Cognitive and Affective Dysfunctions in the Psychoses

描述(由申请者提供)：这个新的博士后临床研究培训计划专注于培养专注于精神病患者认知和情感障碍的研究科学家。该计划将利用一种培训模式，强调将认知科学以及认知、社会和情感神经科学的概念和范式引入以患者为导向的、针对精神分裂症和相关精神病的神经认知、社会认知和情绪核心缺陷的临床研究所需的技能。与临床研究人员和认知科学家/神经科学家的直接指导互动将是该计划的一个关键特征，重点是开发和实施针对精神病患者和有此类障碍风险的个人的临床研究。临床研究人员和认知科学家/神经科学家的共同指导将确保发展对调整范式以用于精神障碍研究的原则和方法的理解。该计划的其他培训主题将侧重于研究精神障碍中核心认知和情感功能障碍与功能结果之间的联系，以及研究精神分裂症和相关精神障碍的前驱、首发和慢性期的这些过程。新的培训计划将侧重于拥有临床心理学、认知科学、认知神经科学或情感神经科学博士学位的个人，以及拥有医学博士学位并计划从事研究职业的精神病学住院医生。培训计划将包括(1)通过与共同导师的互动，开发和实施关于精神病认知和情感功能障碍的翻译性临床研究的广泛动手培训，(2)由临床研究人员和认知科学家/神经学家联合教授的每周精神病研究研讨会，(3)每月一次的研究职业发展研讨会，(4)密集的地区职业发展务虚会，(5)针对个人研究兴趣的课程作业、研讨会和实验室培训，以及(6)负责任的研究行为培训。培训将与一些临床研究机会密切结合，使研究参与者能够接触到患有精神分裂症和相关精神障碍的研究参与者。

DESCRIPTION (provided by applicant): This new postdoctoral clinical research training program focuses on developing research scientists who focus on cognitive and affective dysfunctions in psychotic disorders. The program will utilize a training model that emphasizes the skills needed to bring concepts and paradigms from cognitive science and cognitive, social, and affective neuroscience into patient- oriented, clinical research on core deficits in neurocognition, social cognition, and emotion in schizophrenia and related psychoses. Direct mentoring interactions with both clinical investigators and cognitive scientists/neuroscientists wil be a key feature of this program, with the focus being on development and implementation of clinical research with individuals with psychotic disorders and those at risk for such disorders. Co-mentoring by clinical investigators and cognitive scientists/neuroscientists will ensure the development of an understanding of the principles and methods for adapting paradigms for use in research on psychotic disorders. Additional training themes of this program will be an emphasis on research on the links between core cognitive and affective dysfunctions and functional outcome in psychotic disorders and on research that examines these processes across prodromal, first episode, and chronic phases of schizophrenia and related psychotic disorders. The new training program will focus on individuals with Ph.D. in clinical psychology, cognitive science, cognitive neuroscience, or affective neuroscience, and on individuals with an M.D. followed by a psychiatric residency who plan to pursue a research career. The training program will include (1) extensive hands-on training in the development and implementation of translational clinical research on cognitive and affective dysfunctions in psychotic disorders through interactions with the co-mentors, (2) a weekly Research Seminar on the Psychosis taught jointly by clinical researchers and cognitive scientists/neuroscientists, (3) a monthly Research Career Development Seminar, (4) an intensive regional career development retreat, (5) coursework, workshops, and laboratory training tailored to individual research interests, and (6) training in responsible conduct of research. The training will be closely interfaced with a number of clinical research opportunities that allow access to research participants with schizophrenia and related psychotic disorders.