Biostatistics Core

生物统计学核心

• 批准号: 8589114
• 负责人: MARK KESTER
• 金额: $ 2.3万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8589114
• 关键词: Advisory Committees; Animals; Area; Bioinformatics; Biological Markers; Biological Sciences; Biometry; Biostatistics Core; Clinical; Clinical Sciences; Communication; Communities; Computer Hardware; Computer software; Confidentiality; DNA; Data; Data Analyses; Data Collection; Databases; Dose; Ensure; Experimental Designs; Floor; Health Sciences; Human Resources; Institutes; Institution; Knowledge; Learning; Location; Malignant Neoplasms; Manuscripts; Metabolism; Methodology; Preparation; Proteomics; Public Health; Publications; Research; Research Personnel; Resources; Sample Size; Secure; Security; Services; Sphingolipids; Work; cost effectiveness; data integrity; data management; data sharing; design; experience; improved; meetings; member; programs; research study; statistical service; symposium; tool

The Biostatistics Core serves as the focal point of biostatistics support for all the four Projects. The Core will provide regular advice on experimental design such as selection of end points, sample size and power, and optimal allocation of animal and dose. The Core handles data management of the four Projects in a secure central location and in a format consistent across Projects. The Core will perform expert statistical analyses that optimally answer the research question and represent state of the art practice. The Core will also facilitate data sharing with the general scientific community. The Core is staffed by two experienced biostatisticians who have daily working relationships with the Project investigators. Their offices are on the third floor of the Cancer Institute building, in close proximity to most of the Program Project investigators. The Core biostatisticians have been an integral part of the P01 application through working on experimental design, analyzing preliminary data and developing a detailed and tailored statistical plan for each Project. The Core biostatisticians have made a concerted effort to learn the clinical and biological science in this AML Program Project so as to provide the strongest statistical service. The Core has access to all needed software such as Microsoft Office 2007, SAS 9.3 and R. A dedicated Biostatistics Core provides easy and guaranteed access for the Program Project investigators and also allows biostatisticians to specialize in the Project areas, in terms of the scientific knowledge and in biostatistics expertise A dedicated Core provides timely and high quality biostatistics service as its focus. Cost-effectiveness is enhanced because the cumulative experience of all Core personnel and the combined facilities and resources are available to each of the four Projects. The Biostatistics Core also serves as an interface to the larger resources in biostatistics, data management and computing in the Department of Public Health Sciences. No additional computer hardware and software are needed.

生物统计核心是所有四个项目生物统计支持的焦点。核心将定期提供有关实验设计的建议，例如终点的选择、样本量和功效以及动物和剂量的最佳分配。核心在安全的中央位置以跨项目一致的格式处理四个项目的数据管理。核心将进行专家统计分析，以最佳方式回答研究问题并代表最先进的实践。该核心还将促进与广大科学界的数据共享。 核心人员由两名经验丰富的生物统计学家组成，他们与项目研究人员保持日常工作关系。他们的办公室位于癌症研究所大楼的三楼，靠近大多数项目研究人员。核心生物统计学家通过实验设计、分析初步数据以及为每个项目制定详细且量身定制的统计计划，成为 P01 应用程序不可或缺的一部分。在本次AML项目中，核心生物统计学家齐心协力学习临床和生物科学，以提供最强的统计服务。该核心可以访问所有需要的软件，如 Microsoft Office 2007、SAS 9.3 和 R。专用的生物统计核心为计划项目研究人员提供轻松且有保障的访问，还允许生物统计学家在科学知识和生物统计专业知识方面专门研究项目领域 专门的核心以提供及时、高质量的生物统计服务为重点。由于所有核心人员的累积经验以及综合设施和资源可供四个项目中的每一个项目使用，因此成本效益得以提高。生物统计核心还充当公共卫生科学系生物统计、数据管理和计算方面更大资源的接口。不需要额外的计算机硬件和软件。