Wits Non-communicable Disease Research Leadership Program

智慧非传染性疾病研究领导计划

• 批准号: 8697168
• 负责人: Nigel John Crowther
• 金额: $ 18.93万
• 依托单位: WITS HEALTH CONSORTIUM (PTY), LTD
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8697168
• 关键词: Address; Back; Basic Science; Birth; Cardiovascular Diseases; Clinical Sciences; Collaborations; Communicable Diseases; Communities; Developing Countries; Discipline; Disease; Doctor of Philosophy; Economics; Ensure; Environment; Epidemiology; Fostering; Generations; Genetic; Goals; Health; Health Policy; Heart; Human; Instruction; International; Intervention; Knowledge; Lead; Leadership; Life Style; Metabolic Diseases; Monitor; Nature; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Postdoctoral Fellow; Prevalence; Public Health; Recruitment Activity; Research; Research Personnel; Research Training; Rural; Scientist; Southern Africa; Training; Training Programs; Universities; Wit; burden of illness; community intervention; disability; effective intervention; feeding; genetic risk factor; health training; innovation; insight; intervention program; meetings; population health; programs; social; translational approach

The need for an integrated Research Training Program in non-communicable diseases in developing countries has arisen out of the need to understand the nature, extent and pace of the transition to the emerging diseases of lifestyle. The emphasis in training will be on cardiovascular and metabolic diseases (obesity and type 2 diabetes). The specific aim is to develop a Training Program and a group of well trained researchers at the Masters, PhD and post-doctoral levels that cut across disciplines and provide capacity to tackle the big questions. What is the prevalence of these diseases in southern Africa? How can we monitor and understand the underlying causes? What effective intervention programs could we develop? This Research Training Program will be embedded in a regional, national and international research framework. It is aligned with the Fogatry Goals of mobilizing the scientific community to address the shifting burden of disease and disability specifically in non-communicable diseases; it will develop human capacity to meet the challenges by providing sustainable training for health scientists; and it will foster a sustainable research environment in a developing country. It will be an integrated Program that will ensure knowledge generation and dissemination from the basic and clinical sciences to inform public health issues, including social and cultural considerstions. It is aimed at a translational approach that will feed back into population health policy. This training will be enabled through the integration and collaboration across several established research programs at the University of the Witwatersrand, including the Soweto Heart Study, the Agincourt Rural Facility and the Birth to Twenty Study, with the aim of understanding the epidemiology, the genetic risk factors, the mechanisms and opportunities for community intervention. Trainees recruited from developing countries will obtain a global insight into the causes and impact of non-communicable diseases on health. RELEVANCE (See instructions): Economic and cultural transition in developing nations is causing a shift to the increasing burden of non communicable diseases. A thorough understanding of the epidemiology and the social, genetic and environmental causes will lead to innovative and affordable interventions and treatments in developing countries.

发展中国家非传染性疾病综合研究培训方案的必要性

项目成果

The impact of dietary habits and nutritional deficiencies in urban African patients living with heart failure in Soweto, South Africa--a review.

• DOI: 10.2174/1871530311313010014
• 发表时间: 2013-02
• 期刊: Endocrine, metabolic & immune disorders drug targets
• 作者: S. Pretorius

Relationships between structure, process and outcome to assess quality of integrated chronic disease management in a rural South African setting: applying a structural equation model.

• DOI: 10.1186/s12913-017-2177-4
• 发表时间: 2017-03-23
• 期刊: BMC health services research
• 影响因子: 2.8
• 作者: Ameh S;Gómez-Olivé FX;Kahn K;Tollman SM;Klipstein-Grobusch K
• 通讯作者: Klipstein-Grobusch K

Quality of integrated chronic disease care in rural South Africa: user and provider perspectives.

• DOI: 10.1093/heapol/czw118
• 发表时间: 2017-03-01
• 期刊: Health policy and planning
• 影响因子: 3.2
• 作者: Ameh S;Klipstein-Grobusch K;D'ambruoso L;Kahn K;Tollman SM;Gómez-Olivé FX
• 通讯作者: Gómez-Olivé FX

Economic burden of stroke in a rural South African setting.

• DOI: 10.1016/j.ensci.2016.01.001
• 发表时间: 2016-06-01
• 期刊: eNeurologicalSci
• 作者: Maredza M;Chola L
• 通讯作者: Chola L

The effect of lifestyle interventions on maternal body composition during pregnancy in developing countries: a systematic review.

生活方式干预对发展中国家怀孕期间母亲身体成分的影响：系统评价。

• DOI: 10.5830/cvja-2017-003
• 发表时间: 2017
• 期刊: Cardiovascular journal of Africa
• 影响因子: 0.7
• 作者: Watson,EstelleD;Macaulay,Shelley;Lamont,Kim;Gradidge,PhilippeJ-L;Pretorius,Sandra;Crowther,NigelJ;Libhaber,Elena
• 通讯作者: Libhaber,Elena