Geriatric Conditions and Disablement in the Older Adult Population
老年人口的老年病和残疾
基本信息
- 批准号:8519187
- 负责人:
- 金额:$ 12.77万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-09-30 至 2015-05-31
- 项目状态:已结题
- 来源:
- 关键词:AccountingAdultAgeAged, 80 and overAgingAppointmentAwardBasic ScienceBrainChronic DiseaseClinicalClinical assessmentsCodeCognitionCognitiveDataData CollectionData SourcesDementiaDemographic AgingDevelopmentDisabled PersonsDiseaseDoctor of MedicineDoctor of PhilosophyEducationEducational workshopElderlyEpidemiologic StudiesEpidemiologyFamily PracticeFoundationsFundingGeriatricsGerontologyGoalsHealthHealth StatusHealthcare SystemsImpaired cognitionImpairmentIncidenceIndividualInstitutesInternal MedicineInterventionInterviewK-Series Research Career ProgramsKnowledgeLeadLinear ModelsLinkMaster of Public HealthMeasuresMedicareMedicare claimMemoryMentorsMentorshipMethodologyMethodsMichiganMinnesotaModelingNational Center for Research ResourcesNational Institute on AgingNational Research Service AwardsOutcomePathway interactionsPatternPerformancePersonsPilot ProjectsPoliciesPopulationPrevalencePrincipal InvestigatorPublic Health SchoolsRecordsResearchResearch PersonnelRespondentRetirementRisk FactorsRoleSamplingScientistSpecific qualifier valueSubgroupSurveysSurvival AnalysisSyndromeTestingTimeTrainingTraining ActivityUnited States Centers for Medicare and Medicaid ServicesUnited States National Institutes of HealthUniversitiesUrinary Incontinencecareercareer developmentcomparativedesigndisabilitydisease diagnosisfallsfrailtylongitudinal analysislongitudinal courselongitudinal designmedical schoolsmiddle agemortalitymultisensorynutritionpopulation basedpreventprofessorprogramsprospectivepublic health relevanceresearch and developmentskillssocialtrend
项目摘要
DESCRIPTION (provided by applicant): Geriatric conditions, although frequently unrecognized and overlooked, are important contributors to the health status of older adults. However, geriatric conditions as a group, in contrast to diseases, have not been clearly located within current models of disability development and progression. Rather, conditions appear to operate and interact at multiple points in these models. Christine Cigolle, M.D., M.P.H. proposes to investigate the place of geriatric conditions in the disablement pathway in older adults for the Mentored Clinical Scientist Research Career Development Award (K08). Dr. Cigolle is an Assistant Professors in the Departments of Family Medicine and Internal Medicine at the University of Michigan (UM) Medical School, with appointments in the Institute of Gerontology (UM) and the VA Ann Arbor Healthcare System Geriatrics Research, Education and Clinical Center (GRECC). Her previous cross-sectional research has demonstrated the prevalence and the disability association of geriatric conditions among older adults. Funded by a NIH-NCRR KL2 Mentored Clinical Scholars Award (UM), she investigated how geriatric conditions and chronic diseases group together in older adults using latent class analysis. Her research for the KL2 Award lays the foundation for the research aims and methodologies in her K08 proposal. The overall goal of the proposed research for the K08 Award is to investigate the place of geriatric conditions in the disablement pathway in the older adult