Wits Non-communicable Disease Research Leadership Program

智慧非传染性疾病研究领导计划

• 批准号: 8513275
• 负责人: Nigel John Crowther
• 金额: $ 18.54万
• 依托单位: WITS HEALTH CONSORTIUM (PTY), LTD
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8513275
• 关键词: Address; Back; Basic Science; Birth; Cardiovascular Diseases; Clinical Sciences; Collaborations; Communicable Diseases; Communities; Developing Countries; Discipline; Disease; Doctor of Philosophy; Economics; Ensure; Environment; Epidemiology; Fostering; Generations; Genetic; Goals; Health; Health Policy; Heart; Human; Instruction; International; Intervention; Knowledge; Lead; Leadership; Life Style; Metabolic Diseases; Monitor; Nature; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Postdoctoral Fellow; Prevalence; Public Health; Recruitment Activity; Research; Research Personnel; Research Training; Rural; Scientist; Southern Africa; Training; Training Programs; Universities; Wit; burden of illness; community intervention; disability; effective intervention; feeding; genetic risk factor; health training; innovation; insight; intervention program; meetings; population health; programs; social; translational approach

The need for an integrated Research Training Program in non-communicable diseases in developing countries has arisen out of the need to understand the nature, extent and pace of the transition to the emerging diseases of lifestyle. The emphasis in training will be on cardiovascular and metabolic diseases (obesity and type 2 diabetes). The specific aim is to develop a Training Program and a group of well trained researchers at the Masters, PhD and post-doctoral levels that cut across disciplines and provide capacity to tackle the big questions. What is the prevalence of these diseases in southern Africa? How can we monitor and understand the underlying causes? What effective intervention programs could we develop? This Research Training Program will be embedded in a regional, national and international research framework. It is aligned with the Fogatry Goals of mobilizing the scientific community to address the shifting burden of disease and disability specifically in non-communicable diseases; it will develop human capacity to meet the challenges by providing sustainable training for health scientists; and it will foster a sustainable research environment in a developing country. It will be an integrated Program that will ensure knowledge generation and dissemination from the basic and clinical sciences to inform public health issues, including social and cultural considerstions. It is aimed at a translational approach that will feed back into population health policy. This training will be enabled through the integration and collaboration across several established research programs at the University of the Witwatersrand, including the Soweto Heart Study, the Agincourt Rural Facility and the Birth to Twenty Study, with the aim of understanding the epidemiology, the genetic risk factors, the mechanisms and opportunities for community intervention. Trainees recruited from developing countries will obtain a global insight into the causes and impact of non-communicable diseases on health. RELEVANCE (See instructions): Economic and cultural transition in developing nations is causing a shift to the increasing burden of non communicable diseases. A thorough understanding of the epidemiology and the social, genetic and environmental causes will lead to innovative and affordable interventions and treatments in developing countries.

在发展中国家需要一个综合的非传染性疾病研究培训方案 各国之所以需要了解向发展中国家过渡的性质、程度和速度， 新出现的生活方式疾病培训的重点将是心血管和代谢疾病 （肥胖和2型糖尿病）。具体目标是制定一个培训计划和一批训练有素的 研究人员在硕士，博士和博士后水平，跨越学科，并提供能力， 解决重大问题这些疾病在南部非洲的流行程度如何？我们如何监控 并了解其根本原因我们可以制定哪些有效的干预方案？这 研究培训计划将嵌入区域，国家和国际研究框架。它 与Fogatry的目标一致，即动员科学界解决 它将发展人的能力， 通过为健康科学家提供可持续的培训来应对挑战;它将促进可持续的研究 发展中国家的环境。这将是一个确保知识生成的综合计划 从基础科学和临床科学的传播，以告知公共卫生问题，包括社会和 文化关怀。它旨在采取一种转化方法，将反馈到人口健康 政策这项培训将通过几个已建立的机构之间的整合和合作来实现。 威特沃特斯兰德大学的研究项目，包括索韦托心脏研究，阿金库尔研究， 农村设施和出生到20岁的研究，目的是了解流行病学，遗传风险， 社区干预的因素、机制和机会。从发展中国家征聘的受训人员 各国将全面了解非传染性疾病的原因及其对健康的影响。 相关性（参见说明）： 发展中国家的经济和文化转型正在导致非物质文化遗产的负担日益加重， 传染病深入了解流行病学和社会，遗传和 环境原因将导致创新和负担得起的干预和治疗， 国家