EMBRYOLOGY COURSE

胚胎学课程

• 批准号: 8536925
• 负责人: Alejandro Sanchez Alvarado
• 金额: $ 12.81万
• 依托单位: MARINE BIOLOGICAL LABORATORY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8536925
• 关键词: American; Amphibia; Biological; Caenorhabditis elegans; Collection; Commit; Communities; Computer Assisted; Development; Developmental Biology; Drosophila genus; Educational process of instructing; Embryo; Embryology; Environment; Faculty; Imaging technology; In Situ Hybridization; Individual; International; Laboratories; Laboratory Research; Lead; Leadership; Learning; Libraries; Marines; Methods; Microinjections; Micromanipulation; Microscopy; Molecular; Mus; Planarians; Play; Positioning Attribute; Postdoctoral Fellow; Research; Role; Sea Urchins; Senior Scientist; Series; Students; Techniques; Testing; Training; Zebrafish; animal facility; ascidian; career; doctoral student; experience; instructor; lecturer; lectures

DESCRIPTION (provided by applicant): For nearly 120 years, the Marine Biological Laboratory (MBL) has offered the Embryology Course, which has played an important role in the training of American developmental biologists. The course trains pre-and post-doctoral students for research careers in developmental biology in a unique physical and intellectual environment, not duplicated elsewhere in the nation. The Embryology Course consists of a series of formal lectures, informal seminars, extended discussions, and intensive laboratory research experience delivered over a six-week period in the summer. Course students are selected who are committed to teaching and research careers in the field of developmental biology, and are chosen from a consistently talented pool of national and international applicants. Traditionally, a number of students from each year's class later move into positions of leadership in the worldwide developmental biology community. The teaching faculty are senior scientists in the field, some of whom serve as instructors and lead research modules in the course, and others give lectures and lead discussions of individual topics. The course consists of three modules, each of which is about 2 weeks long. Each module is staffed by an average of three-four resident instructors, plus a comparable number of outside lecturers. The themes of the modules change from year to year as important developments in the field occur. The course introduces students to a large number of terrestrial and marine embryos including C. elegans, Drosophila, planarians, ascidians, sea urchins, zebrafish, amphibians, chick and mouse. Techniques include current molecular biological methods, embryonic manipulation, microinjection and micromanipulation, microscopy and computer-assisted imaging technologies, and a number of immunochemical and in situ hybridization approaches. Students are challenged to formulate and test hypotheses in a well-equipped research environment and under the guidance of experienced research faculty and assistants. In support of the course, the MBL provides a unique learning environment, laboratory and support facilities, an animal collection facility, and one of the nation's finest research libraries.

近120年来，海洋生物实验室（MBL）一直提供胚胎学课程，该课程在培养美国发育生物学家方面发挥了重要作用。该课程培养博士前和博士后学生在发育生物学的研究事业在一个独特的物理和智力环境，而不是在全国其他地方复制。胚胎学课程包括一系列正式讲座，非正式研讨会，扩展讨论，以及在夏季为期六周的密集实验室研究经验。课程学生被选中谁致力于教学和研究事业在发育生物学领域，并从国内和国际申请人的一贯人才库中选择。传统上，A 每年都有一批学生进入世界发育生物学领域的领导岗位。教学人员是该领域的资深科学家，其中一些人担任讲师并领导课程中的研究模块，其他人则进行讲座并领导个别主题的讨论。该课程由三个模块组成，每个模块约2周。每个单元平均配备3 - 4名驻地教员，外加相当数量的外部讲师。随着该领域的重要发展，模块的主题每年都会发生变化。本课程向学生介绍大量的陆地和海洋胚胎，包括C。线虫、果蝇、真涡虫、海鞘、海胆、斑马鱼、两栖动物、小鸡和小鼠。技术包括目前的分子生物学方法，胚胎操作，显微注射和显微操作，显微镜和计算机辅助成像技术，以及一些免疫化学和原位杂交方法。学生面临的挑战是在设备齐全的研究环境中，并在经验丰富的研究教师和助理的指导下，制定和测试假设。在课程的支持下，MBL提供了一个独特的学习环境，实验室和支持设施，动物收藏设施，以及全国最好的研究图书馆之一。