Online Respondent-Driven Sampling & Data Collection for Men who have Sex with Men

在线受访者驱动抽样

• 批准号: 8208974
• 负责人: Edward William White
• 金额: $ 20.91万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8208974
• 关键词: AIDS prevention; Acquaintances; Acute; Address; Alcohol or Other Drugs use; Behavior; Behavioral; Biological; Biometry; Chlamydia; Collection; Color; Data; Data Collection; Diagnostic; Diagnostic tests; Effectiveness; Electronic Mail; Epidemiologic Studies; Goals; Gonorrhea; Growth; HIV; Home environment; Hour; Human; Human immunodeficiency virus test; Incidence; Individual; Infection; Information Systems; Information Technology; Internet; Interview; Investigation; Knowledge; Length; Link; Mails; Measures; Method Acceptability; Methodology; Methods; Paper; Participant; Pilot Projects; Population; Population Analysis; Population Study; Prevalence; Prevention Research; Preventive Intervention; Probability Samples; Productivity; Protocols documentation; Public Health; Recording of previous events; Recruitment Activity; Relative (related person); Reliance; Reporting; Research; Research Personnel; Respondent; Rewards; Risk; Risk Behaviors; Sampling; Science; Security Measures; Seeds; Services; Sexually Transmitted Diseases; Site; Specific qualifier value; Specimen; Surveys; Syphilis; System; Target Populations; Techniques; Telephone; Test Result; Testing; Time; Translating; Weight; base; design; improved; innovation; interest; meetings; member; men; men who have sex with men; method development; operation; peer; programs; public health relevance; sample collection; sex; sexually active; volunteer; web site

DESCRIPTION (provided by applicant): This application addresses PA-10-069. The development of methods to produce less-biased, more generalizable samples of men who have sex with men (MSM) is vital to HIV prevention science. The proposed study will assess the feasibility of improving representativeness of samples of MSM recruited online, a population at acute risk for sexually transmitted infections. While the existing network of Internet-using MSM (IUMSM) is wide ranging, densely connected and diverse, studies of this population have been limited to convenience and snowball samples that over-represent heavy Internet users. This project would employ respondent-driven sampling (RDS) a chain-referral method that starts by selecting of initial respondents (seeds) who recruit peers (other members of the target population) as additional respondents. Those new participants in turn recruit others, forming recruitment chains. RDS is an adaptive sampling technique designed to overcome a major limitation of generalizability, over-sampling population members with greater numbers of peer ties and hence greater likelihood of recruitment. It accomplishes this by weighting observations based on each participant's reported number of acquaintances in the target population that he himself could recruit. To date, RDS among MSM has been conducted using face-to-face interviews. While RDS has demonstrated effectiveness in recruiting MSM and allowing collection of behavioral data and diagnostic specimens for sexually transmitted infection (STI) testing, restricted chain lengths and low recruitment productivity have limited sample representativeness. By permitting participants to select peers for referral from online contacts, and refer those peers to the study online and to collect data via a website, on-line respondent driven sampling (ORS) would considerably ease both referral and participation relative to reliance on presentation at a physical site. ORS has the potential to produce longer referral-chains that penetrate more broadly across the population of interest, thus increasing sample representativeness. Recruitment and data collection can plausibly be accomplished entirely online, but collection of the biological specimens often obtained using RDS necessitates innovation. Therefore the proposed study will determine the feasibility of obtaining though postal delivery home-collected biological specimens for STI testing from a subset of the IUMSM recruited via ORS. The project will pilot ORS among MSM, a population characterized by a high degree of online interconnectedness, to assess the acceptability to the target population of (a) referring peers online, (b) collection of behavioral data from peer-referred participants via a website, (c) the feasibility of obtaining biological specimens. Information systems will feature stringent security measures put into place by Yale Information and Technology Services in accordance with the Yale Human Investigation Committee. PUBLIC HEALTH RELEVANCE: Improved sampling methods for IUMSM who use the Internet will serve three purposes: 1) better representativeness of IUMSM in epidemiological studies, 2) more generalizable inference in studies conducted among IUMSM, and 3) more informed behavioral data and potentially behavioral surveillance for prevention interventions targeting IUMSM. The proposed project will a) assess the ability of ORS to recruit IUMSM, b) determine the degree to which ORS meets criteria for representativeness and c) investigate the feasibility of obtaining biological specimens from ORS. It will lay the groundwork for a number of much-needed measures the prevalence of risk behavior and infection, and more valid and generalizable correlates of behaviors that can transmit STIs, among IUMSM.

描述（由申请人提供）：此申请地址PA-10-069。开发与男性发生性关系的男性（MSM）的方法的开发对艾滋病毒预防科学至关重要。拟议的研究将评估提高在线招募的MSM样本的代表性的可行性，这是对性传播感染的急性风险的人群。虽然现有的Internet使用MSM（IUMSM）网络范围广泛，连接和多样化，但对该人群的研究仅限于过度代表沉重的互联网用户的便利性和雪球样本。该项目将采用受访者驱动的抽样（RDS）一种链条推荐方法，该方法首先选择了招募同伴（目标人群的其他成员）作为其他受访者的初始受访者（种子）。这些新参与者反过来招募了他人，形成了招聘链。 RDS是一种自适应抽样技术，旨在克服对普遍性的主要局限性，过度采样的人群成员具有更多的同伴关系，从而更大的招募可能性。它通过根据每个参与者所报告的目标人群中报告的熟人数量来加权观察来实现这一目标。迄今为止，使用面对面的访谈进行了MSM中的RD。尽管RDS在招募MSM方面表现出了有效性，并允许收集性传播感染（STI）测试的行为数据和诊断标本，但受限的链长度和低招聘生产力的样本代表性有限。通过允许参与者从在线联系人中选择同行进行推荐，并将这些同龄人推荐到在线研究并通过网站收集数据，在线受访者驱动的采样（ORS）将相对于在物理站点上的依赖依赖依赖的依赖来轻松推荐和参与。 ORS有可能产生更长的转介链，这些链在感兴趣的人群中更广泛地穿透，从而提高样本的代表性。招聘和数据收集可以完全在线完成，但是通常使用RDS获得的生物标本的收集需要创新。因此，拟议的研究将确定从通过ORS募集的IUMSM的子集获得邮政递送家庭收集的生物学测试的可行性。该项目将在MSM之间进行试验，该项目以高度在线相互联系的特征，以评估（a）在线转介同伴的目标人群的可接受性，（b）通过网站收集从同伴转介参与者的行为数据，（c）获得生物学标本的可行性。信息系统将根据耶鲁大学人类调查委员会采取耶鲁大学信息和技术服务采取严格的安全措施。 公共卫生相关性：使用Internet的IUMSM的改进的抽样方法将有三个目的：1）在流行病学研究中更好地代表IUMSM，2）在IUMSM中进行的研究中更具普遍的推断，以及3）3）更明智的行为数据和对预防IMSMSMSMSMSM的潜在行为监测。拟议的项目将a）评估OR募集IUMSM的能力，b）确定ORS符合代表性标准的程度，c）研究从ORS获得生物标本的可行性。它将为许多急需的衡量风险行为和感染的率，以及在IUMSM之间传播性传播性传播性传播性传播性传播的行为的更为有效和可概括的相关性的基础。