Clinical and Preclinical Models in Drug Abuse: Training and Development

描述（由申请人提供）：本高级科学家研究和导师奖（K05）申请的目的是允许我（Richard W. Foltin, Ph.D.）保护时间，以便我可以继续指导初级教师。通过这种方式，我将与初级教师分享我从导师那里学到的很多东西，反过来，我从初级教师那里学到的东西也会使我的研究受益。具体来说，我将与希望将类似的强有力的方法应用于其专业领域的初级同事分享我在难以建模的领域（复发、药物对自我给药的假定影响、估计行为强化价值）进行控制良好的实验室研究的经验。目标1。研究：目的1。使用非人类灵长类动物和有吸毒经验的人类志愿者的药物滥用实验室模型，维持积极的研究项目。我的积极支持一直在为初级教师提供研究机会和工资支持方面发挥着作用。我有2个活跃的R01和2个未决的R01提交，将用于支持我的研究和提供培训机会。目标2。通过整合我在神经心理学、磁共振成像、饮食失调和老年精神病学方面指导的初级教师的专业知识，扩大我的研究兴趣。目标2。训练：目标1。继续成为我们研究小组中更资深的教师的宝贵资源，自从他们完成博士后研究以来，我一直在指导他们。目标2。帮助我指导的那些获得K奖的人，他们现在已经4、5岁了，正在向独立状态过渡。目标3。为我指导的那些获得K奖的头几年的个人提供指导。目标4。在部门事务中保持清晰的形象，这样我就可以成为药物滥用研究和初级教员需求的倡导者。在接下来的5年里，我有足够的指导责任来解释我的指导工作。一般来说，我指导的初级教师将首先进行项目，这些项目将作为我的r01之一的一部分获得资助，然后在提交K申请之前，在可能的情况下为试点研究申请部门资金。这种模式在过去很有效，将用于为初级教师开发新的K奖。

DESCRIPTION (provided by applicant): The purpose of this Senior Scientist Research and Mentorship Award (K05) application is to allow me (Richard W. Foltin, Ph.D.) protected time so that I may continue to mentor junior faculty. In this way I will share with the junior faculty much of what I learned from my mentors and in turn have my research benefit from what I learn from the junior faculty. Specifically, I will share my experience in conducting well-controlled, laboratory- based studies in areas that are difficult to model (relapse, putative medication effects on drug self- administration, estimating reinforcing values of behavior) with junior colleagues who are hoping to bring similar powerful methodologies to bear on their areas of expertise. Goal 1. Research: Aim 1. Maintain active research programs using laboratory models of drug abuse in non-human primates and drug-experienced human volunteers. My active support has always played a role in providing both research opportunities and salary support for junior faculty. I have 2 active R01s and 2 pending R01 submissions that will be used to support my research and provide training opportunities. Aim 2. Expand my research interests by incorporating the expertise of junior faculty I am mentoring in neuropsychology, magnetic resonance imaging, eating disorders and geriatric psychiatry. Goal 2. Training: Aim 1. Continue to be a valuable resource to the more senior faculty in our research group whom I have mentored since they completed their postdoctoral fellowships. Aim 2. Help the individuals whom I mentored on their K awards who are in their 4th and 5th years and now transitioning to independent status. Aim 3. Provide guidance to the individuals whom I mentor that are in the first several years of their K awards. Aim 4. Keep a discernible profile in departmental affairs so that I can be an advocate for drug abuse research and the needs of junior faculty. I have sufficient mentoring responsibilities to account for my mentoring effort over the next 5 years. Generally the junior faculty I mentor will first conduct projects that will be funded as part of one of my R01s, and then apply for divisional funds for pilot studies where possible prior to submitting a K application. This model has worked well in the past and will be used to develop new K awards for junior faculty.