Blood-borne infection screening in an Afghan antenatal population

阿富汗产前人群的血源性感染筛查

• 批准号: 7977128
• 负责人: Catherine Suzanne Todd
• 金额: $ 10.37万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-29 至 2010-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7977128
• 关键词: Admission activity; Afghanistan; Award; Blood; California; Caring; Counseling; Data; Data Analyses; Development; Diagnostic Procedure; Discipline of obstetrics; Environment; Epidemic; Epidemiologic Studies; Family Planning; Fellowship; Goals; Gynecologist; HIV; Health; Health Personnel; Hepatitis B; Hepatitis B Virus; Hospitals; Infection; Infection prevention; Infectious Disease Epidemiology; Infectious Diseases Research; International; Intervention; Intervention Studies; Knowledge; Learning; Maternal Health; Medical; Medicine; Mentors; Methodology; Methods; Needs Assessment; Patients; Perception; Population; Prevalence; Prevention; Provider; Psychometrics; Reproductive Health; Research; Research Design; Resources; Risk; Risk Reduction; Screening procedure; Sexually Transmitted Diseases; Surveys; Syphilis; Testing; Time; Training; Universities; Virus Diseases; Work; career; design; improved; professor; programs; reproductive; skills; theories

DESCRIPTION (provided by applicant): This award will provide Dr. Catherine Todd with protected time and expertise to develop international research in risk reduction of blood-borne viral infections (BBV) and sexually-transmitted infections (STI) during reproductive care in limited-resource settings. Dr. Todd is an obstetrician/gynecologist who completed a family planning fellowship and worked as an international consultant, with the majority of time spent in Afghanistan. She is currently Assistant Professor in the Division of International Health & Cross-Cultural Medicine at the University of California, San Diego. Her career and training goals are to: 1. Gain knowledge in advanced epidemiologic study design, particularly observational and intervention research; 2. Acquire survey development and psychometric methodology skills; 3. Improve understanding of the intersection of reproductive health and infectious disease research in international settings; 4. Learn BBV/STI diagnostic methods suited to resource-poor environments; 5. Acquire advanced quantitative data analysis proficiency; 6. Conduct a study investigating prevalence and correlates of and barriers to screening for human immunodeficiency virus (HIV), syphilis, and hepatitis B (HBV) in an Afghan antenatal population; and 7. Learn international health programming theory to design and pilot an intervention implementing antenatal screening. The training plan includes coursework and mentoring by experts in infectious disease epidemiology, international maternal health, and psychometric scale methods. A key component is a needs assessment study and a pilot intervention to implement antenatal testing. The aims of the proposed research are to: 1) Determine prevalence and correlates of HIV, syphilis, and HBV in an antenatal population in Kabul, Afghanistan, 2) Assess patient knowledge and perceptions on screening value for HIV, syphilis, and HBV in obstetric care, 3) Assess knowledge and practice of medical personnel and their influence on HIV, syphilis, and HBV prevention counseling, screening, and iatrogenic infection prevention practice, and 4) Determine feasibility and acceptance of antenatal screening at hospital admission for obstetric patients and providers in Kabul, Afghanistan. Though little is known about BBV prevalence in Afghanistan, multiple factors increase the risk of an epidemic, particularly the antenatal population; implementing testing may circumvent this. Pilot data generated from this study will be used to test the intervention in a larger Afghan population.

