Biorepository Core
生物样本库核心
基本信息
- 批准号:8392594
- 负责人:
- 金额:$ 31.54万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-05-01 至 2017-04-30
- 项目状态:已结题
- 来源:
- 关键词:Authorization documentationBiologicalCharacteristicsClinicalClinical DataClinical ResearchCollectionDNADataData SourcesDatabasesFutureHemophilia AHemostatic functionInformaticsInternetLaboratoriesLinkMaster of ScienceMentorsNCI Scholars ProgramNautilusOnline SystemsPatientsPlasmaReportingResearchResearch InfrastructureResearch PersonnelResearch Project GrantsResourcesRoleSamplingSourceSpecimenSystemTrainingTranslational ResearchUniversitiesVariantbiobankelectronic dataimplementation researchimprovedprograms
项目摘要
The Clinical-Translational Informatics and Biorepository Core (CTIBC) will serve as a central repository of clinical data and biological specimens, including plasma and DNA collected from patients with hemophilia A.
The CTIBC will serve as a resource to coordinate collection and storage of clinical data as well as plasma and DNA to support project 3 aim 3 and project 4 aim 1 and 2. Additionally, the CTIBC will serve as a major resource for the training core as a source of clinical data linked to biological specimens that can be used by trainees and young investigators for new clinical-translational research projects in hemostasis. Having high
quality prospectively collected data linked to biological samples will provide a wealth of opportunity for clinical translational research performed by trainees participating in either the KL-2 Mentored Clinical Research Scholars Program or Master of Science in Clinical Research program.
临床-翻译信息学和生物库核心(CTIBC)将作为临床数据和生物样本的中央储存库,包括从血友病A患者收集的血浆和DNA。
CTIBC将作为协调收集和存储临床数据以及血浆和DNA的资源,以支持项目3 Aim 3和项目4 Aim 1和2。此外,CTIBC将作为培训核心的主要资源,作为链接到生物标本的临床数据来源,供受训者和年轻研究人员用于新的止血临床转化研究项目。有兴奋的
与生物样本相关的高质量预期收集数据将为参加KL-2指导临床研究学者计划或临床研究理学硕士计划的受训人员进行临床翻译研究提供大量机会。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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John S. Lollar其他文献
Cryo-EM Structure of Coagulation Factor VIII Bound to a Patient-Derived Anti-A2 Domain Antibody Inhibitor
- DOI:
10.1182/blood-2023-182304 - 发表时间:
2023-11-02 - 期刊:
- 影响因子:
- 作者:
Kenneth C Childers;Jordan Vaughan;John S. Lollar;Christopher B Doering;Carmen Helena Coxon;P. Clint Spiegel - 通讯作者:
P. Clint Spiegel
John S. Lollar的其他文献
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{{ truncateString('John S. Lollar', 18)}}的其他基金
Unraveling the immune response to factor VIII
揭示对因子 VIII 的免疫反应
- 批准号:
10406900 - 财政年份:2018
- 资助金额:
$ 31.54万 - 项目类别:
The Structural Basis for the Immune Recognition of Factor VIII
因子 VIII 免疫识别的结构基础
- 批准号:
10406902 - 财政年份:2018
- 资助金额:
$ 31.54万 - 项目类别:
Unraveling the immune response to factor VIII
揭示对因子 VIII 的免疫反应
- 批准号:
9522256 - 财政年份:2018
- 资助金额:
$ 31.54万 - 项目类别:
Novel Assays Predicting Phenotypic Heterogeneity in Severe Hemophilia
预测严重血友病表型异质性的新方法
- 批准号:
8464235 - 财政年份:2013
- 资助金额:
$ 31.54万 - 项目类别:
Molecular Heterogeneity in FVIII Inhibitor Patients
FVIII 抑制剂患者的分子异质性
- 批准号:
8464234 - 财政年份:2013
- 资助金额:
$ 31.54万 - 项目类别:
Eradication of FVIII Inhibitors using Gene-Based Therapy
使用基因疗法根除 FVIII 抑制剂
- 批准号:
8391966 - 财政年份:2012
- 资助金额:
$ 31.54万 - 项目类别:
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