Biostatistics and Bioinformatics Shared Resource

生物统计学和生物信息学共享资源 (BBSR) 提供 生物统计和生物信息学的领导和对癌症中心内研究的支持。 BBSR 在癌症相关研究的设计和分析中发挥着关键作用，包括临床试验， 流行病学研究和基于实验室的研究。 BBSR 提供全方位的生物统计 服务，包括研究设计、样本量计算、数据分析和解释、方案审查、 和新统计方法的开发。 BBSR 还为癌症研究人员提供支持 存储、访问和分析大规模基因组、蛋白质组、临床、基于图像和系统生物学 该资源的总体目标是提供：（1）生物统计和生物信息学支持 癌症中心研究人员通过服务和协作活动； (2)统计运用培训 软件和生物统计方法，通过定期短期课程和一对一会议以及技术 为癌症中心成员和寻求使用的相关科学家提供指导和技术背景 基于癌症的生物医学研究中的并行超级计算和数据库硬件和软件； (3) 开发新的生物统计和生物信息方法以加强癌症中心的研究项目； (4) 传播能力，通过继续开发我们的网站来识别 提供人员和服务，以便更广泛地了解生物统计和生物信息学支持 可供癌症中心研究人员使用。爱德华·J·贝德里克博士是资源总监。苏珊·R。 阿特拉斯博士和克里斯汀·斯蒂德利博士是生物信息学资源的联合主任， 分别是生物统计学。 Bedrick 博士在生物统计学领域拥有超过 20 年的经验。 Atlas 博士已超过 20 年 科学计算和生物信息学方面的经验。 Stidley博士支持大型肺癌研究 和 SEER 的努力。该资源包括八名教职员工和科研人员，涉及广泛的领域 专业知识。自 2005 年以来，癌症中心成员与以下机构合作发表了 40 多篇文章 资源教师和工作人员。资源成员是 11 项经过同行评审的校外资助项目的共同研究员 与癌症中心成员合作，有几个待定。 30 多名癌症中心成员代表所有 4 个研究计划正在广泛利用该资源。

The Biostatistics and Biolnformatics Shared Resource (BBSR) provides biostatistical and bioinformatics leadership and support for research within the Cancer Center. The BBSR plays a critical role in the design and analysis of cancer related investigations, including clinical trials, epidemiological studies, and laboratory-based studies. The BBSR provides a full range of biostatistical services, including study design, sample size calculations, data analysis and interpretation, protocol reviews, and development of novel statistical methodologies. The BBSR also provides support for cancer researchers to store, access, and analyze large-scale genomic, proteomic, clinical, image-based, and systems biology datasets.The overall goals of the Resource are to provide: (1) biostatistical and bioinformatics support to Cancer Center researchers through service and collaborative activities; (2) training in the use of statistical software and biostatistical methods, through regular short courses and one-on-one sessions, and technical guidance and technology background to Cancer Center members and associated scientists seeking to use parallel supercomputing and database hardware and software in cancer-based biomedical research; (3) development of novel biostatistical and bioinformatic methods to enhance Cancer Center research projects; and (4) dissemination of capabilities, by continuing with the development of our website that identifies personnel and services provided to allow wider knowledge of the biostatistical and bioinformatics support available to Cancer Center investigators. Edward J. Bedrick, Ph.D. is Director of the Resource. Susan R. Atlas, Ph.D, and Christine Stidley, Ph.D. are Co-Directors of the Resource for bioinformatics and biostatistics, resectively. Dr. Bedrick has > 20 years experience in biostatistics. Dr. Atlas has > 20 years experience in scientific computing and bioinformatics. Dr. Stidley supports the large lung cancer research and SEER efforts. The Resource includes eight faculty and scientific staff, with a broad range of areas of expertise. Since 2005, Cancer Center members published more than 40 articles in collaboration with Resource faculty and staff. Resource members are co-investigators on 11 peer-reviewed extra-mural grants with Cancer Center members with several pending. More than 30 Cancer Center members representing all 4 Research Programs are making extensive use ofthe Resource.