Decision Making For Active Surveillance in Prostate Cancer Patients and Spouses

前列腺癌患者和配偶主动监测的决策

基本信息

  • 批准号:
    8534064
  • 负责人:
  • 金额:
    $ 18.06万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2012
  • 资助国家:
    美国
  • 起止时间:
    2012-09-01 至 2015-08-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Prostate cancer is the most common site of cancer in men in the United States with over 240,000 men diagnosed with prostate cancer in 2011. Over the past years, widespread prostate specific antigen (PSA) screening has resulted in the earlier detection of these cancers. Screening has also led to controversy as men with very early stage disease are being treated when it is not clear to what extent treatment may be of benefit to them. Many clinicians agree that early stage disease is being over treated and it is estimated that 27-56% of men who undergo treatment for early stage prostate cancer can be managed effectively with active surveillance (AS). Given the potential for significant side-effects (e.g., erectile dysfunction, urinary incontinence, and bowl irritation) associated with treatment, AS is an important and viable alternative for patients with low-grade disease. Physicians have noticed that psychological factors such as anxiety or certain disease and treatment related beliefs may be influencing men and their partners to select active treatment (AT) over AS. In addition, intimate partners often exert an important influence of treatment choice as they are the primary social support for cancer patients. These anecdotal observations are supported by theory (i.e., self- regulation theory) and reports in the literature. However, a systematic examination of the influence of these cognitive-affective and social factors on the decision to decide on and adhere to an AS regimen is missing. The present application aims to investigate the decision making process for AS using a theory-guided self- regulation approach focusing on cognitive, affective and social/partner factors. This will be the first comprehensive examination of the contribution of affective and cognitive processes to decision making for AS. It will also be the first in this literature to include the perspective of patients' partners on decision making through the use of qualitative and quantitative data collection methods. Thus, the specific aims are: 1) to explore the cognitive and affective treatment decision-making processes among prostate cancer patients who are eligible for active surveillance and their partners/close allies. Aim 2: To explor how patients arrived at their decision and to investigate the influence partners/close allies play in this process.
描述(由申请人提供):前列腺癌是美国男性最常见的癌症部位,2011 年有超过 240,000 名男性被诊断出患有前列腺癌。在过去的几年中,广泛的前列腺特异性抗原 (PSA) 筛查使得这些癌症得以早期发现。筛查也引起了争议,因为在尚不清楚治疗对他们有多大益处的情况下,患有早期疾病的男性正在接受治疗。许多临床医生都认为早期前列腺癌治疗过度,据估计,接受早期前列腺癌治疗的男性中有 27-56% 可以通过主动监测 (AS) 得到有效管理。鉴于与治疗相关的潜在显着副作用(例如勃起功能障碍、尿失禁和碗刺激),AS 对于低度疾病患者来说是一种重要且可行的替代方案。医生注意到,焦虑或某些疾病和治疗相关信念等心理因素可能会影响男性及其伴侣选择积极治疗(AT)而不是 AS。此外,亲密伴侣往往对治疗选择产生重要影响,因为他们是癌症患者的主要社会支持。这些轶事观察得到理论(即自我调节理论)和文献报告的支持。然而,缺乏对这些认知情感和社会因素对决定和坚持 AS 治疗方案的影响的系统研究。本申请旨在使用理论指导的自我调节方法来研究 AS 的决策过程,重点关注认知、情感和社会/伴侣因素。这将是对贡献的第一次全面审查 AS 决策的情感和认知过程。这也将是该文献中第一个通过使用定性和定量数据收集方法纳入患者伴侣对决策的观点的文献。因此,具体目标是:1)探索有资格接受主动监测的前列腺癌患者及其伴侣/亲密盟友的认知和情感治疗决策过程。目标 2:探索患者如何做出决定,并调查合作伙伴/亲密盟友在此过程中发挥的影响力。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Social ecological influences on treatment decision-making in men diagnosed with low risk, localised prostate cancer.
  • DOI:
    10.1111/ecc.13697
  • 发表时间:
    2022-11
  • 期刊:
  • 影响因子:
    2.1
  • 作者:
    McIntosh, Megan;Opozda, Melissa J.;Short, Camille E.;Galvao, Daniel A.;Tutino, Rebecca;Diefenbach, Michael;Ehdaie, Behfar;Nelson, Christian
  • 通讯作者:
    Nelson, Christian
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Michael A Diefenbach其他文献

USING GROWTH CURVE MODELING TO EXAMINE QUALITY OF LIFE AMONG PROSTATE CANCER SURVIVORS: RESULTS FROM A 36 MONTHS LONGITUDINAL STUDY
  • DOI:
    10.1016/s0022-5347(08)61156-8
  • 发表时间:
    2008-04-01
  • 期刊:
  • 影响因子:
  • 作者:
    Michael A Diefenbach;William Dudley
  • 通讯作者:
    William Dudley

Michael A Diefenbach的其他文献

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{{ truncateString('Michael A Diefenbach', 18)}}的其他基金

Reducing Burden in Care Partners of Community-Dwelling Persons with Dementia and Oropharyngeal Dysphagia
减轻社区居民痴呆症和口咽吞咽困难患者护理伙伴的负担
  • 批准号:
    10570435
  • 财政年份:
    2023
  • 资助金额:
    $ 18.06万
  • 项目类别:
Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
  • 批准号:
    10216197
  • 财政年份:
    2018
  • 资助金额:
    $ 18.06万
  • 项目类别:
Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
  • 批准号:
    10436957
  • 财政年份:
    2018
  • 资助金额:
    $ 18.06万
  • 项目类别:
Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
  • 批准号:
    10672260
  • 财政年份:
    2018
  • 资助金额:
    $ 18.06万
  • 项目类别:
Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CA
促进肌肉侵袭性膀胱 CA 患者决策的新方法
  • 批准号:
    8876159
  • 财政年份:
    2015
  • 资助金额:
    $ 18.06万
  • 项目类别:
Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CA
促进肌肉侵袭性膀胱 CA 患者决策的新方法
  • 批准号:
    9057990
  • 财政年份:
    2015
  • 资助金额:
    $ 18.06万
  • 项目类别:
Decision Making For Active Surveillance in Prostate Cancer Patients and Spouses
前列腺癌患者和配偶主动监测的决策
  • 批准号:
    8386407
  • 财政年份:
    2012
  • 资助金额:
    $ 18.06万
  • 项目类别:
Brief Intervention to Improve QOL & Couple Functioning after Prostate Surgery
改善生活质量的简短干预
  • 批准号:
    8301574
  • 财政年份:
    2011
  • 资助金额:
    $ 18.06万
  • 项目类别:
Brief Intervention to Improve QOL & Couple Functioning after Prostate Surgery
改善生活质量的简短干预
  • 批准号:
    8190005
  • 财政年份:
    2011
  • 资助金额:
    $ 18.06万
  • 项目类别:
Trajectories of QOL in Prostate Cancer Survivors using Growth Curve Modeling
使用生长曲线模型研究前列腺癌幸存者的生活质量轨迹
  • 批准号:
    7476125
  • 财政年份:
    2008
  • 资助金额:
    $ 18.06万
  • 项目类别:

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