Fenway Community Health Center, Inc., Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

芬威社区健康中心有限公司站点联盟 - HIV/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心（UM2 临床试验可选）

• 批准号: 10709608
• 负责人: KENNETH H MAYER
• 金额: $ 43.61万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2029-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10709608
• 关键词: Address; Adolescent Medicine Trials Network; Age Years; Authorization documentation; Boston; Caring; Clinical Trials; Clinical Trials Design; Collaborations; Communication; Communities; Community Health Education; Conduct Clinical Trials; Contracts; County; Drops; Enrollment; Ensure; Epidemic; Federally Qualified Health Center; Funding; Goals; Grant; HIV; HIV Seropositivity; HIV/AIDS; Harm Reduction; Health; Health system; Housing; Human Resources; Infrastructure; Injecting drug user; Intervention; Investigational Drugs; Justice; Laboratories; Leadership; Legal; Massachusetts; Mediation; Medical; Monitor; Neighborhood Health Center; New England; New Hampshire; Pharmacy facility; Phase; Prevention; Primary Care; Process; Protocols documentation; Public Health; Research; Research Personnel; Research Priority; Research Project Grants; Resources; Risk; Schools; Sexual and Gender Minority Youth; Sexually Transmitted Diseases; Site; System; Work; Youth; authority; behavioral health; behavioral study; community engagement; design; improved; innovation; meetings; member; operation; participant retention; programs; recruit; screening; social health determinants; transmission process

ABSTRACT The Fenway Institute The Fenway Site Consortium (FSC) is designed to support, as one of the Site Consortiums, the application of Westat to serve as the Operations and Coordinating Center (OCC) in the next funding cycle of the Adolescent Trials Network (ATN) (RFA HD 23-021). The FSC will be based at The Fenway Institute (TFI) of Fenway Health (FH), a Federally Qualified Health Center in downtown Boston, Suffolk County. The long- term objectives of this proposal are to conduct the research projects identified by the ATN Executive Committee (EC) and Scientific Leadership Center (SLC), and optimize recruitment, monitoring, and retention of HIV- positive and at-risk youth into clinical trials designed to improve their health and to decrease HIV transmission and acquisition. To facilitate this process, the FSC will include other key FH programs, including the health center, which provides primary care for more than 9,500 youth 24 years of age and younger, with a focus on the affiliated Sidney Borum Health Center, which specializes in the care of sexual and gender minority youth, and the Public Health Programs that include programs focusing on health system navigation, drop in HIV/sexually transmitted infection (STI) screening, harm reduction programs for PWID, and programs addressing social determinants of health (e.g., housing and legal support). Additionally, we will utilize our grants management and contract negotiation teams to ensure optimal execution of all logistical and budgetary aspects of the grant. A primary member of the consortium will be JRI Health, which administers multiple programs for HIV-infected and at-risk youth in Boston and throughout Southern New England, including Providence, Worchester, and Southern New Hampshire. Other consortium members will include the Boston Public Health Commission, Boston Public Schools, the Massachusetts Department of Public Health (DPH), and collaborators in other local programs serving HIV-positive and at-risk youth. These partnerships will enable us to meet the proposed research goals of the SLC. In this project, we aim to: (1) Convene regular meetings of key consortium members to discuss new and ongoing protocols, to solicit their input regarding best practices for recruitment, community engagement, and participant retention, and for community education; (2) Convene a youth community advisory board (YCAB), which will provide input into youth priorities related to the work of the ATN, and guidance regarding best practices for community engagement and education; (3) Ensure optimal communication between local members of the FSC and the OCC and scientific leadership through routine meetings of local consortium members and engagement of consortium members in meetings convened by the OCC; (4) Actively participate in all relevant ATN activities, including providing site representatives to governance committees of the ATN, and site investigators to represent the FSC on ATN protocols.

芬威学院摘要 芬威现场联合体(FSC)旨在支持作为现场联合体之一的 Westat将在下一个青少年资助周期中担任运营和协调中心(OCC) 试验网络(ATN)(RFA HD 23-021)。FSC的总部将设在芬威的芬威研究所(TFI) Health(FH)，位于萨福克县波士顿市中心的一家联邦合格健康中心。长期的 这项提案的目标是开展ATN执行委员会确定的研究项目 (EC)和科学领导中心(SLC)，并优化艾滋病毒的招募、监测和保留- 将阳性和高危青年纳入旨在改善他们健康和减少艾滋病毒传播的临床试验 和收购。为了促进这一进程，FSC将包括其他关键的FH计划，包括健康 该中心为9,500多名24岁及以下的青年提供初级保健，重点是 附属的西德尼·博鲁姆健康中心专门照顾性和性别少数族裔青年， 以及公共卫生计划，其中包括侧重于医疗系统导航的计划，请访问 艾滋病毒/性传播感染(STI)筛查、针对PWID的减少危害计划和计划 解决健康的社会决定因素(例如住房和法律支持)。此外，我们将利用我们的 授予管理和合同谈判团队，以确保所有后勤和预算的最佳执行 赠款的各个方面。该财团的主要成员将是JRI Health，该公司管理着 针对波士顿和整个新英格兰南部感染艾滋病毒和高危青年的方案，包括 普罗维登斯、伍切斯特和新罕布夏州南部。其他财团成员将包括波士顿 公共卫生委员会、波士顿公立学校、马萨诸塞州公共卫生部(DPH)以及 为艾滋病毒阳性和高危青年提供服务的其他地方项目的合作者。这些伙伴关系将使我们能够 以达到小岛屿发展中国家拟议的研究目标。在这个项目中，我们的目标是：(1)召开定期会议 主要联盟成员讨论新的和正在进行的议定书，以征求他们对最佳做法的意见 用于招募、社区参与和保留参与者，以及社区教育；(2)召集 青年社区咨询委员会(YCAB)，该委员会将为青年优先事项提供意见，这些优先事项与青年的工作有关 ATN和关于社区参与和教育的最佳做法的指导；(3)确保最佳 FSC和OCC当地成员之间的沟通和通过常规的科学领导 当地财团成员的会议以及财团成员参与由 OCC；(4)积极参与ATN的所有相关活动，包括提供现场代表 ATN的治理委员会和现场调查员代表FSC制定ATN协议。