Molecular and Cellular Biology & Biochemistry and Structural Biology Graduate Tra

描述（由申请人提供）：分子，细胞和结构生物学（MCSB）培训计划的目标是在分子和细胞水平上提供涉及基础生物学和生物医学过程的各种主题的杰出博士前培训。该项目强调的生物化学、分子生物学、细胞生物学和结构生物学方面的培训将有助于培养我国下一代基础科学家。该培训计划提供了一个多学科的学习课程，可以获得博士学位，并为学生提供了四个专业选择之一的机会：生物化学和分子生物学；细胞与发育生物学；免疫学与病理学；结构生物学。在第一年，所有学生都参加核心课程，包括研究生生物化学，分子遗传学和/或研究生细胞生物学。根据他们的学术专长，未来的课程包括结构生物学和光谱学，细胞和发育生物学，或免疫学和一般病理学。学生们最初还会在期刊俱乐部接受批判性评价原创研究文章的培训。此外，他们还获得了在本科生物实验室担任助教的教学经验。在随后的几年里，他们通过对整个研究生项目进行30分钟的研究研讨会来获得口头报告方面的额外经验。三至四次实验室训练经验，或轮岗，有助于学生选择导师为他/她的论文研究

DESCRIPTION (provided by applicant): The goal of the Molecular, Cellular, and Structural Biology (MCSB) Training Program is to provide outstanding pre-doctoral training on a wide variety of topics involving basic biological and biomedical processes at the molecular and cellular level. The training in biochemistry, molecular biology, cell biology, and structural bioloy emphasized in this program will help to generate the next generation of basic scientists in this country. The training program offers a multidisciplinary course of study leading to the Ph.D. degree and provides students with the opportunity to select one of four specializations: Biochemistry and Molecular Biology; Cellular and Developmental Biology; Immunology and Pathology; and Structural Biology. During the first year all students enroll in core courses including Graduate Biochemistry, Molecular Genetics, and/or Graduate Cell Biology. Depending on their academic specialization future courses include Structural Biology and Spectroscopy, Cell and Developmental Biology, or Immunology and General Pathology. Students also initially receive training to critically evaluate original research articles in a Journal Club. In addition, hey gain teaching experience as Teaching Assistants in undergraduate biology laboratories. In subsequent years they gain additional experience in oral presentation by giving 30-minute seminars on their research to the entire graduate program. Three to four laboratory training experiences, or rotations, serve to help the student to select a mentor for her/his thesis research at completion of her/his first academic year. The MCSB program is quite diverse, crossing departmental and institutional boundaries to offer thesis research training in 72 different mentored laboratories at three institutions: Stony Brook University, Brookhaven National Laboratory, or Cold Spring Harbor Laboratory. There are currently 101 students in the program with approximately 20 admissions per year. Four of the top first year students will be selected by the Executive Committee to be supported as NIH predoctoral trainees for their second year. Assuming the student continues to progress well (as determined by course work, qualifying exam results, and recommendation of the mentor) support can be renewed for their third year. Thus, a total of eight students will be supported each year (four second-year students, and four third-year students). Second year students are required to pass a written qualifying exam. Subsequently, the students present yearly reports on their research progress in a seminar forum to other graduate students, postdoctoral fellows, and faculty. In the third year of the program students prepare a proposal on their intended research project and defend the proposal before a faculty committee. Following successful defense of the proposal, students advance to candidacy and the faculty thesis committee monitors the students' progress until successful completion of the project and defense of a written doctoral thesis.