VALIDATION OF THE IPQ-R ADAPTED FOR COLORECTAL CANCER RISK

IPQ-R 适用于结直肠癌风险的验证

• 批准号: 8399720
• 负责人: ANJALI D DESHPANDE
• 金额: $ 18.65万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-12-12 至 2014-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8399720
• 关键词: Address; Adherence; Adult; Affect; Age; Behavior; Behavior Therapy; Belief; Cancer Etiology; Cancer Patient; Cessation of life; Chronic; Clinic; Cognitive; Colorectal Cancer; Critiques; Cross-Sectional Studies; Data; Diabetes Mellitus; Diagnosis; Disease; Disease Outcome; Disease model; Education; Effectiveness; Emotional; Equation; Face; Family health status; Fright; Future; Gender; Guidelines; Health; Health Communication; Health behavior; Health behavior change; Healthcare; Individual; Informal Social Control; Intervention; Intervention Studies; Lead; Low income; Malignant Neoplasms; Measurement; Measures; Methods; Minority; Modeling; Modification; Morbidity - disease rate; Patients; Persons; Prevention; Preventive; Process; Property; Psychometrics; Questionnaires; Race; Recording of previous events; Research Personnel; Resources; Review Literature; Risk; Screening for cancer; Structure; Subgroup; Theoretical model; TimeLine; United States; Validation; Woman; Work; base; cancer prevention; cancer risk; colorectal cancer screening; coping; disorder prevention; evidence base; illness perceptions; improved; instrument; interest; men; mortality; novel; response; screening; success; therapy design

DESCRIPTION (provided by applicant): Colorectal cancer (CRC) is the third most common cause of cancer and cancer death in the USA. Despite the availability of evidence-based screening and prevention methods for CRC, rates of screening adherence have been suboptimal. Most behavioral interventions designed to increase CRC screening (CRCS) have had limited success. Interventions based on a theoretical model such as Leventhal's Self-Regulation Model (or Common-Sense Model of Illness Representations) that incorporates both the cognitive and emotional influences on behavior may be more effective for promoting cancer screening behaviors. Understanding illness representations (i.e., cause, control, timeline, consequences, identity, coherence, emotional) is particularly valuable because it identifies targets for interventions to restructure disease-related beliefs, which then would lead to more favorable health behaviors and disease outcomes. It also may increase receptivity to specific messages, thereby improving the effectiveness of health communication-based interventions. Few studies have examined illness representations for disease threats or health risks among healthy individuals, as we propose in the current study. Additionally, among the few studies that have examined illness risk representations, different measures are used and not all domains are assessed in every study, which highlights the need for standard, validated measures of illness risk representations among healthy persons. The Revised Illness Perceptions Questionnaire (IPQ-R) has been adapted for numerous diseases and conditions and used with diagnosed and healthy individuals, but not CRC or CRC risk. Critiques of the IPQ-R suggest that simple adaptations will produce imprecise measures and fail to capture disease-specific beliefs; therefore, we extended the IPQ-R to include additional items and subscales based on our formative work and reviews of the literature. The objective of the study is to produce a novel validated instrument to measure illness representations of CRC risk. We will accomplish this with a large cross-sectional survey to address the following specific aims: Aim 1) Determine the factor structure (number of domains) of the new IPQ-R adapted for CRC risk; Aim 2) Determine the measurement equivalence of the new IPQ-R adapted for CRC risk across specific subgroups defined by gender, race, diabetes status, and CRCS status; and Aim 3) Examine the construct validity and additional correlates of the new IPQ-R adapted for CRC risk. The new instrument will be an important resource for researchers for identifying new avenues for improving intervention research to increase CRCS and other cancer prevention behaviors which would then reduce CRC morbidity and mortality.

描述（由申请人提供）：结直肠癌（CRC）是美国第三大癌症和癌症死亡原因。尽管有基于证据的结直肠癌筛查和预防方法，但筛查依从率一直不理想。大多数旨在增加结直肠癌筛查 (CRCS) 的行为干预措施取得的成功有限。基于 Leventhal 自我调节模型（或疾病表征常识模型）等理论模型的干预措施结合了认知和情绪对行为的影响，可能更有效地促进癌症筛查行为。了解疾病表征（即原因、控制、时间线、后果、身份、连贯性、情感）特别有价值，因为它确定了重建疾病相关信念的干预目标，从而导致更有利的健康行为和疾病结果。它还可以提高对特定信息的接受度，从而提高基于健康传播的干预措施的有效性。正如我们在当前研究中提出的那样，很少有研究检查健康个体中疾病威胁或健康风险的疾病表征。此外，在检查疾病风险表征的少数研究中，使用了不同的测量方法，并且并非每项研究都评估所有领域，这突出表明需要对健康人中的疾病风险表征进行标准的、经过验证的测量。修订后的疾病认知调查问卷 (IPQ-R) 已针对多种疾病和病症进行了调整，并适用于已诊断和健康的个体，但不适用于 CRC 或 CRC 风险。对 IPQ-R 的批评表明，简单的调整会产生不精确的测量结果，并且无法捕捉特定疾病的信念；因此，我们根据我们的形成性工作和文献综述扩展了 IPQ-R，以包含其他项目和分量表。该研究的目的是开发一种新的经过验证的工具来衡量 CRC 风险的疾病表征。我们将通过大型横断面调查来实现这一目标，以实现以下具体目标： 目标 1) 确定适合 CRC 风险的新 IPQ-R 的因子结构（域数量）；目标 2) 确定适用于按性别、种族、糖尿病状况和 CRCS 状况定义的特定亚组的 CRC 风险的新 IPQ-R 的测量等效性；目标 3) 检查适用于 CRC 风险的新 IPQ-R 的结构有效性和其他相关性。该新仪器将成为研究人员的重要资源，用于确定改进干预研究的新途径，以增加CRCS和其他癌症预防行为，从而降低CRC发病率和死亡率。