，我们申请的是这一新的培训补助金，而不是T32 CA009179的续期。

DESCRIPTION (provided by applicant): This application for a training program in Immunology and Pathogenesis (IMP) is designed to support the training activities of ten field-leading scientists whose research centers on immunobiology, the faculty members are all members of the Department of Molecular and Cell Biology (MCB), and each has ample research support and a strong commitment to mentoring. The training program is centered in the MCB Division of Immunology and Pathogenesis, in which most training faculty are members. The IMP Training program will focus on basic immunological mechanisms in the context of infections, cancer and immunopathology. We are motivated by the shared belief that achieving a thorough, basic understanding of recognition, activation, regulation, differentiation and interactions of cells of he immune system will lead to therapies for infectious disease, cancer and other ailments, and that training young investigators in this approach, while providing broad training in basic molecular and cell biology, offers a most productive avenue for enhancing success in this endeavor. The MCB Department and the training faculty have a long-standing and defining principle for training: early, persistent emphasis on student and postdoc training for an individually directed path to innovative research. The program is strongly committed to recruiting and training students and postdocs from diverse personal backgrounds. The IMP program will provide a home for trainees in Immunology and Pathogenesis and support for training related activities. We propose support for 3 graduate students and 3 postdoctoral fellows. Graduate students will generally be supported starting in their second year to ensure commitment to the research area and to provide additional information to evaluate their capability of providing exceptional contributions to the program. Postdoctoral trainees will generally be supported starting in their first or second year. In general trainees will be supported for 2 years on the training grant, with additional years supported from other sources. The training grant is designed to be the successor of an NCI-supported training grant (Molecular Immunology and Tumor Biology Training Program, T32 CA009179), which supported immunology research at Berkeley for 35 years. Due to the evolution of the research programs and new recruitments to the Division, the focus of that training grant solely on cancer has become increasingly restrictive. We therefore concluded that an NIAID-supported training grant focused more broadly on immunobiology research is a much better fit for our group. Consequently we are applying for this new training grant rather than for a renewal of T32 CA009179.