SYNERGY: The Dartmouth Center for clinical and Translational Science

这项提案的首要目标是支持和加强我们由机构资助的达特茅斯中心 临床和翻译科学，称为协同-临床和翻译的综合之家 达特茅斯理工学院。达特茅斯在2010年推出了Synergy，这是一个建立在达特茅斯丰富的 协作和合作文化，其跨学科生命科学和卫生服务研究计划， 致力于加快将科学知识转化为实践，并改进 人口健康。在过去的两年里，在达特茅斯的资源和中心地位的推动下， 在达特茅斯领导人的授权下，Synergy已经采取了大胆的步骤，开始改变 临床和转化性研究的机构版图。我们提出了四个总体目标，旨在 继续扩大我们在疾病生物学方面进行决定性科学的能力，并使用新的和 现有知识，以改变医疗实践，从而改善健康--地方、区域和 全国范围内。未来五年，我们将：(1)加强协同，实现更大的跨学科和 方案研究、协同增效和效率，并促进旨在推动 临床和转化科学；(2)确保Synergy调查人员可以轻松高效地访问 资源和服务，从而提高他们的生产力；(3)扩大和整合培训和职业 发展计划，在来自不同学科的受训人员中培养研究重点和热情，他们的目标是 在临床和转化性研究领域建立成功的事业；以及(4)创建转化性研究中心 人口研究，一种技术和分析资源，利用基于人口的价值 研究范围从T L(基础研究)到T4(人口研究和卫生政策)，作为 达特茅斯和国家CTSA财团的资源。达特茅斯联合起来确保 Synergy将继续改变本地、地区性临床和转化性研究的格局， 作为CTSA财团的成员，它将在全国范围内开展活动，从而改善人口健康。 相关性(请参阅说明)： 达特茅斯大学在生命科学领域有着合作研究和跨学科教育的历史 卫生服务研究导致达特茅斯临床和翻译中心的创建 科学，名为协同效应。正如本申请中所建议的，Synergy将扩展为支持 高效、快速地将科学成果转化为临床护理和改善人口健康。

The overarching goal of this proposal is to support and enhance our institutionally-funded Dartmouth Center for Clinical and Translational Science, called SYNERGY-an integrated home for clinical and translational science at Dartmouth. Dartmouth launched SYNERGY in 2010, a Center built on Dartmouth's richly collaborative and collegial culture, its interdisciplinary life sciences and health services research programs, and its commitment to accelerating the translation of scientific knowledge into practice and improved population health. Over the past two years, fueled by Dartmouth's resources, and by the "Center status" and authority given by Dartmouth's leaders, SYNERGY has taken bold steps to begin to transform the institution's landscape for clinical and translational research. We propose four overarching aims designed to continue to expand our ability to conduct decisive science on the biology of disease and to use new and existing knowledge to transform the practice of medicine and thus to improve health-locally, regionally and nationally. Over the next five years we will: (1) strengthen SYNERGY to achieve greater interdisciplinary and programmatic research synergism and efficiency and promote an institutional culture aimed at advancing clinical and translational science; (2) ensure that SYNERGY investigators can easily and efficiently access resources and services, and thus enhance their productivity; (3) expand and integrate training and career development programs to build research focus and passion among trainees from diverse disciplines who aim to build successful careers in clinical and translational research; and (4) create a Center for Translational Population Research , a technical and analytic resource that harnesses the value of population-based research across the spectrum from T l (basic research) to T4 (population research and health policy), as a resource both for Dartmouth and for the national CTSA consortium. Dartmouth is united to ensure that SYNERGY will continue to transform the landscape for clinical and translational research locally, regionally, and-as a member of the CTSA consortium-nationally, and thus to improve population health. RELEVANCE (See instructions): Dartmouth has a history of collaborative research and interdisciplinary education in the life sciences and health services research that have led to the creation of Dartmouth's Center for Clinical and Translational Science, named SYNERGY. As proposed in this application, SYNERGY will be expanded to support the efficient and rapid translation of scientific findings into clinical care and improved population health.