Adaptive Intervention Strategies: Advancing Research and Career Development

适应性干预策略：推进研究和职业发展

• 批准号: 8565213
• 负责人: Ken C WINTERS
• 金额: $ 16.55万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-15 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8565213
• 关键词: Abstinence; Address; Adherence; Adolescent; Affective; Behavior; Behavior Disorders; Behavior Therapy; Characteristics; Clinical; Clinical Investigator; Cognitive; Communities; Community Practice; DSM-IV; Data; Decision Making; Dependence; Development; Diagnostic and Statistical Manual; Drug usage; Effectiveness; Evidence based intervention; Eye; Funding; Genetic; Grant; Health; Hybrids; Individual; Intervention; Measures; Mentors; Modeling; Outcome; Parents; Participant; Pharmaceutical Preparations; Population; Prevention; Prevention Protocols; Prevention Research; Prevention approach; Prevention strategy; Preventive Intervention; Procedures; Program Effectiveness; Program Efficiency; Provider; Randomized; Research; Research Design; Research Personnel; Research Training; Schools; Science; Scientist; Services; Staging; Substance Use Disorder; Teenagers; Testing; Training; Universities; Youth; adolescent drug abuse; base; brief intervention; career; career development; community setting; design; dosage; experience; indicated prevention; intervention program; next generation; programs; public health relevance; research and development; response; responsible research conduct; satisfaction; skills; user-friendly

DESCRIPTION (provided by applicant): The purpose of the proposed K24 is to i) advance the research of the applicant in the study of personalized or adaptive indicated prevention strategies to address mild-moderate adolescent drug involvement and ii) mentor and train the next generation of scientists in adolescent SUDs and related behavioral disorders health who will conduct research from a preventive intervention perspective. The mentoring program will train four, already identified, early career, clinically-oriented researchers in advanced topics in prevention science and facilitate their expertise in developing and testing of personalized or adaptive intervention strategies (AIS) within an indicated prevention model. AIS are empirically-based decision rules in which the intervention plan (type, dosage, or sequence of components) offered to participants is individualized based on participants' response to the intervention (i.e. primary tailoring variable) and/or individual characteristics assessed prior to intervention (i.e., secondary tailoring variables). Furthermore, training and research will focus on mild- moderate drug using teenagers (abuse as defined by DSM-IV or mild substance use disorder as defined by proposed DSM-5), with the aim of abstinence or halting progression to dependence.

描述（由申请人提供）：拟定K24的目的是i）推进申请人在个性化或适应性指示预防策略研究中的研究，以解决轻度-中度青少年药物参与问题，ii）指导和培训下一代青少年SUD和相关行为障碍健康科学家，他们将从预防干预的角度进行研究。该指导计划将培训四名已经确定的早期职业，面向临床的研究人员，研究预防科学的高级主题，并促进他们在指定预防模型中开发和测试个性化或适应性干预策略（AIS）的专业知识。AIS是基于实践的决策规则，其中提供给参与者的干预计划（类型、剂量或组分顺序）基于参与者对干预的响应（即，主要定制变量）和/或在干预之前评估的个体特征（即， 二次剪裁变量）。此外，培训和研究将侧重于轻度至中度吸毒的青少年（《精神疾病诊断和统计手册》第四版所界定的滥用或拟议的《精神疾病诊断和统计手册》第五版所界定的轻度药物使用障碍），目的是戒除或阻止发展为依赖。