Molecular and Cellular Biology & Biochemistry and Structural Biology Graduate Tra
分子和细胞生物学
基本信息
- 批准号:8492098
- 负责人:
- 金额:$ 19.76万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1997
- 资助国家:美国
- 起止时间:1997-07-01 至 2017-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant): The goal of the Molecular, Cellular, and Structural Biology (MCSB) Training Program is to provide outstanding pre-doctoral training on a wide variety of topics involving basic biological and biomedical processes at the molecular and cellular level. The training in biochemistry, molecular biology, cell biology, and structural bioloy emphasized in this program will help to generate the next generation of basic scientists in this country. The training program offers a multidisciplinary course of study leading to the Ph.D. degree and provides students with the opportunity to select one of four specializations: Biochemistry and Molecular Biology; Cellular and Developmental Biology; Immunology and Pathology; and Structural Biology. During the first year all students enroll in core courses including Graduate Biochemistry, Molecular Genetics, and/or Graduate Cell Biology. Depending on their academic specialization future courses include Structural Biology and Spectroscopy, Cell and Developmental Biology, or Immunology and General Pathology. Students also initially receive training to critically evaluate original research articles in a Journal Club. In addition, hey gain teaching experience as Teaching Assistants in undergraduate biology laboratories. In subsequent years they gain additional experience in oral presentation by giving 30-minute seminars on their research to the entire graduate program. Three to four laboratory training experiences, or rotations, serve to help the student to select a mentor for her/his thesis research
at completion of her/his first academic year. The MCSB program is quite diverse, crossing departmental and institutional boundaries to offer thesis research training in 72 different mentored laboratories at three institutions: Stony Brook University, Brookhaven National Laboratory, or Cold Spring Harbor Laboratory. There are currently 101 students in the program with approximately 20 admissions per year. Four of the top first year students will be selected by the Executive Committee to be supported as NIH predoctoral trainees for their second year. Assuming the student continues to progress well (as determined by course work, qualifying exam results, and recommendation of the mentor) support can be renewed for their third year. Thus, a total of eight students will be supported each year (four second-year students, and four third-year students). Second year students are required to pass a written qualifying exam. Subsequently, the students present yearly reports on their research progress in a seminar forum to other graduate students, postdoctoral fellows, and faculty. In the third year of the program students prepare a proposal on their intended research project and defend the proposal before a faculty committee. Following successful defense of the proposal, students advance to candidacy and the faculty thesis committee monitors the students' progress until successful completion of the project and defense of a written doctoral thesis.
描述(由申请人提供):分子,细胞和结构生物学(MCSB)培训计划的目标是在分子和细胞水平上提供涉及基本生物学和生物医学过程的各种主题的优秀博士前培训。该计划强调的生物化学,分子生物学,细胞生物学和结构生物学的培训将有助于培养该国下一代基础科学家。该培训计划提供了一个多学科的研究课程,导致博士学位。学位,并为学生提供机会,选择四个专业之一:生物化学和分子生物学;细胞和发育生物学;免疫学和病理学;和结构生物学。在第一年,所有学生都参加核心课程,包括研究生生物化学,分子遗传学和/或研究生细胞生物学。根据他们的学术专业,未来的课程包括结构生物学和光谱学,细胞和发育生物学,或免疫学和一般病理学。学生最初还接受培训,以批判性地评估期刊俱乐部的原创研究文章。此外,他们还获得了在本科生物实验室担任助教的教学经验。在接下来的几年里,他们通过向整个研究生项目提供30分钟的研究研讨会,获得了口头演讲的额外经验。三到四个实验室培训经验,或轮换,帮助学生选择导师为她/他的论文研究