population. The research will examine five geriatric conditions: dementia, falls, urinary incontinence, poor nutrition, and multisensory impairment. The research will propose a conceptual model in which geriatric conditions share common risk factors, have an accelerated trajectory of accumulation in older adults, and result in common outcomes (e.g., disability). The research will test this model, --first, by examining the incidence and longitudinal course of geriatric conditions (individually and in aggregate), beginning with adults in middle age and extending to the oldest old; and --second, by examining geriatric conditions as a predictor of disability (taking mortality into account as a competing outcome). By investigating how geriatric conditions begin, accumulate, and co-occur in older adults over time, the proposed research aims to add new knowledge about the place of geriatric conditions in the disablement pathway and thus to contribute to ongoing efforts to link the conditions theoretically. The proposed research will utilize unique longitudinal data from the Health and Retirement Study (HRS), a nationally-representative health interview survey, and data from the HRS supplemental Aging, Demographics, and Memory Study (ADAMS). It will also make use of newly available Medicare administrative data linked to the HRS and ADAMS to further specify conditions and diseases (diagnosis codes). Dr. Cigolle's career goal is to become an independent researcher in academic Family Medicine, focusing on older adult health status, especially geriatric conditions and syndromes and disability. Her future research methods will focus on implementation and analysis of large epidemiologic studies of older adults. The research and career development training in the K08 Award proposal are designed to support both (1) the acquisition of advanced methodological skills and expertise in the epidemiology of geriatric conditions and (2) training in the design and implementation of primary data collection for large epidemiologic studies of older adults. Her mentorship team for the K08 Award proposal includes: Primary Mentor Jersey Liang, Ph.D., Professor, Department of Health Management and Policy, School of Public Health; Co-Mentor Caroline S. Blaum, M.D., M.S., Professor, Division of Geriatrics, Department of Internal Medicine; and Co-Mentor Kenneth Langa, M.D., Ph.D., Professor, Division of General Internal Medicine, Department of Internal Medicine. Specific career development training activities include: --training in advanced statistical methodologies, including longitudinal analysis, latent trajectory analysis, hierarchical linear modeling, and survival analysis via tutorials with mentors and classwork through the Institute for Social Research and School of Public Health at the University of Michigan, --training in the use of Medicare administrative data via tutorials with mentors and course attendance at CMS 101: Introduction to the Use of Medicare Data for Research (Basic Workshop in Medicare Administrative Data) through the Research Data Assistance Center (ResDAC) at the University of Minnesota, and --training in primary data collection for large epidemiologic studies of older adults via participation in the NIA- funded ADAMS pilot study (National Trends in Brain Health) (Mentor: Langa), development of an experimental module on geriatric conditions to be submitted for consideration for fielding in the 2014 wave of the HRS (Mentor: Langa), and involvement in the Comparative Aging Research Program (Mentor: Liang).
