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Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome

Lifecourse Exposures & Diet: Epigenetics, Maturation & Metabolic Syndrome
生命全程暴露
批准号:
8512938
负责人:
VASANTHA PADMANABHAN
金额:
$67.72万
依托单位国家:
美国
项目类别:
财政年份:
2013
资助国家:
美国
项目状态:
已结题
起止时间:
2013-07-01 至 2018-05-31
关键词:
AddressAdultAdvisory CommitteesAffectAgeAmino AcidsAnimalsAreaAwardBioinformaticsBiological MarkersBiometryBirthCadmiumCarnitineChildChild DevelopmentChild health careChildhoodChromatin Remodeling FactorChromatin StructureChronic DiseaseClinicalCollaborationsCommunicationCommunitiesCommunity HealthcareCommunity OutreachComplexDNA MethylationDataData AnalysesDatabasesDevelopmentDevelopment PlansDevelopmental BiologyDietDietary intakeDisciplineDiseaseDisease susceptibilityElementsEndocrine DisruptorsEnsureEnvironmental ExposureEnvironmental HealthEnvironmental Risk FactorEpidemiologyEpigenetic ProcessExposure toFacultyFetal DevelopmentFosteringFundingGene Expression ProfileGene Expression RegulationGenesGenetic TranscriptionGoalsGovernmentGrowthHealthHealth ProfessionalHomeostasisHormonal ChangeHumanInfantInfluentialsInformaticsInterdisciplinary StudyInterventionKnowledgeLeadLearningLettersLifeLife Cycle StagesLiteratureMetabolicMetabolic syndromeMetabolismMethylationMexicoMichiganModelingMothersNational Institute of Environmental Health SciencesNonesterified Fatty AcidsNutritionalObesityOutcomeOutputOutreach ResearchOxidative StressPerinatalPerinatal ExposurePhenotypePlayPoliciesPolicy MakerPopulation StudyPositioning AttributePredispositionPregnancy in AdolescencePrevention ResearchPrincipal InvestigatorProceduresProcessProtocols documentationPublic HealthQuality ControlRelative (related person)ReportingResearchResearch DesignResearch InfrastructureResearch PersonnelResearch Project GrantsResourcesRiskRisk AssessmentRoleSamplingScientistSecureServicesSexual MaturationSpecialistStagingStressThinkingTissuesToxic Environmental SubstancesTrainingTraining ActivityTranslational ResearchTranslationsTyrosineUnited States Environmental Protection AgencyUnited States National Institutes of HealthUniversitiesVisionWeightbasebehavior influencebisphenol Abody systemcareercareer developmentcohortcostdata managementdata miningdesigndevelopmental plasticitydiscountdisorder preventionearly life exposureepigenomeepigenomicsfetalfollow-upin uteroinsightinterdisciplinary approachmeetingsmembermetabolomicsnext generationnovelnutritionorganizational structureoxidationperipubertal periodphthalatespostnatalprogramsranpirnasereproductive hormoneresponseskillssuccesstooltranscriptomics

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中文摘要
翻译
描述(由申请人提供) 行政核心(AC)的总体目标是监督、协调和整合中心的活动。具体目标是:1)协调和整合项目和核心的科学目标,跟踪和评估进展和产出,并确保成功完成所有中心目标;2)管理资源,确保每个项目和核心的需求和优先事项得到满足;3)作为协调中心,召开项目、核心和分包调查员会议,组织外部咨询委员会,确保研究结果的及时翻译,准备中心范围的报告,并与NIEHS和EPA项目官员沟通;4)评估职业发展计划的进展和成功,特别是教师发展调查员的职业发展;5)确保研究所有阶段的质量控制,即研究设计、建立标准操作程序和研究方案、安全样本和数据传输和管理、数据分析,以及向学术、政府、医疗保健和社区利益相关者准确解释和翻译研究结果。咨询中心将在核心共同领导、顾问和儿科健康专家的指导下,与每个项目和核心的领导合作。咨询委员会将确保协调中心的活动,管理跨项目和核心的资源,确定基础设施和通信的最有效利用,并在出现需求时解决需求,以提高中心的效率和生产性产出。AC领导人将与外部咨询委员会互动,以确保UM-CEHC所有要素的优点和价值,以实现中心的整体目标。中心经理将优先协调社区外联和翻译核心,以优化对社区利益攸关方的外联和研究翻译。最后,咨询委员会将监督新调查员的职业发展和培训,特别是被指定为学院发展调查员的UM-CEHC联合调查员。职业发展和培训活动将利用广泛的机构资源,并将与中心的研究项目和核心充分结合。
英文摘要
DESCRIPTION (provided by applicant) The overall goal of the Administrative Core (AC) is to provide oversight, coordination and integration of Center activities. The specific aims are to: 1) Coordinate and integrate the scientific aims of the Projects and Cores, track and evaluate progress and outputs, and ensure successful completion of all Center aims; 2) Manage resources to assure the needs and priorities of every Project and Cores are met; 3) Act as coordinating center by convening meetings of Project, Core, and subcontract investigators, organize External Advisory Committee, ensure timely translation of research findings, prepare Center-wide reports, and interface with NIEHS and EPA project officers; 4) Evaluate the progress and success of the career, development plan, with specific focus on the career development of Faculty Development Investigator; 5) Ensure quality control of all stages of research namely study design, establishment of standard operating procedures and study protocols, secure sample and data transfer and management, data analysis, and accurate interpretation and translation of research findings to academic, government, healthcare and community stakeholders. The AC will operate under the direction of the Core co-Leaders, Consultant, and Pediatric Health Specialist in collaboration with Leaders of each Project and Core. The AC will ensure coordination of Center activities, manage resources across Projects and Cores, identify the most efficient use of infrastructure and communication and resolve needs as they arise, in order to increase the efficiency and productive output of the Center. AC Leaders will interact with the External Advisory Board to ensure the merit and value of all UM-CEHC elements to accomplish the overall Center aims. The Center Manager will prioritize coordination with the Community Outreach and Translation Core to optimize outreach and research translation to community stakeholders. Finally, the AC will oversee career development and training of New Investigators, particularly the UM-CEHC Co-investigator designated as the Faculty Development Investigator. Career development and training activities will draw upon extensive institutional resources and will be fully integrated with the Center's Research Projects and Cores.
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Gestational Hyperandrogenism in Cardiovascular Programming
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    10472623
  • 项目类别:
  • 资助金额:
    $3.55万
  • 财政年份:
    2020
  • 负责人:
    VASANTHA PADMANABHAN
  • 依托单位:
Gestational Hyperandrogenism in Cardiovascular Programming
  • 批准号:
    10705060
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2020
  • 负责人:
    VASANTHA PADMANABHAN
  • 依托单位:
Gestational Hyperandrogenism in Cardiovascular Programming
  • 批准号:
    10745470
  • 项目类别:
  • 资助金额:
    $72.54万
  • 财政年份:
    2020
  • 负责人:
    VASANTHA PADMANABHAN
  • 依托单位:
Gestational Hyperandrogenism in Cardiovascular Programming
  • 批准号:
    10256011
  • 项目类别:
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  • 财政年份:
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  • 负责人:
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  • 依托单位:
海外基金