Portable hand-held non-mydriatic retinal camera

便携式免散瞳眼底照相机

• 批准号: 8453271
• 负责人: Peter N Soliz
• 金额: $ 18.91万
• 依托单位: VISIONQUEST BIOMEDICAL, LLC
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8453271
• 关键词: Adoption; Affect; Age; American; Applications Grants; Area; Caring; Clinic; Clinical; Collaborations; Consult; Consultations; Contracts; Development; Device or Instrument Development; Devices; Diabetes Mellitus; Diabetic Retinopathy; Diet Habits; Disease; Doctor of Philosophy; Environment; Exercise; Eye; Eye diseases; Family; Fundus; Glaucoma; Goals; Hand; Healthcare; Image; Impairment; Individual; Institutes; International; Laboratories; Lead; Legal patent; Marketing; Measures; Medical; Medical Device; Metric; Mydriatics; Names; Non-Insulin-Dependent Diabetes Mellitus; Nurses; Ophthalmologist; Optics; Overweight; Phase; Physician Executives; Physicians; Population; Primary Care Physician; Principal Investigator; Production; Recording of previous events; Resolution; Retina; Retinal; Rural; Safety; Services; Solutions; South Texas; Staging; System; Systems Development; Technology; Telemedicine; Testing; Time; Training; Travel; United States National Institutes of Health; Vision; Work; adaptive optics; age related; base; commercialization; cost; design; diabetic; disease diagnosis; ergonomics; experience; human subject; meetings; operation; portability; prevent; programs; prototype; public health relevance; screening; success

DESCRIPTION (provided by applicant): According to the National Institutes of Health, there are more than 80 million people in the US who suffer from a potentially sight-threatening disease. Doctors see seven to eight million new cases of eye disease annually. More than two million Americans age 50 and older have advanced AMD, the stage that can lead to severe vision impairment and 10 million have early or intermediate AMD. Glaucoma affects more than 2.3 million Americans age 40 and older. Another two million individuals with glaucoma are undiagnosed. Diabetes cases in the US and throughout the world have been on the rise. Poor eating habits and lack of exercise, factors which contribute to type 2 diabetes, have led to an increasingly overweight population. According to the International Diabetes Federation, there are 285 million cases of diabetes in the world as of 2010. For the type 2 diabetics, 50% will develop diabetic retinopathy within 15 years of disease diagnosis. Regular eye disease screening is necessary to prevent the progression of eye diseases to advanced, sight-threatening stages. The objective of this project is to develop and test a low-cost, hand-held, non-mydriatic retinal camera for widespread applications, including teleretinal screening for eye diseases such as diabetic retinopathy, glaucoma, and age-related ocular diseases. The proposed camera fills an important unmet need: low-cost (under $1,500 cost of goods); small footprint (principally a hand-held device); and easy to use (ergonomically designed for operation by a minimally trained medical technician or nurse). Introducing this technology to a clinic environment will allow underserved individuals to receive regular eye screenings without traveling to an eye care professional. To meet this goal, our proposal has two aims. First, we will produce a prototype of the low-cost, hand-held, non-mydriatic camera, which will be based on an early prototype of a mydriatic camera that was developed, and for which early testing has shown significant functionality. The design is based on low-cost, off-the-shelf components that can be assembled easily for a high- volume market. Second, we will test this camera in a screening or clinic environment. Making the camera ergonomically suitable for use by a minimally trained individual will be the goal of this aim. Quantitative analysis will be performed as to field of view, resolution, and safety.

描述(申请人提供)：根据美国国立卫生研究院的数据，美国有超过8000万人患有一种潜在威胁视力的疾病。医生每年看到700到800万新的眼病病例。超过200万50岁及以上的美国人患有晚期AMD，这一阶段可能导致严重的视力障碍，1000万人患有早期或中期AMD。青光眼影响着230多万40岁及以上的美国人。另有200万青光眼患者未确诊。美国和世界各地的糖尿病病例一直在上升。不良的饮食习惯和缺乏锻炼是导致2型糖尿病的因素，导致了越来越多的超重人口。根据国际糖尿病联合会的数据，截至2010年，世界上有2.85亿糖尿病病例。对于2型糖尿病患者，50%的患者将在疾病诊断后15年内发展为糖尿病视网膜病变。定期进行眼病筛查是必要的，以防止眼病发展到严重威胁视力的阶段。该项目的目标是开发和测试一种低成本、手持、非散瞳的视网膜相机，用于广泛应用，包括对糖尿病视网膜病变、青光眼和与年龄相关的眼部疾病进行远程筛查。拟议中的摄像头满足了一个重要的未得到满足的需求：低成本(不到1500美元的商品成本)；占地面积小(主要是手持设备)；以及易于使用(符合人体工程学的设计，由受过最低培训的医务人员或护士操作)。将这项技术引入诊所环境，将允许服务不足的人接受定期眼部筛查，而无需前往眼科护理专业人员那里。为了实现这一目标，我们的建议有两个目标。首先，我们将 生产低成本、手持、非散瞳相机的原型，这将基于开发的散瞳相机的早期原型，早期测试显示其具有重要功能。这种设计基于低成本、现成的组件，可以很容易地组装成大批量市场。其次，我们将在筛查或临床环境中测试这款相机。让相机符合人体工程学，适合受过最低程度训练的个人使用，将是这一目标的目标。将对视场、分辨率和安全性进行定量分析。