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中文摘要
翻译
甲状腺癌的翻译研究人员的发展需要勤奋的承诺, 在初级水平上发现有才华的研究人员,并将这些人安置到一个 支持性环境,不仅提供甲状腺癌的重要专业知识, 做导师另一种产生甲状腺癌研究领域领导者的方法是鼓励 成功的转化科学家将他们的才能从其他领域重新集中到这个领域。职业 发展计划(CDP)的这种甲状腺癌孢子是一个重要组成部分的应用程序 因为它提供了一种机制,鼓励优秀的年轻科学家在这一领域建立职业生涯 并吸引来自其他学科的知名研究人员的专业知识。对于这个以甲状腺癌为重点的 应用程序,资源(患者和研究资源)的组合和指导,目前在 俄亥俄州州立大学(OSU)和MD安德森甘瑟中心(MDACC)提供了无与伦比的 环境,使这些新的和初级研究人员能够成功地作为独立的研究人员, 发展未来的职业生涯,这将有助于阻止这种恶性肿瘤发病率上升的进展 并为那些患有局部和远处转移性疾病的人开发新的治疗方法。 为此,CDP将资助有前途的年轻研究人员,或在某些情况下,资助更资深的研究人员。 教师从临床实践或其他领域重新定位2年,每年50,000美元。将特别注意 招聘来自不同背景的申请人。申请将征求所有 OSU和MDACC的部门和中心。CDP领导层将对他们进行资格筛选, 确保合格的妇女和少数民族有足够的代表性。申请将根据以下因素进行评判: 候选人的潜力,拟议研究的实力和导师的适当性。 申请将由CDP委员会成员进行评分和排名,并最终获得资金 向SPORE指导委员会提出建议。每个职位将获得一年的资助, 第二年取决于令人满意的进展。在拨款过程中,SPORE将提供 国家方案文件资金的44.6%,将由38.1%的资金和17.3%的资金由苏丹南部非洲合作委员会提供, MDACC,分别。该计划的成功与否将取决于该计划所产生的科学质量。 获奖者,他们在获得外部同行评审资金方面的成功,他们在学术上的成功 进步,并保留在学术界和甲状腺癌的转化研究。 相关性(参见说明): 职业发展计划(CDP)是这种甲状腺癌的重要组成部分。 申请和国家孢子计划,因为它将确保学术教师的干部谁是 经过专门培训的转化科学家和临床医生,致力于发现和应用新的方法, 了解病原学和流行病学,预防,诊断,治疗和治愈患者 甲状腺癌
英文摘要
The development of translational researchers in thyroid cancer requires a diligent commitment to the identification of talented researchers at the junior level, and the placement pf these individuals into a supportive environment which provides not only significant expertise in thyroid cancer, but also the provision for mentorship. Another way to produce leaders in the field of thyroid cancer research is to encourage successful translational scientists to re-focus their talents from other areas into this area. The Career Development Program (CDP) of this thyroid cancer SPORE is an essential component of the application because it provides the mechanism to encourage excellent junior scientists to establish careers in this field and to attract the expertise of established researchers from other disciplines. For this thyroid cancer-focused application, the combination of resources (both patient and research resources) and guidance present at The Ohio State University (OSU) and at the MD Anderson Gancer Center (MDACC) provides an unparalleled environment to enable these new and junior investigators to succeed as independent researchers and to develop future careers which will contribute to progress in stemming the rising incidence of this malignancy and develop new therapies for those with local and distant metastatic disease. To this end, the CDP will fund promising young investigators or, in certain circumstances, more senior faculty reorienting from clinical practice or another field for 2 years at $50,000 per year. Special attention will be paid to the recruitment of applicants from diverse backgrounds. Applications will be solicited from all departments and centers at OSU and MDACC. They will be screened for eligibility by CDP Leadership to assure adequate representation from qualified women and minorities. Applications will be judged based on the potential of the candidate, the strength of the proposed research and the appropriateness of the mentor. Applications will be scored and ranked by members of the CDP Committee and final funding recommendations made to the SPORE Steering Committee. Each position will be funded for one year, with a second year dependent upon satisfactory progress. Over the course of the grant, the SPORE will provide 44.6% of the funding for the CPD, which will be matched by 38.1%, and 17.3% provided from OSUCCC and MDACC, respectively. Success of the program will be judged by the quality of the science generated by the awardees, their success in obtaining external peer-reviewed funding, their success in academic advancement, and their retention in academia and translational research in thyroid cancer. RELEVANCE (See instructions): The Career Development Program (CDP) is an important component of this thyroid cancer SPORE application and the national SPORE program because it will assure a cadre of academic faculty who are specially trained translational scientists and clinicians dedicated to discover and apply new approaches to understanding the etiology and epidemiology, prevention, diagnosis, treatment and cure of patients with thyroid cancer.
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Single cell transcriptomics of nerves that lack Remak bundles
  • 批准号:
    10649087
  • 项目类别:
  • 资助金额:
    $7.88万
  • 财政年份:
    2023
  • 负责人:
    Lawrence S Kirschner
  • 依托单位:
Identification of enzymes inhibited by oncometabolites in Succinate Dehydrogenase mutant tumors
  • 批准号:
    10579575
  • 项目类别:
  • 资助金额:
    $7.88万
  • 财政年份:
    2023
  • 负责人:
    Lawrence S Kirschner
  • 依托单位:
PKA and follicular thyroid carcinogenesis: Roles of interacting pathways
  • 批准号:
    8514138
  • 项目类别:
  • 资助金额:
    $31.64万
  • 财政年份:
    2013
  • 负责人:
    Lawrence S Kirschner
  • 依托单位:
PKA and follicular thyroid carcinogenesis: Roles of interacting pathways
  • 批准号:
    8826077
  • 项目类别:
  • 资助金额:
    $31.64万
  • 财政年份:
    2013
  • 负责人:
    Lawrence S Kirschner
  • 依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: