Environmental Statistics and Biostatistics Core

环境统计与生物信息学核心 摘要 环境统计和生物信息学核心（ESBC）提供了广泛的 支持生物统计学、统计遗传学和基因组学、生物信息学和数据科学 对于与哈佛陈-NIEHS环境中心有关的调查人员来说， 健康在其他几个专门领域也提供援助，包括 环境流行病学和时空统计模型 参考数据。除了设计和分析支持，核心教职员工建议 研究人员的原则以及统计和计算工具， 科学，包括数据管理，大规模研究计算基础设施， 分析管道。此外，核心成员还为教师、研究生和 学生和研究员从事与中心有关的项目。核心教师和研究人员 从事与任务相关的方法研究，以问题为动力， 方法上的挑战，向中心成员提供免费软件， 更广泛的环境健康社区。有了这个核心，我们可以提供 与环境卫生问题特别相关的专门服务，例如 统计基因组学和生物信息学。它也给了我们必要的支持， 提供教育活动，如与（初级）研究者进行1：1的单独会议， 处理共同问题的重点工作组，并举行相关研讨会。 我们能够利用我们的中心支持与大学资源，以最大限度地提高我们的 为中心成员服务。

ENIRONMENTAL STATISTICS AND BIOINFORMATICS CORE ABSTRACT The Environmental Statistics and Bioinformatics Core (ESBC) provides a wide range of support in biostatistics, statistical genetics and genomics, bioinformatics, and data science for investigators associated with the Harvard Chan-NIEHS Center for Environmental Health. Assistance is also available in several other specialized areas including environmental epidemiology and statistical modeling of spatially and temporally referenced data. In addition to design and analysis support, Core faculty and staff advise investigators on principles as well as statistical and computational tools for reproducible science, including data management, large-scale research computing infrastructure, and analysis pipelines. Further, Core members provide statistical training for faculty, graduate students, and fellows working on Center-related projects. Core faculty and researchers engage in mission-related methodological research motivated by questions and methodological challenges, providing freely available software to Center members and the broader environmental health community. Having this Core enables us to provide specialized services particularly relevant to environmental health issues, such as statistical genomics and bioinformatics. It also gives us the necessary support to be able to offer educational activities such as 1:1 individual meetings with (junior) investigators, focused working groups that tackle common problems, and holding relevant seminars. We are able to leverage our Center support with University resources to maximize our services to Center members.