Dynamic Perturbation Training System for ACL Rehabilitation

ACL 康复动态扰动训练系统

• 批准号: 8441487
• 负责人: JEFFREY J. CHU
• 金额: $ 57.09万
• 依托单位: SIMBEX, LLC
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8441487
• 关键词: Address; Adopted; Algorithms; Anterior Cruciate Ligament; Cartilage; Clinical; Clinical Trials; Computer software; Contralateral; Cost Analysis; Data; Degenerative polyarthritis; Delaware; Development; Devices; Equilibrium; Equipment; Feedback; Female; Funding; Goals; Health Care Costs; Impairment; Individual; Injury; Intervention; Joints; Knee; Knee Osteoarthritis; Laboratories; Lateral; Lead; Life; Limb structure; Manuals; Meniscus structure of joint; Methods; Metric; Motion; Operative Surgical Procedures; Outcome; Patients; Performance; Phase; Pilot Projects; Population; Protocols documentation; Publishing; Rehabilitation Outcome; Rehabilitation therapy; Research; Research Methodology; Running; Simulate; Small Business Innovation Research Grant; Sports; Surface; System; Technology; Testing; Therapeutic; Time; Training; Translating; Translations; United States National Institutes of Health; Universities; Validation; Walking; Woman; anterior cruciate ligament reconstruction; anterior cruciate ligament rupture; base; clinical application; clinical practice; clinically relevant; commercialization; comparative effectiveness; cost effective; design; human subject; improved; injured; kinematics; ligament injury; male; man; meetings; model design; neuromuscular; novel; patient population; prevent; prototype; quadriceps muscle; strength training; user-friendly

DESCRIPTION (provided by applicant): Anterior cruciate ligament (ACL) injuries are a significant problem for athletes, and women in particular. Both surgical and non-surgical treatment options exist, with the ultimate goal of regaining joint stability, knee kinematics, and quadriceps strength compared to the uninjured contralateral limb to allow full return of function and activity level and to prevent additional injury to the cartilage and the meniscus in the knee which might lead to an increased likelihood of osteoarthritis (OA). Published research has demonstrated clinically relevant effects of perturbation of support surface training for both ACL-deficient and ACL-reconstructed populations for improving dynamic knee stability, particularly in females. The clinically available methods of delivering the desired perturbations are currently limited to static balance boards that are manually pushed or pulled by the physical therapist. These perturbations may not simulate real-life perturbations that would occur during walking or running. The Principal Objective of this Fast Track SBIR project is to develop and validate a cost-effective commercial product, ActiveStep-Sport", for providing task-specific, neuromuscular, dynamic perturbation training to improve outcomes for both conservative and surgical treatment of ACL injury (ACL), particularly in young athletes and women.

描述（由申请人提供）：前十字韧带 (ACL) 损伤对于运动员，尤其是女性来说是一个重大问题。手术和非手术治疗方案均存在，最终目标是与未受伤的对侧肢体相比，恢复关节稳定性、膝关节运动学和股四头肌力量，以完全恢复功能和活动水平，并防止膝关节软骨和半月板受到额外损伤，从而增加患骨关节炎 (OA) 的可能性。已发表的研究表明，对 ACL 缺陷和 ACL 重建人群的支撑表面扰动训练对于改善动态膝关节稳定性（尤其是女性）具有临床相关效果。目前临床上可用的提供所需扰动的方法仅限于由物理治疗师手动推或拉的静态平衡板。这些扰动可能无法模拟现实生活中行走或跑步期间发生的扰动。该 Fast Track SBIR 项目的主要目标是开发和验证一种具有成本效益的商业产品 ActiveStep-Sport，用于提供特定任务的神经肌肉动态扰动训练，以改善 ACL 损伤 (ACL) 保守治疗和手术治疗的结果，特别是年轻运动员和女性。