Administrative Core

项目总结(见说明)： 核心A管理核心的总体目标是加强该计划项目赠款(PPG)的科学和业务协同作用，并支持所有与计划相关的活动以及项目和核心调查人员和工作人员。核心A在PPG联合项目主任的指导下，是负责优化整个PPG的科学和业务产出的行政总括。核心A将承担最终责任，确保在四个项目和本方案规划中的其他四个核心内和之间实现资源的协同增效和有效管理。由于PPG团队中的科学家代表了多学科、培训和经验，因此极有可能取得具有重要临床分支的生产性科学成果。因此，核心A有责任建立一个基础设施，要求这种协同效应和产出取得成果。具体目标是：1)通过调查人员、合作者-顾问和顾问之间的科学交流、交叉协作和沟通，促进项目和核心的一体化，并最大限度地将成果传播给科学界和医学界；2)监测进展情况，协调项目小组的业务和行政方面，最大限度地提高效率。CORE A将作为与国家卫生研究院和亨利·福特卫生系统(HFHS)、佐治亚医学院(MCG)、加州大学旧金山分校(UCSF)和密歇根大学的研究管理、赠款会计和其他行政办公室的接口。它还将协调外部咨询委员会的活动，并组织科学和业务会议(电话会议和面谈)。监督和鼓励沟通、质量和研究成果(主要是已发表的手稿)将是核心A促进科学和业务协同作用、有效和及时传播研究结果以及有效管理工作人员和资金的主要努力。

PROJECT SUMMARY (See instructions): The overall objective of the Core A Administrative Core is to potentiate the scientific and operational synergism of this Program Project Grant (PPG) and to support all program-related activities and Project and Core investigators and staff. Core A, under the direction of the PPG Co-Program Directors, is the administrative umbrella responsible for optimizing scientific and operational output across the PPG. Core A will have the ultimate responsibility of assuring that synergy and efficient management of resources exists within and across the four Projects and the other four Cores in this PPG. A productive scientific yield with important clinical ramifications is highly probable because of the multiple disciplines, training and experience represented by the scientists on this PPG team. Therefore, it is the responsibility of Core A to establish an infrastructure that will demand that this synergy and yield come to fruition. The Specific Aims are: 1) to foster integration of the PPG Projects and Cores through scientific interchange, cross-collaboration and communication among the investigators, collaborator-consultants, and advisors, and to maximize the dissemination of results to the scientific and medical communities; and 2) to monitor progress and coordinate the operational and administrative facets of the PPG, maximizing efficiencies. Core A will act as an interface with the National Institutes of Health and the research administrations, grant accounting and other administrative offices of the Henry Ford Health System (HFHS), Medical College of Georgia (MCG), University of California-San Francisco (UCSF) and the University of Michigan. It will also coordinate the activities of the External Advisory Committee and organize scientific and operational meetings (conference calls and in-person). Oversight and encouragement of communication, quality, and research output (primarily published manuscripts) will be the key efforts of Core A to promote scientific and operational synergy, an effective and timely dissemination of findings, and effective stewardship over staff and funds.