PUBLIC HEALTH RELEVANCE: This research investigates how older adults acquire geriatric conditions, such as falls and urinary incontinence, and how these conditions cause older adults to become disabled. Understanding the early development of geriatric conditions can lead to interventions to prevent or delay them.
描述(由申请人提供):老年疾病,虽然经常未被认识和忽视,但对老年人的健康状况有重要贡献。然而,与疾病不同的是,老年疾病作为一个群体,并没有明确地归入目前的残疾发展和进展模式。相反,在这些模型中,条件似乎在多个点上运行和相互作用。Christine Cigolle,M.D.,M.P.H.建议为指导临床科学家研究职业发展奖(K08)调查老年疾病在老年人残疾途径中的位置。Cigolle博士是密歇根大学(UM)医学院家庭医学和内科的助理教授,曾在老年学研究所(UM)和VA Ann Arbor Healthcare System老年病研究、教育和临床中心(GRECC)任职。她之前的横断面研究已经证明了老年人中老年病的患病率和残疾相关性。在NIH-NCRR KL2指导的临床学者奖(UM)的资助下,她使用潜在类别分析研究了老年疾病和慢性病如何在老年人中分组。她对KL2奖的研究为她K08提案中的研究目标和方法奠定了基础。K08奖拟议研究的总体目标是调查老年人群中老年疾病在致残途径中的位置。这项研究将检查五种老年疾病:痴呆症、跌倒、尿失禁、营养不良和多感官障碍。这项研究将提出一个概念模型,在该模型中,老年疾病共享共同的风险因素,在老年人中加速积累的轨迹,并导致共同的结果(例如,残疾)。这项研究将检验这一模式--首先,检查老年疾病的发病率和纵向病程(个别和总体),从中年成年人开始,延伸到年龄最大的老年人;以及--第二,检查老年疾病作为残疾的预测因素(将死亡率作为一个相互竞争的结果考虑在内)。通过调查老年性疾病是如何随着时间的推移在老年人中开始、积累和共同发生的,拟议的研究旨在增加关于老年性疾病在致残途径中的位置的新知识,从而为正在进行的将这些疾病从理论上联系起来的努力做出贡献。拟议的研究将利用来自健康和退休研究(HRS)的独特纵向数据,这是一项具有全国代表性的健康访谈调查,以及来自HRS补充年龄、人口统计和记忆研究(ADAMS)的数据。它还将利用新获得的与HRS和ADAMS相关的医疗保险管理数据,进一步明确病情和疾病(诊断代码)。Cigolle博士的职业目标是成为学术家庭医学的独立研究员,专注于老年人的健康状况,特别是老年人的状况、症状和残疾。她未来的研究方法将侧重于对老年人进行大规模流行病学研究的实施和分析。K08奖提案中的研究和职业发展培训旨在支持(1)获取老年疾病流行病学方面的先进方法技能和专业知识,以及(2)为老年人的大型流行病学研究设计和实施初级数据收集方面的培训。她的K08奖提名导师团队包括:公共卫生学院健康管理与政策系教授、初级导师梁泽西博士、内科老年病学部教授Caroline S.Blaum、医学博士Caroline S.Blaum和内科普通内科教授Kenneth Langa。具体的职业发展培训活动包括:--通过密歇根大学社会研究所和公共卫生学院的导师辅导和课堂作业,培训高级统计方法,包括纵向分析、潜在轨迹分析、分层线性建模和生存分析;--通过导师辅导和参加CMS 101的课程,培训联邦医疗保险管理数据的使用:通过明尼苏达大学研究数据援助中心(ResDAC)的研究数据援助中心(ResDAC)介绍联邦医疗保险数据用于研究(联邦医疗保险管理数据基本讲习班),以及--通过参与NIA资助的ADAMS试点研究(国家脑健康趋势)(Mentor:LANGA),开发将提交2014年HRS浪潮供考虑的老年条件实验模块(Mentor:LANGA),以及参与比较老龄化研究计划(Mentor:LIGA),为老年人的大型流行病学研究提供初步数据收集方面的培训。
与公共卫生相关:这项研究调查了老年人是如何患上老年疾病的,如跌倒和尿失禁,以及这些疾病是如何导致老年人残疾的。了解老年疾病的早期发展可以导致采取干预措施来预防或延迟这些疾病。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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CHRISTINE T CIGOLLE其他文献
CHRISTINE T CIGOLLE的其他文献
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{{ truncateString('CHRISTINE T CIGOLLE', 18)}}的其他基金
Inconsistencies in Chronic Disease Reports Over Time
慢性病报告随时间的不一致
- 批准号:
8798087 - 财政年份:2014
- 资助金额:
$ 12.77万 - 项目类别:
Geriatric Conditions and Disablement in the Older Adult Population
老年人口的老年病和残疾
- 批准号:
8044584 - 财政年份:2010
- 资助金额:
$ 12.77万 - 项目类别:
Geriatric Conditions and Disablement in the Older Adult Population
老年人口的老年病和残疾
- 批准号:
8716623 - 财政年份:2010
- 资助金额:
$ 12.77万 - 项目类别:
Geriatric Conditions and Disablement in the Older Adult Population
老年人口的老年病和残疾
- 批准号:
8149840 - 财政年份:2010
- 资助金额:
$ 12.77万 - 项目类别:
Geriatric Conditions and Disablement in the Older Adult Population
老年人口的老年病和残疾
- 批准号:
8313939 - 财政年份:2010
- 资助金额:
$ 12.77万 - 项目类别:
Relationship of Frailty to Multimorbidity and Disability
虚弱与多种疾病和残疾的关系
- 批准号:
7056384 - 财政年份:2006
- 资助金额:
$ 12.77万 - 项目类别:
Relationship of Frailty to Multimorbidity and Disability
虚弱与多种疾病和残疾的关系
- 批准号:
7193531 - 财政年份:2006
- 资助金额:
$ 12.77万 - 项目类别:
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