HIV Risk Among Racially-Diverse, Minority Youth: Alcohol and Partner Selection

描述（由申请人提供）：本申请为Stephanie Staras博士申请NIAAA指导研究科学家发展奖（K01），以开发艾滋病毒预防研究项目，重点研究少数民族青少年事件水平酒精使用（即性行为前2小时内饮酒）和性伴侣选择的交叉。为了完成从传染病流行病学到酒精相关艾滋病毒预防的过渡，Staras博士需要有受保护的时间，以提高在青少年中制定和评估酒精相关艾滋病毒预防干预措施的技能。Staras博士的职业发展目标是：(1)提高对青少年酒精使用和艾滋病毒传播理论框架的认识；(2)加强在少数民族青少年中开展与酒精有关的艾滋病毒预防干预所需的专门研究技能；(3)提高对艾滋病毒预防研究伦理行为的理解；(4)开始一个独立的艾滋病毒预防研究项目，重点关注事件层面的酒精使用和伴侣选择。她将通过与导师一起完成定向学习、参与课程和研讨会以及指导研究来实现这些目标。该研究计划制定和评估艾滋病毒预防干预措施，重点关注事件级别的酒精使用和性伴侣选择。该研究计划以三个目标为指导：(1)确定与无保护性行为相关的最重要事件级别酒精和伴侣特征；(2)确定影响危险伴侣选择和事件水平酒精使用的最有效的青少年危险因素；(3)制定并完成一项以改变青少年饮酒时伴侣选择为重点的艾滋病毒预防干预的可行性试验。在K01的支持下，Staras博士将获得与酒精有关的艾滋病毒预防干预措施的开发和评估方面的实践经验，并为在少数民族青年中从事与酒精有关的艾滋病毒预防方面的独立职业做好准备。

DESCRIPTION (provided by applicant): This application requests a NIAAA Mentored Research Scientist Development Award (K01) for Dr. Stephanie Staras to develop a research program of HIV prevention focused on the intersection of event-level alcohol use (i.e., alcohol use within 2 hours prior to sex) and sexual partner selection among minority adolescents. To accomplish the transition from infectious disease epidemiology to alcohol-related HIV prevention, Dr. Staras needs protected time to increase skills in developing and evaluating alcohol-related HIV preventive interventions among adolescents. Dr. Staras' career development goals are: (1) improve knowledge of theoretical frameworks for alcohol use and HIV transmission among adolescents; (2) strengthen research skills specifically needed to conduct alcohol-related HIV preventive interventions among minority adolescents; (3) increase understanding of ethical conduct of research in HIV prevention; and (4) begin an independent research program on HIV prevention focused on event-level alcohol use and partner selection. She will accomplish these goals through completion of directed studies with mentors, participation in coursework and workshops, and mentored research. The research plan develops and evaluates an HIV preventive intervention focused on event-level alcohol use and sexual partner selection. The research plan is guided by three aims: (1) identify the most important event-level alcohol and partner characteristics associated with unprotected sex; (2) identify the most potent adolescent risk factors for the intersection of risky partner selection and event-level alcohol use; (3) develop and complete a feasibility-trial of a HIV preventive intervention focusing on modifying adolescent partner selection when using alcohol. With support from this K01, Dr. Staras will gain hands-on experience in development and evaluation of alcohol-related HIV preventive interventions, and will be prepared well for an independent career in alcohol-related HIV prevention among minority youth.