Developmental Research Program

发展研究计划

• 批准号: 8588556
• 负责人: Sissy M Jhiang
• 金额: $ 8.83万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8588556
• 关键词: Advertising; Applications Grants; Automobile Driving; Basic Science; Cancer Center; Cancer Patient; Caring; Development; Diagnosis; Elements; Ensure; Funding; Goals; Institution; Investigation; Lead; Malignant neoplasm of thyroid; Mission; Monitor; Ohio; Outcome; Patients; Peer Review; Pilot Projects; Population Sciences; Prevention; Process; Quality of life; Research; Research Personnel; Resources; Source; TNFRSF5 gene; Technology; Therapeutic; Translating; Translational Research; Universities; University of Texas M D Anderson Cancer Center; expectation; high risk; improved; innovation; new technology; outcome forecast; programs; success

The Developmental Research Program (DRP) is an essential component to ensure the continuous success of The Ohio State University/MD Anderson Thyroid Cancer SPORE application. By soliciting and supporting high risk and high impact developmental projects, the DRP will infuse new ideas, new resources, and new technologies that are the driving elements of translational research. The fully developed projects will also provide the SPORE Director with a renewable source of projects that can replace existing SPORE projects, which have been completed or have not fulfilled specific translational expectations. The mission of this SPORE application is to improve therapeutic outcome and life quality for patients with thyroid cancer. Accordingly, the DRP will seek to fund a broad range of proposals from basic science investigation, population science, and innovative approaches that can be translated into better prevention, diagnosis, prognosis, and experimental therapeutics. Drs. Jhiang and Sherman will serve as Co-Leaders to implement an effective DRP. The aims of DRP are: (1) develop a rigorous process to advertise the available resources of the SPORE and to solicit proposals from investigators of broad range of expertise; (2) define a rigorous peer-review process to select meritorious proposals and to monitor annual progress of funded proposals; and (3) provide assistance to promote the funded proposals into full projects within the SPORE or into nationally funded independent grant applications. With the requested SPORE DRP fund and institutional commitnients from OSUCCC and MDACC, we anticipate in funding two new proposals in the year 1 and year 3, one new proposal in the years 2, 4, and 5. Accordingly, a total of seven DRP proposals will be funded throughout the five-year funding period of the SPORE. The two DRPs selected for year 1 are both technology driven, which will lead to new research direction and/or provide new avenue for our battle against thyroid cancer RELEVANCE (See instrucllons): The Developmental Research Program is a component of this Thyroid Cancer SPORE that will fund pilot projects to assist researchers exploring new ideas that will be eventually translated into a better care for thyroid cancer patients. The program will solicit proposals, review, provide funding and promote further development of the selected projects.

发展研究计划(DRP)是确保持续成功的重要组成部分 俄亥俄州立大学/医学博士安德森甲状腺癌孢子应用。通过征集和支持 高风险、高影响的发展项目，将注入新的理念、新的资源、新的 作为翻译研究的驱动因素的技术。全面开发的项目还将 向孢子主管提供可替代现有孢子项目的可再生项目来源， 它们已经完成或没有达到特定的翻译期望。这件事的使命是 应用孢子是为了改善甲状腺癌患者的治疗结果和生活质量。 因此，DRP将寻求资助从基础科学研究到基础科学研究的广泛建议， 人口科学，以及可转化为更好的预防、诊断、 预后和实验治疗学。Jhiang博士和Sherman博士将作为联合领导者实施 一个有效的DRP。DRP的目标是：(1)制定一个严格的程序来宣传可用的资源 并征求具有广泛专业知识的调查人员的建议；(2)界定严格的 同行审查程序，以选择有价值的提案并监测资助提案的年度进展情况； (3)协助将获资助的建议转化为孢子内的完整项目或 国家资助的独立赠款申请。与所要求的孢子DRP基金和机构 OSUCCC和MDACC的承诺，我们预计将在第一年和第二年资助两项新的建议 第3年，第2年、第4年和第5年的一项新提案。因此，总共将资助7项DRP提案 在整个孢子的五年资助期内。为第一年选择的两个DRP都是 技术驱动，这将导致新的研究方向和/或为我们打击 甲状腺癌 相关性(请参阅说明)： 发展研究计划是甲状腺癌孢子的一个组成部分，将资助试点 帮助研究人员探索新想法的项目，这些想法最终将转化为更好的 甲状腺癌患者。该计划将征求建议书、审查、提供资金并进一步促进 选定项目的开发。