Functional Circuits as an Endophenotype for ADHD in Children

我是一名二年级博士后研究科学家，在耶鲁大学完成研究生培训后来到俄亥俄州立大学 大学医学院，随后又在圣路易斯的华盛顿大学医学院 我主要专注于使用功能磁共振成像和功能成像来检查典型的大脑组织发育 连接核磁共振。我的目标是在一所大学里建立自己的独立实验室 与精神障碍有关的典型和非典型脑发育。特别是，我经过深思熟虑， 关于脑连通性作为潜在内表型的可能性的一系列研究的想法 患有多动症。为了进行这样的工作，我需要在与行为研究应用相关的问题上获得专业知识 临床评估，认知测量，神经心理测量，人类受试者的问题 临床人口，并获得与临床问题有关的写作和恩典方面的专业知识。这 议程是我职业发展/培训计划的重点。俄勒冈州提供的研究环境 健康与科学大学和这一奖项的导师(乔尔·尼格博士)是杰出的，非常适合 我的职业目标。尼格博士虽然不是神经成像师，但他是一位有10多年经验的著名ADHD研究人员 持续提供NIH R01级别的资金。他有丰富的指导经验，并与其他 世界各地的ADHD研究人员，为我提供了大量的机会与专家见面和互动 临床研究的多个方面。独立之路奖，双重强调培训和 独立，非常适合我未来的职业目标。

I am a 2nd year postdoctoral research scientist who arrived at OHSU after postgraduate training first at Yale University School of Medicine, and subsequently Washington University School of Medicine in St. Louis where I primarily focused on examining typical development of brain organization using fMRI and functional connectivity MRI. My goal is to establish my own independent laboratory in a University setting examining typical and atypical brain development in relation to mental disorders. In particular, I have well thought out ideas for a series of investigations regarding the potential for brain connectivity as a potential endophenotype in ADHD. To conduct such work, I need to gain expertise in issues related to research application of behavioral and clinical assessment, cognitive measures, neuropsychological measures, human subjects issues with clinical populations, and to gain expertise in writing and grantsmanship related to clinical problems. This agenda is the focus of my career development/training plan. The research environment provided by Oregon Health and Science University and the mentor of this award (Dr. Joel Nigg) is outstanding and a perfect fit for my career goals. Dr. Nigg, while not a neuroimager, is a well-known ADHD researcher with more than 10 years of continuous NIH R01 level funding. He has extensive mentoring experience and collaborates with other ADHD researchers around the world, providing ample opportunity for me to meet and interact with experts in many aspects of clinical research. The Pathway to Independence award, with its dual emphasis on training and independence, is an excellent fit for my future career goals.