Comparative Effectiveness of Interventions for Depression in the Community

社区抑郁症干预措施的比较有效性

• 批准号: 8487835
• 负责人: Mary Beth Gibbons
• 金额: $ 15.51万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-02 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8487835
• 关键词: Comparative; Effectiveness; Interventions; Depression; Community

PROJECT SUMMARY The goal of this independent research scientist award application is to protect the time necessary to further develop my skills as a newly independent researcher specializing in comparative effectiveness of interventions for depression in the community mental health system. This award would allow me to become a sophisticated comparative effectiveness researcher utilizing state-of-the-art methodologies and statistical approaches to study the effectiveness of interventions in alleviating mental health disorders of high public health priority. My program of research and planned career development activities are based on the definition of comparative effectiveness research elaborated by the Institute for Medicine's Committee on Comparative Effectiveness Research Prioritization. It is my goal to work with expert consultants and participate in training activities to take my comparative effectiveness research program to the next level. To complement my current program of research evaluating the effectiveness of interventions for depression in the community mental health system that inform clinical decision making at the population level, my goal is to develop expertise in methods and statistical approaches that would allow my research to address the important question of how to efficiently disseminate effective interventions to meet the needs of individual consumers of services for depression. This award would afford me the time needed to participate in classroom instruction in the newest statistical approaches, attend training seminars and institutes, work with expert consultants, and attend conferences to enhance my development as a comparative effectiveness researcher. This award would also allow me the time, expert consultation, and education needed to conduct two important studies to inform the efficient dissemination of interventions for depression in the community: a study of the patient baseline moderators of treatment effectiveness and a study of healthcare utilization and costs associated with the utilization of mental health interventions for MDD in the community mental health system. The specific aims of this investigation include 1) to assess whether patient baseline skills deficits moderate the effectiveness of dynamic therapy and cognitive therapy for patients with major depressive disorder treated in the community mental health setting, 2) to assess whether patient baseline deficits moderate the effectiveness of dynamic therapy and cognitive therapy on secondary measures of outcome, 3) to explore additional baseline patient variables that may moderate the effectiveness of these psychotherapeutic approaches for patients with major depressive disorder treated in the community mental health setting, and 4) to evaluate healthcare utilization and associated costs for patients treated with psychotherapy for depression in the community mental health system compared to patients who receive alternative treatments.

项目概要 这项独立研究科学家奖申请的目的是保护进一步研究所需的时间 培养我作为一名新独立研究员的技能，专门研究干预措施的比较有效性 社区心理健康系统中的抑郁症。这个奖项将使我成为一个成熟的人 比较有效性研究人员利用最先进的方法和统计方法 研究干预措施在减轻公共卫生高度优先的精神健康障碍方面的有效性。我的 研究计划和计划的职业发展活动以比较的定义为基础 医学研究所比较有效性委员会详细阐述的有效性研究 研究优先顺序。与专家顾问合作并参加培训活动是我的目标 我的比较有效性研究计划更上一层楼。为了补充我目前的计划 评估社区心理卫生系统中抑郁症干预措施有效性的研究 为人口层面的临床决策提供信息，我的目标是发展方法和方法方面的专业知识 统计方法将使我的研究能够解决如何有效地解决这一重要问题 传播有效的干预措施，以满足抑郁症服务个体消费者的需求。这 该奖项将为我提供参与最新统计数据的课堂教学所需的时间 方法、参加培训研讨会和机构、与专家顾问合作并参加会议 促进我作为比较有效性研究者的发展。这个奖项也让我 进行两项重要研究所需的时间、专家咨询和教育，以便为有效的决策提供信息 在社区中传播抑郁症干预措施：一项针对抑郁症患者基线调节因素的研究 治疗效果以及与心理治疗相关的医疗保健利用和成本研究 社区心理健康系统中 MDD 的健康干预措施。本次调查的具体目的 包括 1) 评估患者基线技能缺陷是否会影响动态治疗的有效性，以及 对在社区心理健康机构接受治疗的重度抑郁症患者进行认知治疗，2) 评估患者基线缺陷是否会调节动态治疗和认知治疗的有效性 治疗结果的次要测量，3) 探索可能的额外基线患者变量 调节这些心理治疗方法对重度抑郁症患者的有效性 在社区心理健康环境中接受治疗，4) 评估医疗保健利用率和相关成本 与在社区心理卫生系统中接受抑郁症心理治疗的患者相比 接受替代治疗的患者。