ASBMR Symposium: Cutting Edge Discoveries in Muscle Biology, Disease and Therapeu

摘要： 美国每年花费数十亿美元用于肌肉骨骼 疾病儿童时期的肌肉和骨骼疾病可能会摧毁任何正常人的希望。 肌肉和骨骼的生命和衰老疾病导致肌肉和骨骼损失， 肌肉减少症和骨质疏松症传统上，骨骼和肌肉 被单独研究。尽管一些研究人员研究了这两种组织， 规范是只专注于其中一个。由于存在着紧密的联系 肌肉和骨骼在整个发展，生长和衰老，我们建议把 肌肉和骨骼研究人员一起研究这两者之间的相互作用， 组织中2012年7月举行的主题会议，重点关注骨骼和肌肉 互动活动取得了成功，吸引了270名与会者。保值增值 我们计划在会议开始前一天， ASBMR 2013年度会议，以最新的前沿研究正在作出 肌肉场。这次会议的具体目标是： 目前肌肉生物学的前沿研究，重点是肌肉细胞，肌肉 收缩之外的功能，以及治疗和临床应用的发展 2）开始识别肌肉骨骼中的区域 这项研究将通过肌肉之间的合作得到显著的推进， 和骨骼研究者这将通过要求发言者的投入来实现， 主席和与会者在会后的调查。每届会议将 由会议联合主席总结并张贴在ASBMR网站上， 提供一个论坛，促进新的互动和未来的合作， 肌肉和骨骼研究者研讨会将提供机会， 在两次海报会议和午餐期间，研究者之间进行了互动。这些 具体目标将通过邀请国际知名的肌肉研究人员来实现 来展示他们关于肌肉细胞的最新数据， 收缩性，以及肌肉疾病的治疗和临床治疗。与会者 在本次会议上，将鼓励参加ASBMR 2013年年会， 年会与会者将被鼓励参加这个为期一天的研讨会， 目的是在肌肉-骨骼相互作用和串扰方面产生新的想法， 建立新的合作。将继续讨论产生的主题 从专题会议，如是否建立一个联合研究领域， 整合肌肉和骨骼生理学是可行的。的最终目标 研讨会是为了更好地了解肌肉和骨骼的相互作用， 为了确定和实施新的治疗策略，将提高和 保持肌肉骨骼健康。

Abstract: Billions of dollars are spent annually in the United States on musculoskeletal diseases. Diseases of muscle and bone in childhood can ravage any hopes of a normal life and aging diseases of muscle and bone results in muscle and bone loss, the conditions known as sarcopenia and osteoporosis. Traditionally, bone and muscle have been studied separately. Whereas some researchers have studied both tissues, the norm is to focus exclusively on one or the other. As a tight association exists between muscle and bone throughout development, growth and aging, we are proposing to bring together both muscle and bone researchers to study interactions between these two tissues. A topical meeting that was held in July 2012 to focus on bone and muscle interactions was a success, drawing 270 attendees. To maintain and increase the momentum generated by this topical meeting we plan to dedicate a day before the ASBMR 2013 Annual Meeting to the most recent cutting edge research being made in the muscle field. The specific aims to be accomplished by this meeting are 1) To present cutting edge research in muscle biology focusing on the cells of muscle, muscle function beyond contraction, and development of therapeutics and clinical applications for muscle wasting and disease, 2) To begin to identify areas in musculoskeletal research that would be significantly advanced through collaboration between muscle and bone researchers. This will be accomplished by requesting input from the speakers, chairs and attendees in a survey following the meeting. Each session will be summarized by the session co-chairs and posted on the ASBMR website and 3) To provide a forum for facilitating new interactions and future collaborations between muscle and bone researchers. The symposium will provide opportunities for interactions between investigators at the two poster sessions and during lunch. These specific aims will be accomplished by inviting internationally known muscle researchers to present their latest data on the cells of muscle, the functions of muscle beyond contractility, and the therapeutics and clinical treatments for muscle disease. Attendees at this meeting will be encouraged to attend the ASBMR 2013 Annual Meeting and Annual Meeting attendees will be encouraged to attend this one-day symposium with the aim to generate new ideas in muscle-bone interactions and crosstalk leading to the establishment of new collaborations. Discussion will continue on themes generated from the topical meeting such as whether establishing a combined research field that integrates both muscle and bone physiology is feasible. The ultimate goal of the symposium is to generate a better understanding of muscle and bone interactions in order to identify and implement new therapeutic strategies that will enhance and maintain musculoskeletal health.