Core C: Research Support Core: Bioinformatics and Molecular Modeling

核心 C：研究支持 核心：生物信息学和分子建模

• 批准号: 8723397
• 负责人: STEFANO MONTI
• 金额: $ 0.78万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8723397
• 关键词: Address; Bioinformatics; Biological Assay; Chemistry; Cods; Collaborations; Communication; Communication Research; Communities; Computer software; Data; Decision Making; Development; Environmental Health; Federal Government; Goals; Government Agencies; Hazardous Waste; Hazardous Waste Sites; Health; Individual; Information Dissemination; Instruction; Knowledge; Life; Massachusetts; Methods; Modeling; Molecular Models; National Institute of Environmental Health Sciences; New England; Outcomes Research; Productivity; Public Health; Public Sector; Reagent; Regulation; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Resources; Rhode Island; Risk Assessment; Signal Recognition Particle; State Government; Superfund; Techniques; Technology; Technology Transfer; Toxic effect; Toxicology; Training; Translational Research; Water; Work; base; environmental chemical; improved; meetings; molecular modeling; programs; receptor; reproductive; superfund chemical; tool; willingness

PROJECT SUMMARY (See Instructions): The purpose of the Research Translation Core is to make research outcomes available to governmental organizations responsible for protecting the health of local communities, to the scientific community in general, and to other SRPs in particular. This is in addition to organizations engaged with the BU SRP through the Community Engagement Core. The principal goal is to provide knowledge of exposure and health effects useful in risk assessment needed for consequential decision-making. This proposal builds on our previous work and includes new partners who can use the SRP and Project results for assessment, regulation and reduction of contaminants found at hazardous waste sites. Specific Aim 1: Coordinate communication of research within BU SRP, in New England, and the larger NIEHS SRP community to improve application of findings, provide access to data, consolidate resources and increase productivity and collaboration. Specific Aim 2: Develop and. maintain partnerships with governmental environmental and public health agencies and provide them with data and expertise that might improve risk assessment-based decisions, particularly with respect to developmental and reproductive effects of environmental chemicals. Specific Aim 3: Effect technology transfer by identifying potential end-users of technologies, assays and resources developed by BU SRP projects and facilitate their application. Specific Aim 4: Pursue, initiate and implement Center-specific research translation activities (i.e., emanating from the BU SRP), working with the Community Engagement and Training Cores to have a broader impact.

项目总结(见说明)： 研究翻译核心的目的是将研究成果提供给负责保护当地社区健康的政府组织、科学界，特别是其他可持续发展计划。这还不包括通过社区参与核心参与BU SRP的组织。主要目标是提供有关暴露和健康影响的知识，这对后续决策所需的风险评估是有用的。这项建议建立在我们以前工作的基础上，并包括新的合作伙伴，他们可以使用SRP和项目结果来评估、监管和减少危险废物场地发现的污染物。 具体目标1：协调新英格兰BU SRP和更大的NIEHS SRP社区内的研究沟通，以改进研究结果的应用，提供数据访问，整合资源，提高生产率和协作。 具体目标二：发展和发展。与政府环境和公共卫生机构保持伙伴关系，并向它们提供数据和专门知识，以改进基于风险评估的决策，特别是在环境化学品的发展和生殖影响方面。 具体目标3：通过查明技术、化验和资源的潜在最终用户实现技术转让，并促进这些项目的应用。 具体目标4：开展、发起和实施中心特有的研究翻译活动(即，源自波士顿大学SRP)，与社区参与和培训中心合作，以产生更广泛的影响。