Prescription drugs misuse and risky sexual behaviors among YMSM in Philadelphia

费城 YMSM 中的处方药滥用和危险性行为

• 批准号: 8517076
• 负责人: Aleksandar Kecojevic
• 金额: $ 3.11万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8517076
• 关键词: Accounting; Address; Age; Alcohol or Other Drugs use; Alcohols; Anal Sex; Buffers; Chronic stress; Communities; Community Physician; Cross-Sectional Studies; Data; Depression and Suicide; Development; Dimensions; Drug Prescriptions; Drug abuse; Drug usage; Exhibits; Goals; HIV; HIV Infections; HIV risk; Health; Heterosexuals; Homelessness; Illicit Drugs; Individual; Knowledge; Life Experience; Literature; Masculine; Medical; Mental Health; Minority; Mission; Modeling; National Institute of Drug Abuse; Opioid; Pattern; Pharmaceutical Preparations; Philadelphia; Play; Policies; Policy Maker; Population; Public Health; Qualitative Research; Recruitment Activity; Reporting; Research; Research Methodology; Research Personnel; Risk; Risk Behaviors; Risk Factors; Risk-Taking; Role; Scientific Advances and Accomplishments; Sex Behavior; Sexual Health; Sexually Transmitted Diseases; Social Environment; Social support; Stress; Substance abuse problem; Testing; Time; Tobacco; Tranquilizing Agents; United States Dept. of Health and Human Services; Victimization; Violence; Work; Youth; adverse outcome; aged; bullying; cohort; college; design; evidence base; experience; health disparity; high risk sexual behavior; innovation; interest; member; men who have sex with men; minority health; misuse of prescription only drugs; peer; physical conditioning; pressure; prevent; racial discrimination; resilience; sexual minority; social; social norm; social stigma; stressor; theories; young adult

DESCRIPTION (provided by applicant): Non-medical use of prescription drugs (NMUPD), i.e. opioids, tranquilizers, or stimulants, is a serious and growing public health problem in the U.S. Most data on NMUPD among young adults is limited to the heterosexual college population while significant knowledge gaps exist regarding NMUPD among young men who have sex with men (YMSM). Given the well-established intersection of drug use and risky sexual behaviors and high rates of HIV infections in YMSM, the purpose of this study is to examine the relationship between these drugs and physical, sexual and psychological health of YMSM. YMSM have unique concerns for health risks, such as depression, suicide, bullying, victimization, homelessness, and homophobia, but little is known of their intersection with NMUPD. Many YMSM experience normative pressures that encourage risky behaviors. At the same time, some forms of social support and resilience may buffer against negative effects of stressors. Significant gaps exist in our understanding of how these factors relate to problematic patterns of NMUPD, and whether they modify engagement in risky sexual behaviors. The objective of this study is to contribute directly to our understanding of the social factors that influence NMUPD and risky sexual behaviors among YMSM. The long-term goal of the study is to guide public health practitioners towards developing strategies that will prevent negative effects of NMUPD on YMSM, including reducing disparities in rates of HIV infection among YMSM. The study will investigate the central hypothesis of a deleterious relationship between NMUPD and physical, sexual, and psychological health of YMSM. The central hypothesis will be tested by pursuing three specific aims: Aim 1: Determine patterns of NMUPD and risky sexual behavior among YMSM in Philadelphia; Aim 2: Determine the risk and protective factors contributing to NMUPD and risky sexual behavior among YMSM; Aim 3: Explore the social contexts of NMPUD. Aims 1 and 2 will be addressed by recruiting 190 YMSM ages 18-29 in Philadelphia who have recently misused prescription drugs. Aim 3 will be addressed by selecting a subsample of 25 YMSM for a qualitative study. This approach is innovative because it utilizes a conceptual framework that combines a minority stress model and theories of social norms, social support, and resilience; it focuses on a critical cohort of under-researched, hard-to-reach population; and it employs two research methodologies. The proposed research is significant because it is expected to advance and expand our understanding of the effects of an emerging phenomena (i.e., prescription drug misuse) on adverse consequences of sexual activity. It will also contribute to a better understanding of the role of social determinants on dug use and risky sexual behavior. Such knowledge may inform the development of evidence-based strategies that will prevent adverse health and psychological effects of NMUPD on YMSM and their communities in Philadelphia and elsewhere in the U.S.

DESCRIPTION (provided by applicant): Non-medical use of prescription drugs (NMUPD), i.e. opioids, tranquilizers, or stimulants, is a serious and growing public health problem in the U.S. Most data on NMUPD among young adults is limited to the heterosexual college population while significant knowledge gaps exist regarding NMUPD among young men who have sex with men (YMSM).鉴于毒品使用和危险的性行为和YMSM中艾滋病毒感染的高率的良好相交，本研究的目的是检查这些药物与YMSM的身体，性和心理健康之间的关系。 YMSM对健康风险有独特的关注，例如抑郁，自杀，欺凌，受害，无家可归和同性恋恐惧症，但对它们与NMUPD的交集知之甚少。许多YMSM经历了鼓励风险行为的规范压力。同时，某些形式的社会支持和韧性可能会缓冲压力源的负面影响。我们对这些因素如何与NMUPD有问题的模式以及它们是否改变了危险性行为行为的关系的理解存在很大的差距。这项研究的目的是直接为我们理解影响NMUPD的社会因素和YMSM中有风险的性行为。该研究的长期目标是指导公共卫生从业人员制定策略，以防止NMUPD对YMSM的负面影响，包括降低YMSM中HIV感染率的差异。该研究将研究NMUPD与YMSM的身体，性和心理健康之间有害关系的中心假设。中心假设将通过追求三个具体目标来检验：目标1：在费城YMSM中确定NMUPD的模式和风险的性行为；目标2：确定YMSM中有助于NMUPD和风险性行为的风险和保护因素；目标3：探索NMPUD的社会环境。 AIM 1和2将通过在费城招募190名YMSM 18-29岁的YMSM来解决，他们最近滥用处方药。 AIM 3将通过为定性研究选择25 YMSM的子样本来解决。这种方法具有创新性，因为它利用了一个概念框架，该概念框架结合了少数派压力模型和社会规范，社会支持和韧性的理论。它着重于研究不足，难以触及的人群的关键队列；它采用了两种研究方法。拟议的研究之所以重要，是因为它有望提高和扩展我们对新兴现象（即处方药滥用）对性活动不利后果的影响的理解。它还将有助于更好地理解社会决定因素在挖掘使用和风险性行为方面的作用。这些知识可能会为发展基于证据的策略的制定提供信息，这些策略将防止NMUPD对YMSM及其在费城及其其他地方的社区的不利影响和心理影响。