Stimulating Young Neuroscientists And Physiologists in Science Education (S.Y.N.A

激励年轻神经科学家和生理学家进行科学教育（S.Y.N.A

• 批准号: 8319333
• 负责人: Jared Jackson
• 金额: $ 25.74万
• 依托单位: IS3D, LLC
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8319333
• 关键词: 3-Dimensional; Accounting; Action Potentials; Address; Alzheimer' s Disease; Area; Autistic Disorder; Brain; Brain region; Case Study; Case-Control Studies; Cessation of life; Chemistry; Collaborations; Computer software; Consultations; Data Reporting; Diagnosis; Disease; Economically Deprived Population; Education; Educational Materials; Educational process of instructing; Educational workshop; Ensure; Face; Feedback; Functional Magnetic Resonance Imaging; Goals; Health; Hearing; Imaging technology; Industry; Knowledge; Learning; Left; Market Research; Marketing; Mathematics; Measurement; Membrane Potentials; Mental Depression; Microscopic; Minority; Monitor; Motor; Movement; Names; Nervous System Physiology; Neurologic; Neurology; Neurons; Neurosciences; Neurosciences Research; Neurotransmitters; Parkinson Disease; Patients; Phase; Physics; Production; Reporting; Resources; Role; Route; STEM field; Schools; Science; Scientist; Sensory; Smell Perception; Solutions; Staging; Structure; Students; Symptoms; Synapses; Taste Perception; Teaching Materials; Technology; Testing; Time; Touch sensation; Travel; Underrepresented Minority; United States; United States National Institutes of Health; Video Games; Vision; Work; animation; artist; base; career; combat; demographics; design; experience; girls; high school; inner city; innovation; innovative technologies; interest; meetings; metropolitan; middle school; nervous system disorder; neurotransmission; pressure; programs; prototype; receptor; response; science education; success; teacher; three-dimensional modeling

DESCRIPTION (provided by applicant): The long-term aim of this project is to develop a revolutionary way to engage middle and high school students in neuroscience and thereby increase their interest in possible careers in this area. This will be achieved by creating highly interactive and immersive educational materials that make maximal use of today's 3D modeling and videogame technologies. Using the brain of a 3D character, the students will first observe and then control, the activity levels in the regions of the brain that are responsible for sight, hearing, smell, touch, taste and movement. In doing so, they will learn how structure and function in the brain are related, how the functions of the brain are compartmentalized, and how imaging technologies, such as functional MRI, are used to monitor changes in brain activities in people. Having explored the brain at the macroscopic level, the students will then enter the microscopic world of neuroscience where they will explore synapses in a "patient" with neurological symptoms. In this case study, the students will travel into a 3D model of the patient's brain where they will observe activities within the synapses, take measurements about the production, release and interactions of neurotransmitters with their receptors, compare these measurements with those in normal synapses, develop a hypothesis to account for any abnormalities identified, test that hypothesis by applying specific treatments, and then compare responses to those treatments to determine if their hypothesis was correct. In doing so, the students will leave their usual passive roles as 'receivers of information' in the classroom to take active roles of neuroscientists in search of a diagnosis and treatment for a real-world disease. This project will address the growing problem of lack of diversity in the science work force by partnering with schools with high percentages of economically disadvantaged underrepresented minority students, and an all- girls school in Atlanta. Not only will these students help at the outset of the project by identifying the neuroscience topics students find most difficult to understand, but they will also be directly involved in field- testing the educational materials in their formative stages. In the latter component of this Phase I project, the students will provide critical input into the design and presentation of the neurology case study to ensure that it 'speaks' to two demographics that currently are underrepresented in science in the US.

描述（由申请人提供）：该项目的长期目的是开发一种革命性的方式来吸引中学和高中生的神经科学，从而增加他们对这一领域可能职业的兴趣。这将通过创建高度互动和沉浸式的教育材料来实现，从而最大程度地利用当今的3D建模和电子游戏技术。使用3D角色的大脑，学生将首先观察，然后控制大脑区域的活动水平，负责视觉，听力，气味，触摸，味觉和运动。这样一来，他们将学习大脑中的结构和功能如何相关，大脑的功能如何被隔离，以及如何使用成像技术（例如功能性MRI）来监视人们大脑活动的变化。在探索宏观水平的大脑之后，学生将进入神经科学的微观世界，在那里他们将在具有神经系统症状的“患者”中探索突触。在此案例研究中，学生将进入患者大脑的3D模型，在那里观察突触中的活动，对神经递质与受体的生产，释放和相互作用进行测量，将这些测量与正常突触中的测量值进行比较，从而将假设提出确定的鉴定，然后确定的鉴定，并确定这些假设，并确定该假设，并确定该假设，以确定该假设，并确定该假设，并确定假设的措施，以便将这些假设与这些假设相比，是否可以通过这些假设来确定假设，并考虑到这些假设，并将其确定。 正确的。这样一来，学生将在课堂上留下通常的被动角色，作为“信息接收者”，以扮演神经科学家的积极作用，以寻找现实世界中疾病的诊断和治疗。该项目将通过与拥有高百分比的经济不利人数不足的少数族裔学生以及亚特兰大的全女子学校的学校合作，解决科学劳动力缺乏多样性的问题。这些学生不仅可以通过识别学生发现最难理解的神经科学主题来提供帮助，而且他们还将直接参与现场测试，以在其形成阶段进行教育材料。在该阶段项目的后期部分中，学生将对神经病学案例研究的设计和介绍提供关键的意见，以确保它对目前在美国科学中不足的两个人口统计学“说话”。