HIV Risk Among Racially-Diverse, Minority Youth: Alcohol and Partner Selection

描述(由申请者提供)：本申请请求获得NIAAA指导研究科学家发展奖(K01)，授予Stephanie Staras博士，以开发一项HIV预防研究计划，重点关注少数族裔青少年中事件级别的饮酒(即性行为前2小时内饮酒)和性伴侣选择的交集。为了完成从传染病流行病学到与酒精相关的艾滋病毒预防的过渡，斯塔亚斯博士需要有保护的时间来提高在青少年中开发和评估与酒精有关的艾滋病毒预防干预措施的技能。Staras博士的职业发展目标是：(1)提高对酒精使用和艾滋病毒在青少年中传播的理论框架的了解；(2)加强在少数族裔青少年中进行与酒精相关的艾滋病毒预防干预所特别需要的研究技能；(3)提高对艾滋病毒预防研究的伦理行为的理解；以及(4)启动一项独立的艾滋病毒预防研究计划，重点关注事件级别的酒精使用和伴侣选择。她将通过完成与导师的指导学习，参与课程作业和研讨会，以及指导研究来实现这些目标。该研究计划制定和评估艾滋病毒预防干预措施，重点放在事件级别的饮酒和性伴侣选择上。该研究计划以三个目标为指导：(1)确定与无保护措施的性行为有关的最重要的事件级别酒精和伴侣特征；(2)确定导致高风险伴侣选择和事件级别酒精使用交叉的最有力的青少年风险因素；(3)制定和完成艾滋病毒预防干预的可行性试验，重点是改变青少年在饮酒时选择伴侣的情况。在K01的支持下，Staras博士将在酒精相关艾滋病毒预防干预措施的开发和评估方面获得实践经验，并将为在少数族裔青年中独立从事与酒精相关的艾滋病毒预防工作做好准备。

DESCRIPTION (provided by applicant): This application requests a NIAAA Mentored Research Scientist Development Award (K01) for Dr. Stephanie Staras to develop a research program of HIV prevention focused on the intersection of event-level alcohol use (i.e., alcohol use within 2 hours prior to sex) and sexual partner selection among minority adolescents. To accomplish the transition from infectious disease epidemiology to alcohol-related HIV prevention, Dr. Staras needs protected time to increase skills in developing and evaluating alcohol-related HIV preventive interventions among adolescents. Dr. Staras' career development goals are: (1) improve knowledge of theoretical frameworks for alcohol use and HIV transmission among adolescents; (2) strengthen research skills specifically needed to conduct alcohol-related HIV preventive interventions among minority adolescents; (3) increase understanding of ethical conduct of research in HIV prevention; and (4) begin an independent research program on HIV prevention focused on event-level alcohol use and partner selection. She will accomplish these goals through completion of directed studies with mentors, participation in coursework and workshops, and mentored research. The research plan develops and evaluates an HIV preventive intervention focused on event-level alcohol use and sexual partner selection. The research plan is guided by three aims: (1) identify the most important event-level alcohol and partner characteristics associated with unprotected sex; (2) identify the most potent adolescent risk factors for the intersection of risky partner selection and event-level alcohol use; (3) develop and complete a feasibility-trial of a HIV preventive intervention focusing on modifying adolescent partner selection when using alcohol. With support from this K01, Dr. Staras will gain hands-on experience in development and evaluation of alcohol-related HIV preventive interventions, and will be prepared well for an independent career in alcohol-related HIV prevention among minority youth.