Fenway Adolescent Trials Unit

描述(由申请人提供)：芬威健康中心是波士顿领先的社区健康中心，从事艾滋病毒/艾滋病研究已有20多年，该中心建议建立芬威ATU，以便为感染艾滋病毒的青少年和高危青少年的艾滋病毒预防和治疗研究做出贡献。Fenway ATU是由艾滋病毒预防和治疗研究人员和社区卫生服务提供者组成的多学科合作机构，为大波士顿的高危青少年和感染艾滋病毒的青少年提供服务。芬威健康为1300多名青少年提供全面的医疗服务，包括：初级保健、行为健康、牙科、验光服务和全方位服务药房。芬威健康中心包括：安信大楼(医疗和行为健康诊所)、芬威研究所(研究、教育和政策中心)和西德尼·博鲁姆(青年和青少年中心)。在行为和生物医学艾滋病毒预防和治疗研究的领导者Kenneth H.Mayer医学博士、青少年艾滋病毒高级研究员Michelle Lally医学博士、备受尊敬的青少年和儿科医学提供者和专家Ralph Vetters医学博士以及艾滋病毒行为科学家Steven Safren博士的领导下，Fenway ATU准备为基于社区的行为翻译、预防、治疗性、杀微生物剂和疫苗试验的开发和实施做出贡献。该股由经验丰富的临床医生和社区教育工作者的长期工作人员组成，他们的社区参与创新办法在将难以接触到的人群纳入一系列研究研究并将其保留方面取得了成功。我们多样化的临床人群包括高危青年男性、女性和变性人，其中近60%来自有色人种社区。鉴于我们经验丰富的临床和研究人员，我们接触到难以接触到的人群，以及我们的综合服务协作，芬威ATU准备为改善青少年的研究机会和为艾滋病毒预防和治疗科学做出贡献。 相关性：艾滋病毒/艾滋病是大波士顿地区青年面临的一个重大公共卫生问题。这一申请证明了波士顿青少年试验股在艾滋病毒/艾滋病治疗和预防干预方面为青少年医学试验网络(ATN)作出贡献的能力。该股可以接触到通常很难接触到的、感染艾滋病毒风险较高的人群，并将运用我们识别和招募这些人群的技能，以推动预防未感染艾滋病毒和预防阳性的科学。

DESCRIPTION (provided by applicant): Fenway Health, the leading Boston community-health center which has conducted HIV/AIDS research for more than two decades, proposes to establish The Fenway ATU in order to contribute to HIV prevention and therapeutic research in HIV infected and at risk youth. The Fenway ATU is a multidisciplinary collaboration of HIV prevention and treatment researchers and community health providers serving at-risk and HIV- infected adolescents in greater Boston. Fenway Health provides comprehensive medical care to over 1,300 adolescents including: primary care, behavioral health, dental, optometry services and a full service pharmacy. Fenway Health is comprised of: the Ansin Building (a medical and behavioral health practice), The Fenway Institute (a center for research, education and policy) and Sidney Borum (a center for youth and adolescents). Led by Kenneth H. Mayer, MD, a leader in behavioral and biomedical HIV prevention and treatment research, Michelle Lally, MD a senior adolescent HIV researcher, Ralph Vetters, MD, a well- respected provider and specialist in Adolescent and Pediatric Medicine and Steven Safren, PhD, a HIV behavioral scientist, the Fenway ATU is prepared to contribute to the development and implementation of behavioral, community-based translational, prophylactic, therapeutic, microbicide and vaccine trials. The Unit comprises of a long-standing staff of experienced clinicians and community educators whose innovative approach to community engagement has garnered success in involving and retaining hard to reach populations into a spectrum of research studies. Our diverse clinical population includes at-risk young men, women and transgender identified individuals with almost 60% being from communities of color. Given our experienced clinical and research staff, our access to hard to reach populations and our integrated service collaborative, the Fenway ATU is prepared to make strong contributions to improving research access and contributing to the science of HIV prevention and treatment for youth. RELEVANCE: HIV/AIDS is a significant public health problem facing youth in the greater Boston area. This application demonstrates the capacity of Boston Adolescent Trials Unit to contribute to the Adolescent Medicine Trials Network (ATN) in the area of HIV/AIDS treatment and prevention interventions. The Unit has access to populations which are typically hard to reach and at increased risk for HIV acquisition and will implement our skills of identifying and recruiting these populations in order to advance the science of HIV prevention for uninfected and prevention for positives.