Induction Of Natural T-Regulatory Cells By Thymic Dendritic Cell Populations

胸腺树突状细胞群诱导天然 T 调节细胞

• 批准号: nhmrc : 516733
• 负责人: Prof Li Wu
• 金额: $ 27.59万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/induction-natural-t-cell-populations/83105
• 关键词: Induction; Natural; Regulatory; Cells; Thymic

In this study, we will determine the roles of the antigen presenting cells, namely denderitic cells, in the induction of T-regulatory cell (T-reg) developemnt in the thymus. T-reg cells play important roles in controlling the development of autoimmunity. This study will help to understand the possible causes of autoimmune diseases and to develop new treatments for these diseases.

在这项研究中，我们将确定抗原提呈细胞，即脱落细胞，在诱导胸腺发育的T调节细胞(T-REG)中所起的作用。T-reg细胞在控制自身免疫的发生发展中起着重要作用。这项研究将有助于了解自身免疫性疾病的可能原因，并为这些疾病开发新的治疗方法。