Jefferson Alumni Hall Modernization of Cage Sanitation Facility

简介（由申请人提供）：托马斯杰斐逊大学（TJU）是美国最古老的学术医疗中心之一，1824年建立了杰斐逊医学院。杰斐逊校友堂（JAH）是湿台式实验室研究的最大建筑。TJU致力于动物研究的人道关怀和使用。TJU运营着美国农业部、美国法律法规和美国高等教育协会认证的设施。动物资源公司目前在JAH运营着一个24/7/365的设施，占地面积约19,000平方英尺。2至5楼堆叠了1英尺的住房和动物护理支持空间，6楼有一个更大的设施。六楼还包含卫生和看护人员支持区域。根据目前的人口普查，JAH设施约占整个TJU动物项目的26%，但占据了最大的物理足迹。目前，有136名首席研究员根据iacuc批准的451项协议在校园内进行研究。JAH建于1968年。TJU最近委托进行了一项外部研究，确定该建筑的使用寿命超过40年。这项研究产生了一个多年的战略计划，使实验室和实验室支持空间现代化，以提高效率和项目扩展。TJU获得并完成了ARRA设施改造拨款（1 C06 RR028626-01），对大约18,000平方米的设施进行了现代化改造。一英尺的实验室和实验室支持空间。此外，宾夕法尼亚州联邦重建援助资本计划（RACP）拨款允许另外18,000平方英尺。建设现代化实验室和实验室配套空间。新创建的空间与JAH计划的资本投资相一致，将极大地影响该建筑的项目增长。这项和其他正在进行的翻新将使调查人员对动物项目的需求增加约25%，并将对已经过时的笼子卫生设施造成压力。卫生是任何成功的动物研究项目的关键组成部分。超过预期寿命的设备会导致运行中断和能源利用方面的多重效率低下。失败的基础设施不仅影响动物设施，还可能因意外排放的水而破坏其他生产实验室空间。此应用程序请求替换现有设备以及更新相关的基础设施。该设备的采购和安装将提高人员效率，减少停机时间，显著节省运营成本，减少对环境的负面影响。

DESCRIPTION (provided by applicant): Thomas Jefferson University (TJU) is one of the oldest academic health centers in the United States, with establishment of its Jefferson Medical College in 1824. The Jefferson Alumni Hall (JAH) is the largest of the buildings housing wet bench laboratory research. TJU is dedicated to the humane care and use of animals in research. TJU operates USDA-, OLAW- and AAALAC-accredited facilities. Animal Resources currently operates a 24/7/365 facility in JAH in approximately 19,000 sq. ft. of housing and animal care support space in a stacked configuration on floors 2 through 5 with a larger facility on the 6th floor. The 6th floor also contains the sanitation and caretaker staff support areas. JAH facilities represent about 26% of the entire TJU animal program by current census, but occupy the largest physical footprint. Currently there are 136 principal investigators conducting research under 451 IACUC-approved protocols on campus. JAH was constructed in 1968. TJU recently commissioned an external study which determined the building had a useful life of over 40 more years. This study resulted in a multi-year strategic plan to modernize the lab and lab support space for greater efficiency and program expansion. TJU was awarded and has completed an ARRA facilities renovation grant (1 C06 RR028626-01) that modernized approximately 18,000 sq. ft. of lab and lab support space. In addition, a Commonwealth of Pennsylvania Redevelopment Assistance Capital Program (RACP) grant has allowed for another 18,000 sq. ft. of modern lab and lab support space to be constructed. The newly created space in concert with the planned capital investments for JAH will greatly impact program growth in this building. This and other on-going renovations will increase volume of the animal program needs by investigators by about 25% and will stress an already outmoded cage sanitation facility. Sanitation is a critical component to any successful animal research program. Equipment which has exceeded its expected longevity results in multiple inefficiencies both in operational disruption and energy utilization. Failing infrastructure not only impacts the animal facility, but may disrupt other productive lab spaces by accidental discharges of water. This application is requesting the replacement of existing equipment as well as updating associated infrastructure. The procurement and installation of this equipment will result in increased personnel efficiency, less down time, significant operational savings and decreased negative environmental impact.