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中文摘要
翻译
描述(由申请人提供):无机药物化学继续作为一个新兴领域,具有开发治疗、成像和其他医疗应用的新型金属药物的巨大潜力。2012年医药金属GRC将汇集来自学术界、产业界和政府的博士科学家和临床医生,在戈登研究会议的轻松环境中讨论被称为药物无机化学的领域的最新发展。我们将通过向少数个人提供会议津贴和小额旅行奖励,以及通过口头海报演示将他们的最佳想法带到会议上的几名年轻研究人员,来吸引尽可能多的学生、博士后和年轻研究人员参加这次会议。2012年医药金属高顿研究会议(GRC)的组织者有四个具体目标。首先,是说明和教授最近批准的基于金属的药物的成功。其次,我们邀请的演讲者将说明在重要的健康相关疾病方面的新研究机会。第三,鼓励未来几代年轻科学家在职业生涯早期参与跨学科研究。出席的几名年轻调查人员将有机会在我们下午的海报会议上口头介绍他们的工作。将邀请外地较资深的主要调查员参加这些介绍,为他们提供指导和反馈。第四,为药物无机化学研究人员提供成核论坛。我们相信,将来自世界各地的学术界、制药开发、政府实验室和临床医生等领域最杰出的研究人员聚集在一起,将为交流想法和新的合作机会提供肥沃的土壤。 与公共健康相关:在设计有利于有机药物的新疗法时,金属离子在控制许多生化过程中的重要性经常被忽视。然而,在设计治疗许多人类疾病的新药时,铁、钙、镁、铜和锌化学在控制生物过程中的重要性怎么强调都不为过。2012年医药金属GRC将汇集来自学术界、产业界和政府的博士科学家和临床医生,在戈登研究会议的轻松环境中讨论被称为药物无机化学的领域的最新发展。
英文摘要
DESCRIPTION (provided by applicant): Inorganic medicinal chemistry continues as an emerging field with tremendous potential for development of new metal-based drugs for therapy, imaging and other medical applications. The 2012 Metals-in-Medicine GRC will bring together PhD scientists and clinicians from academia, industry and government to discuss the latest developments in the field known as medicinal inorganic chemistry in the relaxed environment of a Gordon Research Conference. We will attract as many students, postdocs and young investigators to this meeting as possible by offering conference stipends and small travel awards to a few individuals and by bringing attention to a few young investigators who bring their best ideas to the meeting through oral poster presentations. The organizers of the 2012 Metals-in-Medicine Gordon Research Conference (GRC) have four specific aims. First, is to illustrate and teach about the successes of recently approved metal-based drugs. Second, our invited speakers will illustrate new research opportunities in important health-related disorders. Third, encourage future generations of young scientists to get involved with interdisciplinary research early in their careers. Several young investigators who attend will be offered an opportunity to present their work orally at our afternoon poster sessions. The more senior leading investigators in the field will be asked to participate in these presentation by offering them guidance and feedback. Fourth, to provide a nucleating forum for researchers in medicinal inorganic chemistry. We believe that bringing together the most prominent researchers in academics, pharmaceutical development, government labs and clinicians from around the world will provide a fertile ground for exchange of ideas and opportunities for new collaborations. PUBLIC HEALTH RELEVANCE: The importance of metal ions in controlling many biochemical processes is often overlooked in the design of new therapeutics in favor of organic-based drugs. Nevertheless, the importance of Fe, Ca, Mg, Cu and Zn chemistry in controlling biological processes cannot be overstated in the design of new drugs for many human diseases. The 2012 Metals-in-Medicine GRC will bring together PhD scientists and clinicians from academia, industry and government to discuss the latest developments in the field known as medicinal inorganic chemistry in the relaxed environment of a Gordon Research Conference.
期刊论文(1)
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DOI: 10.1021/ja307098z
发表时间: 2012-10-24
期刊: Journal of the American Chemical Society
影响因子: 15
作者: [Moore JD, Lord RL, Cisneros GA, Allen MJ]
通讯作者: Allen MJ
Imaging beta cell function in vivo with a Zinc responsive MRI contrast agent
  • 批准号:
    8720756
  • 项目类别:
  • 资助金额:
    $34.58万
  • 财政年份:
    2012
  • 负责人:
    Dean Sherry
  • 依托单位:
Imaging beta cell function in vivo with a Zinc responsive MRI contrast agent
  • 批准号:
    8547066
  • 项目类别:
  • 资助金额:
    $33.37万
  • 财政年份:
    2012
  • 负责人:
    Dean Sherry
  • 依托单位:
Imaging Beta Cell Function in Vivo with Zinc Responsive MRI Contrast Agents
  • 批准号:
    10198907
  • 项目类别:
  • 资助金额:
    $40.5万
  • 财政年份:
    2012
  • 负责人:
    Dean Sherry
  • 依托单位:
Imaging beta cell function in vivo with a Zinc responsive MRI contrast agent
  • 批准号:
    8913952
  • 项目类别:
  • 资助金额:
    $34.58万
  • 财政年份:
    2012
  • 负责人:
    Dean Sherry
  • 依托单位:
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