在完成她/他的第一个学年。 MCSB计划是相当多样化的,跨越部门和机构的界限,在三个机构的72个不同的指导实验室提供论文研究培训:斯托尼布鲁克大学,布鲁克海文国家实验室,或冷泉港实验室。目前该计划有101名学生,每年约有20名学生入学。四名顶尖的第一年学生将由执行委员会选出,作为第二年的NIH博士前实习生。假设学生继续进步良好(由课程工作,资格考试成绩和导师的建议确定)支持可以在第三年更新。因此,每年总共将支助8名学生(4名二年级学生和4名三年级学生)。第二年的学生需要通过书面资格考试。随后,学生在研讨会论坛上向其他研究生,博士后研究员和教师提交年度研究进展报告。在该计划的第三年,学生准备对他们打算的研究项目的建议,并在教师委员会面前辩护的建议。在提案成功答辩后,学生将获得候选资格,教师论文委员会将监控学生的进展,直到成功完成项目和书面博士论文答辩。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Robert S. Haltiwanger其他文献
<em>O</em>-Fucose modification is essential for patterning mesoderm in the mouse embryo
- DOI:
10.1016/j.ydbio.2008.05.422 - 发表时间:
2008-07-15 - 期刊:
- 影响因子:
- 作者:
Jianguang Du;Hideyuki Takeuchi;Christina Leonhard;Malgosia Dlugosz;Robert S. Haltiwanger;Bernadette C. Holdener - 通讯作者:
Bernadette C. Holdener
FUT10 and FUT11 are protein O-fucosyltransferases that modify protein EMI domains
FUT10 和 FUT11 是修饰蛋白质 EMI 结构域的蛋白质 O-岩藻糖基转移酶
- DOI:
10.1038/s41589-024-01815-x - 发表时间:
2025-01-07 - 期刊:
- 影响因子:13.700
- 作者:
Huilin Hao;Youxi Yuan;Atsuko Ito;Benjamin M. Eberand;Harry Tjondro;Michelle Cielesh;Nicholas Norris;Cesar L. Moreno;Joshua W. C. Maxwell;G. Gregory Neely;Richard J. Payne;Melkam A. Kebede;Ramona J. Bieber Urbauer;Freda H. Passam;Mark Larance;Robert S. Haltiwanger - 通讯作者:
Robert S. Haltiwanger
13-P011 Restriction of EMT within the primitive streak and correct patterning of the mesoderm requires Pofut2
- DOI:
10.1016/j.mod.2009.06.484 - 发表时间:
2009-08-01 - 期刊:
- 影响因子:
- 作者:
Jianguang Du;Christina L. Leonhard-Melief;Hideyuki Takeuchi;Kenneth R. Shroyer;Malgosia Dlugosz;Robert S. Haltiwanger;Bernadette C. Holdener - 通讯作者:
Bernadette C. Holdener
Analysis of the Healthy Platelet Proteome Identifies a New Form of Domain-Specific emO-/emFucosylation
健康血小板蛋白质组的分析确定了一种新形式的域特异性表情符/纤维糖基化
- DOI:
10.1016/j.mcpro.2024.100717 - 发表时间:
2024-02-01 - 期刊:
- 影响因子:5.500
- 作者:
Callum B. Houlahan;Yvonne Kong;Bede Johnston;Michelle Cielesh;The Huong Chau;Jemma Fenwick;Paul R. Coleman;Huilin Hao;Robert S. Haltiwanger;Morten Thaysen-Andersen;Freda H. Passam;Mark Larance - 通讯作者:
Mark Larance
Novel antibodies detect nucleocytoplasmic O-fucose in protist pathogens, cellular slime molds, and plants
新型抗体检测原生生物病原体、细胞黏菌和植物中的核质 O-岩藻糖
- DOI:
10.1128/msphere.00945-24 - 发表时间:
2025-02-03 - 期刊:
- 影响因子:3.100
- 作者:
Megna Tiwari;Elisabet Gas-Pascual;Manish Goyal;Marla Popov;Kenjiroo Matsumoto;Marianne Grafe;Ralph Gräf;Robert S. Haltiwanger;Neil Olszewski;Ron Orlando;John C. Samuelson;Christopher M. West - 通讯作者:
Christopher M. West
Robert S. Haltiwanger的其他文献
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{{ truncateString('Robert S. Haltiwanger', 18)}}的其他基金
Glycosylation of Thrombospondin Type 1 Repeats
血小板反应蛋白 1 型重复序列的糖基化
- 批准号:
7266505 - 财政年份:2007
- 资助金额:
$ 19.76万 - 项目类别:
Glycosylation of Thrombospondin Type 1 Repeats
血小板反应蛋白 1 型重复序列的糖基化
- 批准号:
7556767 - 财政年份:2007
- 资助金额:
$ 19.76万 - 项目类别:
Glycosylation of Thrombospondin Type 1 Repeats
血小板反应蛋白 1 型重复序列的糖基化
- 批准号:
8018543 - 财政年份:2007
- 资助金额:
$ 19.76万 - 项目类别:
Glycosylation of Thrombospondin Type 1 Repeats
血小板反应蛋白 1 型重复序列的糖基化
- 批准号:
7759150 - 财政年份:2007
- 资助金额:
$ 19.76万 - 项目类别:
Glycosylation of Thrombospondin Type 1 Repeats
血小板反应蛋白 1 型重复序列的糖基化
- 批准号:
7357473 - 财政年份:2007
- 资助金额:
$ 19.76万 - 项目类别:
Gordon Research Conference on Glycobiology 2005/2007
戈登糖生物学研究会议 2005/2007
- 批准号:
6945432 - 财政年份:2004
- 资助金额:
$ 19.76万 - 项目类别:
Gordon Research Conference on Glycobiology 2005/2007
戈登糖生物学研究会议 2005/2007
- 批准号:
7023729 - 财政年份:2004
- 资助金额:
$ 19.76万 - 项目类别:
Gordon Research Conference on Glycobiology 2005/2007
戈登糖生物学研究会议 2005/2007
- 批准号:
6887517 - 财政年份:2004
- 资助金额:
$ 19.76万 - 项目类别:
O-Glycosylation of Epidermal Growth Factor-like Motifs
表皮生长因子样基序的 O-糖基化
- 批准号:
9906932 - 财政年份:2001
- 资助金额:
$ 19.76万 - 项目类别:
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$ 19.76万 - 项目类别:
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