描述（由申请人提供）：该奖项将为 Catherine Todd 博士提供受保护的时间和专业知识，以开展国际研究，以降低资源有限环境中生殖保健期间血源性病毒感染 (BBV) 和性传播感染 (STI) 的风险。托德博士是一名妇产科医生，完成了计划生育奖学金并担任国际顾问，大部分时间都在阿富汗度过。她目前是加州大学圣地亚哥分校国际健康与跨文化医学系的助理教授。她的职业和培训目标是： 1. 获得高级流行病学研究设计的知识，特别是观察和干预研究； 2. 获得调查开发和心理测量方法技能； 3. 提高对国际背景下生殖健康和传染病研究交叉点的了解； 4.学习适合资源匮乏环境的BBV/STI诊断方法； 5. 获得高级定量数据分析能力； 6. 开展一项研究，调查阿富汗产前人群中人类免疫缺陷病毒（HIV）、梅毒和乙型肝炎（HBV）的流行率、相关性和筛查障碍； 7. 学习国际健康规划理论，以设计和试点实施产前筛查的干预措施。培训计划包括传染病流行病学、国际孕产妇保健和心理测量量表方法方面专家的课程作业和指导。一个关键组成部分是需求评估研究和实施产前检测的试点干预。拟议研究的目的是：1) 确定阿富汗喀布尔产前人群中 HIV、梅毒和 HBV 的患病率和相关性，2) 评估患者对产科护理中 HIV、梅毒和 HBV 筛查价值的知识和看法，3) 评估医务人员的知识和实践及其对 HIV、梅毒和 HBV 预防咨询、筛查的影响， 和医源性感染预防实践，以及 4) 确定阿富汗喀布尔产科患者和提供者入院时产前筛查的可行性和接受度。尽管人们对阿富汗 BBV 的流行情况知之甚少，但多种因素增加了流行病的风险，尤其是产前人群；实施测试可能会规避这一点。这项研究产生的试点数据将用于测试对更多阿富汗人口的干预措施。

项目成果

Attitudes and practices of obstetric care providers in Kabul, Afghanistan regarding antenatal testing for sexually transmitted infection.

阿富汗喀布尔产科护理人员对性传播感染产前检测的态度和做法。

• DOI: 10.1111/j.1552-6909.2008.00283.x
• 发表时间: 2008
• 期刊: Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
• 作者: Todd,CatherineS;Ahmadzai,Malalay;Smith,JeffreyM;Siddiqui,Hadia;Ghazanfar,SyedAlefShah;Strathdee,SteffanieA
• 通讯作者: Strathdee,SteffanieA

Cross-sectional analysis of factors associated with prior contraceptive use among hospitalized obstetric patients in Kabul, Afghanistan.

对阿富汗喀布尔住院产科患者既往避孕措施相关因素的横断面分析。

• DOI: 10.1016/j.contraception.2008.05.005
• 发表时间: 2008
• 期刊: Contraception
• 影响因子: 2.9
• 作者: Todd,CatherineS;Isley,MichelleM;Ahmadzai,Malalay;Azfar,Pashtoon;Atiqzai,Faridullah;Smith,JeffreyM;Ghazanfar,SayedAlefShah;Strathdee,SteffanieA;Miller,Suellen
• 通讯作者: Miller,Suellen

Implications of hepatitis C viremia vs. antibody alone on transmission among male injecting drug users in three Afghan cities.

丙型肝炎病毒血症与单独抗体对阿富汗三个城市男性注射吸毒者传播的影响。

• DOI: 10.1016/j.ijid.2010.11.006
• 发表时间: 2011
• 期刊: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
• 作者: Nasir,Abdul;Todd,CatherineS;Stanekzai,MohammadR;Bautista,ChristianT;Botros,BoulosA;Scott,PaulT;Kim,JeromeH;Strathdee,SteffanieA;Tjaden,Jeffrey
• 通讯作者: Tjaden,Jeffrey

Prevalence and correlates of syphilis and condom use among male injection drug users in four Afghan cities.

• DOI: 10.1097/olq.0b013e3181e2c76a
• 发表时间: 2010-11
• 期刊: Sexually transmitted diseases
• 影响因子: 3.1
• 作者: Todd CS;Nasir A;Raza Stanekzai M;Abed AM;Strathdee SA;Bautista CT;Scott PT;Botros BA;Tjaden J
• 通讯作者: Tjaden J

Prevalence of human immunodeficiency virus infection, risk behavior, and HIV knowledge among tuberculosis patients in Afghanistan.

阿富汗结核病患者的人类免疫缺陷病毒感染率、危险行为和艾滋病毒知识。

• DOI: 10.1097/olq.0b013e318095068a
• 发表时间: 2007
• 期刊: Sexually transmitted diseases
• 影响因子: 3.1
• 作者: Todd,CatherineS;Barbera-Lainez,Yolanda;Doocy,ShannonC;Ahmadzai,Ahmadullah;Delawar,FaisM;Burnham,GilbertM
• 通讯作者: Burnham,GilbertM