Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
基本信息
- 批准号:10672260
- 负责人:
- 金额:$ 49.72万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-07-01 至 2024-12-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAftercareAgeAreaAttentionBladderBody ImageCancer InterventionCancer PatientCaregiversCaringCategoriesClimactericClinicalCombined Modality TherapyComplexCost AnalysisDataData AnalysesDevelopmentDiagnosisDiseaseDistressEducationEmergency CareEmergency department visitEvaluationExcisionFaceFeelingFemaleFrightFutureGenderGoalsHealth ProfessionalHealth PromotionHome visitationHospitalsIleal conduit procedureInfectionInformation ResourcesInstructionInterventionKnowledgeLearningLiteratureMaintenanceMalignant neoplasm of urinary bladderMediatingMediatorMedicalModelingOnline SystemsOperative Surgical ProceduresParticipantPatient CarePatientsPersonsPhasePhysiciansPilot ProjectsPreparationProstatePublishingQuality of lifeRandomizedRandomized, Controlled TrialsRecoveryRecovery SupportRecurrenceRegimenResearchResearch MethodologySamplingSavingsSelf CareSelf EfficacySpousesStomasSystemTechnologyTestingTimeTreatment EfficacyVisitVisiting NurseWorkcaregivingclinical applicationclinical carecomparison groupcopingcostcost effectiveexperiencegroup interventionhealth traininghuman old age (65+)implementation costimprovedinnovationintervention costintervention effectlymph nodesmultimodalitymuscle invasive bladder cancernovelprimary outcomeprogramspsychologicpsychosocialreadmission ratessecondary outcomeskillssocialstandard of caresurvivorshiptherapy designusabilityweb-based intervention
项目摘要
ABSTRACT
Treatment for muscle invasive bladder cancer (MIBC) involves the removal of the bladder and construction of a
new voiding system and is physically and psychologically profoundly challenging for patients and caregivers.
Based on our published literature and extensive pilot data, patients and caregivers have extensive unmet
informational, social, psychological, instrumental, and medical needs from the time of diagnosis, through
treatment and recovery which are not adequately addressed by health care professionals. We propose to
address these unmet needs through the refinement and evaluation of a comprehensive, 2-part (in-person and
web-based) intervention, geared towards the patient and caregiver. Specifically, during Aim 1, the formative
phase, we propose to further refine our newly developed intervention components with the help of an
established patient/caregiver advisory board. The intervention, Recovery Support for Bladder Cancer (RSBC),
consists of a pre-treatment, in-person preparatory instructional session with a trained health care professional
(Module 1) to equip patients and caregivers with the skills to adjust to the upcoming treatment and recovery
period. This is followed by a post-treatment, interactive web-based program (Module 2) to provide further
support for both patients and caregivers to enhance quality of life (QOL) and reduce infections and nurse/ER
visits. The RSBC intervention will be evaluated in a 12-month randomized controlled trial (Aim 2) among
patients and caregiver dyads (N=330 initial; 230 final sample) against a time and attention comparison
condition that incorporates standard of care discharge instructions and modules focusing on wellness. Primary
outcomes for both patients and caregivers will be improved QOL, which is hypothesized to be significantly
higher among participants randomized into RSBC. Secondary outcomes will be fewer infections and nurse-
ER visits for patients randomized into RSBC. Aim 3 proposes moderator (i.e., age, gender, surgical diversion
type) and mediator (i.e., patient activation, distress) analyses of intervention efficacy. We hypothesize that
RSBC will be significantly more successful among (a) older, (b) female participants, and (c) patients with a
conduit diversion type. Elevated levels of patient activation (i.e., higher self-care knowledge, self-efficacy, lower
distress) will mediate the intervention effects. Exploratory Aim 4 will examine the costs and potential savings
associated with developing and implementing the RSBC intervention. We hypothesize that initial development
and implementation costs of RSBC will be offset by reduced nurse/ER visits. The scientific premise is strong
and supported by an established theoretical framework, extensive pilot data and a rigorous application of
clinical research methods. The proposed study is highly innovative, as it comprehensively addresses unmet
needs of both patients and caregivers from pre- and (immediate) post-treatment to recovery. This is achieved
through an innovative combination of in-person preparation and skill-building and web-based technology. If
successful, RSBC has the potential to significantly change clinical care for patients and caregivers with MIBC.
