Functional Reorganization of Finger Movements to Improve Hand Dexterity

手指运动的功能重组以提高手的灵活性

• 批准号: 8385003
• 负责人: Rajiv Ranganathan
• 金额: $ 7.55万
• 依托单位: REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-05 至 2014-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8385003
• 关键词: Activities of Daily Living; Affect; Area; Automobile Driving; Behavior; Brain; Chronic; Clinical; Complex; Computers; Cues; Data; Effectiveness; Exercise; Fingers; Frequencies; Goals; Hand; Hand functions; Individual; Individuation; Instruction; Joints; Learning; Location; Maps; Motion; Motor; Movement; Participant; Patients; Pattern; Persons; Play; Positioning Attribute; Posture; Process; Protocols documentation; Rehabilitation therapy; Role; Signal Transduction; Simulate; Stimulus; Stroke; System; Techniques; Testing; Time; Training; Upper Extremity; Variant; arm; chronic stroke; design; experience; grasp; improved; innovation; insight; motor deficit; novel; novel strategies; research study; response; sensor; tool

DESCRIPTION (provided by applicant): The current proposal aims to facilitate hand function in chronic stroke patients. Deficits in hand function are extremely common after stroke and persist for a prolonged period of time. While conventional techniques have emphasized the repetitive practice of simple movements, the role of coordination in rehabilitation has not been explored extensively. In this proposal, the PIs examine the influence of training novel finger coordination patterns as a means of improving hand function and dexterity. They propose an innovative protocol to induce the reorganization of finger movements. Instead of providing explicit instructions, the PIs will elicit different coordination patterns in the context of a simpe task. Participants wear a data glove and the signals from the glove are mapped on to the position of a computer cursor. The goal of the participants is to move their fingers so that they learn to move the computer cursor to different targets on a screen. This protocol has the advantage of reducing the complex task of finger coordination into the simpler task of planning cursor movements. The first aim investigates how changing the relation between finger and cursor motion (i.e., changing the map) affects the reorganization of finger coordination. Specifically, the PIs examine the effectiveness of changing two features of the map (gain and variability) in driving the participants to reorganize their finger movements. The second aim examines the feasibility of using this protocol to improve hand function and dexterity in chronic stroke patients. Patients undergo training in the glove task with different maps designed to elicit varied finger movements. Clinical tests are then used to determine if training resulted in improved hand function. The results of these experiments have the potential to transform rehabilitation approaches by introducing the exploration of novel coordination patterns as an important component of training protocols. PUBLIC HEALTH RELEVANCE: Deficits in hand motor function are extremely common after stroke. The current proposal aims to improve hand function in chronic stroke patients by facilitating the practice of novel finger coordination patterns.

描述（由申请人提供）：当前提案旨在促进慢性中风患者的手部功能。中风后手部功能缺陷极为常见，并且会持续很长一段时间。虽然传统技术强调简单动作的重复练习，但协调在康复中的作用尚未得到广泛探索。在该提案中，PI 检查了训练新颖的手指协调模式作为改善手部功能和灵活性的手段的影响。他们提出了一种创新方案来诱导手指运动的重组。 PI 不会提供明确的指令，而是会在简单任务的上下文中引发不同的协调模式。参与者戴着数据手套，来自手套的信号被映射到计算机光标的位置。参与者的目标是移动手指，以便学习将计算机光标移动到屏幕上的不同目标。该协议的优点是可以将手指协调的复杂任务简化为规划光标移动的简单任务。第一个目标是研究改变手指和光标运动之间的关系（即改变地图）如何影响手指协调的重组。具体来说，PI 检查改变地图的两个特征（增益和变异性）在驱动参与者重新组织手指运动方面的有效性。第二个目标是检查使用该方案来改善慢性中风患者手部功能和灵活性的可行性。患者接受手套任务训练，使用不同的地图来诱导 各种手指动作。然后使用临床测试来确定训练是否可以改善手部功能。这些实验的结果有可能通过将探索新颖的协调模式作为训练方案的重要组成部分来改变康复方法。 公众健康相关性：中风后手部运动功能缺陷极为常见。目前的提案旨在通过促进新型手指协调模式的实践来​​改善慢性中风患者的手部功能。