SYNERGY: The Dartmouth Center for clinical and Translational Science

本提案的总体目标是支持和加强我们的机构资助的达特茅斯中心 临床和转化科学，称为SYNERGY-临床和转化科学的综合之家 在达特茅斯学习科学达特茅斯在2010年推出了SYNERGY，这是一个建立在达特茅斯丰富的基础上的中心。 协作和学院文化，其跨学科的生命科学和卫生服务研究计划， 及其对加速将科学知识转化为实践和提高 人口健康。在过去的两年里，由于达特茅斯的资源，以及“中心地位”和 在达特茅斯领导人的授权下，SYNERGY采取了大胆的措施，开始改变 临床和转化研究机构的景观。我们提出了四个总体目标， 继续扩大我们对疾病生物学进行决定性科学研究的能力， 现有知识，以改变医学实践，从而改善当地，区域和 全国范围内。在未来五年，我们将：（1）加强协同，实现更大的跨学科和 方案研究的协同作用和效率，并促进机构文化，旨在促进 临床和转化科学;（2）确保SYNERGY研究人员可以轻松有效地访问 资源和服务，从而提高他们的生产力;（3）扩大和整合培训和职业生涯 发展计划，以建立研究重点和来自不同学科的学员之间的激情，他们的目标是 在临床和转化研究方面建立成功的职业生涯;（4）创建转化研究中心 人口研究是一种技术和分析资源，利用基于人口的价值， 从T1（基础研究）到T4（人口研究和卫生政策）的研究， 资源都为达特茅斯和国家CTSA财团。达特茅斯团结一致， SYNERGY将继续在当地、区域、 作为CTSA联盟的成员，在全国范围内，从而改善人口健康。 相关性（参见说明）： 达特茅斯在生命科学领域有着合作研究和跨学科教育的历史， 卫生服务研究，导致了达特茅斯的临床和转化中心的创建 科学，名为协同。正如本申请中所建议的，SYNERGY将被扩展以支持 有效和迅速地将科学发现转化为临床护理和改善人口健康。

The overarching goal of this proposal is to support and enhance our institutionally-funded Dartmouth Center for Clinical and Translational Science, called SYNERGY-an integrated home for clinical and translational science at Dartmouth. Dartmouth launched SYNERGY in 2010, a Center built on Dartmouth's richly collaborative and collegial culture, its interdisciplinary life sciences and health services research programs, and its commitment to accelerating the translation of scientific knowledge into practice and improved population health. Over the past two years, fueled by Dartmouth's resources, and by the "Center status" and authority given by Dartmouth's leaders, SYNERGY has taken bold steps to begin to transform the institution's landscape for clinical and translational research. We propose four overarching aims designed to continue to expand our ability to conduct decisive science on the biology of disease and to use new and existing knowledge to transform the practice of medicine and thus to improve health-locally, regionally and nationally. Over the next five years we will: (1) strengthen SYNERGY to achieve greater interdisciplinary and programmatic research synergism and efficiency and promote an institutional culture aimed at advancing clinical and translational science; (2) ensure that SYNERGY investigators can easily and efficiently access resources and services, and thus enhance their productivity; (3) expand and integrate training and career development programs to build research focus and passion among trainees from diverse disciplines who aim to build successful careers in clinical and translational research; and (4) create a Center for Translational Population Research , a technical and analytic resource that harnesses the value of population-based research across the spectrum from T l (basic research) to T4 (population research and health policy), as a resource both for Dartmouth and forthe national CTSA consortium. Dartmouth is united to ensure that SYNERGY will continue to transform the landscape for clinical and translational research locally, regionally, and-as a member of the CTSA consortium-nationally, and thus to improve population health. RELEVANCE (See instructions): Dartmouth has a history of collaborative research and interdisciplinary education in the life sciences and health services research that have led to the creation of Dartmouth's Center for Clinical and Translational Science, named SYNERGY. As proposed in this application, SYNERGY will be expanded to support the efficient and rapid translation of scientific findings into clinical care and improved population health.