Wits Non-communicable Disease Research Leadership Program

智慧非传染性疾病研究领导计划

• 批准号: 8310762
• 负责人: Nigel John Crowther
• 金额: $ 19.52万
• 依托单位: WITS HEALTH CONSORTIUM (PTY), LTD
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8310762
• 关键词: Address; Back; Basic Science; Birth; Cardiovascular Diseases; Clinical Sciences; Collaborations; Communicable Diseases; Communities; Developing Countries; Discipline; Disease; Doctor of Philosophy; Economics; Ensure; Environment; Epidemiology; Fostering; Generations; Genetic; Goals; Health; Health Policy; Heart; Human; Instruction; International; Intervention; Knowledge; Lead; Leadership; Life Style; Metabolic Diseases; Monitor; Nature; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Postdoctoral Fellow; Prevalence; Public Health; Recruitment Activity; Research; Research Personnel; Research Training; Rural; Scientist; Southern Africa; Training; Training Programs; Universities; Wit; burden of illness; community intervention; disability; effective intervention; feeding; genetic risk factor; health training; innovation; insight; intervention program; meetings; population health; programs; social; translational approach

The need for an integrated Research Training Program in non-communicable diseases in developing countries has arisen out of the need to understand the nature, extent and pace of the transition to the emerging diseases of lifestyle. The emphasis in training will be on cardiovascular and metabolic diseases (obesity and type 2 diabetes). The specific aim is to develop a Training Program and a group of well trained researchers at the Masters, PhD and post-doctoral levels that cut across disciplines and provide capacity to tackle the big questions. What is the prevalence of these diseases in southern Africa? How can we monitor and understand the underlying causes? What effective intervention programs could we develop? This Research Training Program will be embedded in a regional, national and international research framework. It is aligned with the Fogatry Goals of mobilizing the scientific community to address the shifting burden of disease and disability specifically in non-communicable diseases; it will develop human capacity to meet the challenges by providing sustainable training for health scientists; and it will foster a sustainable research environment in a developing country. It will be an integrated Program that will ensure knowledge generation and dissemination from the basic and clinical sciences to inform public health issues, including social and cultural considerstions. It is aimed at a translational approach that will feed back into population health policy. This training will be enabled through the integration and collaboration across several established research programs at the University of the Witwatersrand, including the Soweto Heart Study, the Agincourt Rural Facility and the Birth to Twenty Study, with the aim of understanding the epidemiology, the genetic risk factors, the mechanisms and opportunities for community intervention. Trainees recruited from developing countries will obtain a global insight into the causes and impact of non-communicable diseases on health. RELEVANCE (See instructions): Economic and cultural transition in developing nations is causing a shift to the increasing burden of non communicable diseases. A thorough understanding of the epidemiology and the social, genetic and environmental causes will lead to innovative and affordable interventions and treatments in developing countries.

发展中的非传染性疾病综合研究培训计划的必要性 国家之所以出现，是因为需要了解向 新出现的生活方式疾病。培训的重点将是心血管和代谢性疾病。 (肥胖和2型糖尿病)。具体目标是制定一个培训计划和一组训练有素的 硕士、博士和博士后水平的研究人员跨越学科并提供能力 解决大问题。这些疾病在南部非洲的流行情况如何？我们如何才能监控 并了解背后的原因？我们可以开发哪些有效的干预计划？这 研究培训计划将纳入区域、国家和国际研究框架。它 与Fogatry动员科学界解决不断变化的负担的目标保持一致 疾病和残疾，特别是在非传染性疾病方面；它将发展人的能力，以满足 通过为卫生科学家提供可持续的培训来应对挑战；它将促进可持续的研究 发展中国家的环境问题。这将是一个综合计划，将确保知识生成 并从基础和临床科学传播信息，以了解公共卫生问题，包括社会和 文化考量。它的目标是一种转化的方法，将反馈到人口健康 政策。此培训将通过跨多个已建立的 威特沃特斯兰德大学的研究项目，包括索韦托心脏研究，阿金库尔 农村设施和二十岁出生研究，目的是了解流行病学、遗传风险 社区干预的因素、机制和机会。从发展中招募的实习生 各国将在全球范围内深入了解非传染性疾病的原因和对健康的影响。 相关性(请参阅说明)： 发展中国家的经济和文化转型正在导致向日益沉重的非 传染病。对流行病学以及社会、遗传和疾病的全面了解 环境原因将导致创新和负担得起的干预和治疗 国家。