Translational Proteomics: Biology, Technology and Clinical Advances

描述（由申请人提供）：我们请求部分资金支持，用于2013年3月10日至13日在马里兰州巴尔的摩举行的美国人类蛋白质组组织（US-HUPO）题为“翻译蛋白质组学：生物学、技术和临床进展”的2013年年会的运作。自2005年第一届美国HUPO会议以来，该场地一直是并将继续成为蛋白质组学高度跨学科科学领域的重要会议，特别是针对生物学和临床问题。US-HUPO是一个独特的科学家会议，因为它真正反映了多学科的相互作用， 使蛋白质组学研究人员能够接近和解决复杂的生物医学问题。US-HUPO会议致力于促进各种技术平台的临床应用和转化，包括质谱法，蛋白质微阵列，生物传感器，临床检测，生物标志物发现和诊断，预后和治疗目的的验证。US-HUPO会议出席人数众多，一直吸引着该领域的一流演讲者。2013年年会将再次汇集蛋白质组学前沿的杰出和多样化的科学家。研讨会的特邀演讲者将明确讨论与心血管疾病、癌症和传染病等广泛疾病相关的应用。由于近年来取得的技术进步对于使科学家能够更有效地解决生物学问题至关重要，蛋白质组学的技术未来也将是会议的一个标志。选择的主题将教育参与者最新，最有效的技术和方法，说明这些技术成功地转化为临床，并强调该领域未来的新方向和重大挑战。将就关键主题举行互动小组讨论，以鼓励演讲者和与会者之间进行强有力的对话，讨论蛋白质组学未来的关键目标，概述预期的障碍，并集思广益解决方案。今年US-HUPO将继续在生物学，技术和临床进展方面非常成功的平行职业发展会议，为早期研究人员提供对蛋白质组学增长领域的重要见解和专业发展策略。海报会议还将提供一个更非正式的科学思想和进步的交流。将有充足的时间用于社交场所，让与会者相互见面，建立新的联系和合作。目前，30%的受邀演讲者是妇女或少数群体成员。一旦该计划完成从提交的摘要中选择，我们预计将有至少35%的女性和少数民族发言人，以及至少35%的早期研究人员（助理教授，博士后和/研究生）。预计出席人数为350-450人，包括100-150名学生/博士后。注册不受限制，所有感兴趣的人都可以参加。将特别努力招募少数民族和工业参与者;鉴于巴尔的摩在东海岸的中心地理位置，后者应该很容易实现。参加者将在每天下午展示新发现的海报。重要的是，这次会议为年轻的研究人员提供了一个论坛，让他们看到基础科学探究与科学方法应用于设计人类疾病有效干预措施之间的联系。为了强调这一目标，将挑选28个以上与会议主题相辅相成的海报介绍作简短的口头介绍，发言时间从以往会议的10分钟增加到15分钟。最后，值得注意的是，在会议之前，US-HUPO提供了几个关于蛋白质组学当代主题的半天短期课程。

DESCRIPTION (provided by applicant): We request partial funding support for operation of the 2013 Annual Meeting of the United States Human Proteome Organization (US-HUPO) entitled "Translational Proteomics: Biology, Technology and Clinical Advances", to be held March 10-13, 2013 in Baltimore, Maryland. Since the first US HUPO meeting in 2005, this venue has been and continues to be a vital conference for the highly interdisciplinary scientific field of proteomics, particularly as directed towards biological and clinical questions. US-HUPO is a unique meeting of scientists because it truly reflects the multidisciplinary interactions that have allowed proteomic researchers to approach and solve sophisticated biomedical problems. The US-HUPO meeting endeavors to promote the clinical application and translation of diverse technological platforms including mass spectrometry, protein microarrays, biosensors, clinical assays to biomarker discovery and validation for diagnostic, prognostic and treatment purposes. The US-HUPO conference is heavily attended and has always attracted first-rate speakers in this field. The 2013 Annual Meeting will again bring together an outstanding and diverse group of scientists at the forefront of proteomics. Invited speakers in the symposium will explicitly discuss applications relevant to a wide range of diseases including cardiovascular disease, cancer, and infectious diseases. As technological advances made in the recent years are of critical importance in enabling scientists to more effectively address biological problems, the technological future of proteomics will also be a hallmark of the meeting. The topics chosen will educate participants on the latest, most effective technologies and methods, illustrate successful translation of these technologies into the clinic, and highlight new directions and grand challenges for the future of this field. Interactive panel discussions will be held on key topics in order to encourage a robust dialogue between speakers and meeting participants to discuss critical goals for the future in proteomics, outline anticipated obstacles, and brainstorm solutions. This year US-HUPO will continue highly successful parallel Career Development sessions in Biology, technology and clinical advances, to provide early stage investigators with crucial insights into growth areas in proteomics and strategies for professional development. The poster sessions will also offer a more informal exchange of scientific ideas and advances. Ample time will be devoted to social venues for attendees to meet each other and establish new contacts and collaborations. Currently, 30% of the invited speakers are either women or members of minority groups. Once the program is completed with selections from submitted abstracts, we expect to have at least 35% women and minority speakers, and at least 35% early stage investigators (assistant professors, post-docs and/ graduate students). Attendance is expected to be 350-450 participants, including 100-150 students/post-docs. Registration is not restricted, and all interested persons may attend. A special effort will be made to recruit minorit and industrial participants; the latter should be readily achievable given the central geographic location of Baltimore in the East coast. Participants will present posters on new findings each afternoon. Importantly, the conference provides a forum for young investigators to see the connection between fundamental scientific inquiry and the application of scientific methods to the design of efficacious interventions for human disease. To emphasize this goal, over 28 poster presentations that complement the themes of the meeting will be selected for short oral presentations with an increased time to 15 minutes from 10 minutes during the past meetings. Finally, it is important to note that, preceding the meeting, US-HUPO offers several Half-Day short courses on contemporary topics in proteomics.