The transcriptional control of the dendritic cell lineages

免疫系统可以区分入侵的微生物和人体自身的组织。树突状细胞专门用于在感染的情况下警告免疫系统。在这个项目中，我们的目标是了解树突状细胞是如何产生的，以及它们如何控制免疫反应。我们将通过使用最先进的基因组技术来描述树突状细胞的遗传程序来实现这一目标。我们希望，这些知识将使我们能够更好地利用免疫反应的情况下，如疫苗接种。

The immune system can discriminate between invading microorganisms and the body's own tissues. Dendritic cells are specialised to alert the immune system in the case of infection. In this project we aim to understand how dendritic cells are generated and how they function to control the immune response. We will achieve this aim by using state of the art genomic technologies to describe the genetic programme of dendritic cells. We hope that this knowledge will enable us to better harness the immune response in situations such as vaccination.