摘要
项目成果
期刊论文数量(5)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Management of Distress in Patients with Cancer-Are We Doing the Right Thing?
- DOI:10.1093/abm/kaaa091
- 发表时间:2020-12-01
- 期刊:
- 影响因子:0
- 作者:Dekker J;Graves KD;Badger TA;Diefenbach MA
- 通讯作者:Diefenbach MA
Patterns of alcohol use among early head and neck cancer survivors: A cross-sectional survey study using the alcohol use disorders identification test (AUDIT).
- DOI:10.1016/j.oraloncology.2021.105328
- 发表时间:2021-08
- 期刊:
- 影响因子:4.8
- 作者:Teckie, Sewit;Wotman, Michael;Marziliano, Allison;Orner, David;Yi, Jungen;Mulvany, Colm;Ghaly, Maged;Parashar, Bhupesh;Diefenbach, Michael A.
- 通讯作者:Diefenbach, Michael A.
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Michael A Diefenbach其他文献
USING GROWTH CURVE MODELING TO EXAMINE QUALITY OF LIFE AMONG PROSTATE CANCER SURVIVORS: RESULTS FROM A 36 MONTHS LONGITUDINAL STUDY
- DOI:
10.1016/s0022-5347(08)61156-8 - 发表时间:
2008-04-01 - 期刊:
- 影响因子:
- 作者:
Michael A Diefenbach;William Dudley - 通讯作者:
William Dudley
Michael A Diefenbach的其他文献
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{{ truncateString('Michael A Diefenbach', 18)}}的其他基金
Reducing Burden in Care Partners of Community-Dwelling Persons with Dementia and Oropharyngeal Dysphagia
减轻社区居民痴呆症和口咽吞咽困难患者护理伙伴的负担
- 批准号:
10570435 - 财政年份:2023
- 资助金额:
$ 49.72万 - 项目类别:
Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
- 批准号:
10216197 - 财政年份:2018
- 资助金额:
$ 49.72万 - 项目类别:
Recovery Support for Bladder CA Patients and Caregivers: A Multimodal Approach
膀胱 CA 患者和护理人员的康复支持:多模式方法
- 批准号:
10436957 - 财政年份:2018
- 资助金额:
$ 49.72万 - 项目类别:
Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CA
促进肌肉侵袭性膀胱 CA 患者决策的新方法
- 批准号:
8876159 - 财政年份:2015
- 资助金额:
$ 49.72万 - 项目类别:
Novel Approach to Facilitate Decisions in Patients w/ Muscle Invasive Bladder CA
促进肌肉侵袭性膀胱 CA 患者决策的新方法
- 批准号:
9057990 - 财政年份:2015
- 资助金额:
$ 49.72万 - 项目类别:
Decision Making For Active Surveillance in Prostate Cancer Patients and Spouses
前列腺癌患者和配偶主动监测的决策
- 批准号:
8534064 - 财政年份:2012
- 资助金额:
$ 49.72万 - 项目类别:
Decision Making For Active Surveillance in Prostate Cancer Patients and Spouses
前列腺癌患者和配偶主动监测的决策
- 批准号:
8386407 - 财政年份:2012
- 资助金额:
$ 49.72万 - 项目类别:
Brief Intervention to Improve QOL & Couple Functioning after Prostate Surgery
改善生活质量的简短干预
- 批准号:
8301574 - 财政年份:2011
- 资助金额:
$ 49.72万 - 项目类别:
Brief Intervention to Improve QOL & Couple Functioning after Prostate Surgery
改善生活质量的简短干预
- 批准号:
8190005 - 财政年份:2011
- 资助金额:
$ 49.72万 - 项目类别:
Trajectories of QOL in Prostate Cancer Survivors using Growth Curve Modeling
使用生长曲线模型研究前列腺癌幸存者的生活质量轨迹
- 批准号:
7476125 - 财政年份:2008
- 资助金额:
$ 49.72万 - 项目类别:
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