2013 Nitric Oxide Gordon Research Conference

2013年一氧化氮戈登研究会议

• 批准号: 8526701
• 负责人: HARRY ISCHIROPOULOS
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-15 至 2014-02-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8526701
• 关键词: Academia; Address; Area; Award; Basic Science; Biochemistry; Biological; Biological Availability; Biology; Blood Vessels; Cardiovascular Diseases; Cardiovascular system; Cell Survival; Cell physiology; Cellular biology; Chemistry; Clinical Pharmacology; Clinical Sciences; Complex; Development; Dietary Intervention; Disease; Equilibrium; Fatty Acids; Fees; Female; Fostering; Functional disorder; Funding; Generations; Goals; Government; Health; Immune system; Individual; Industry; Knowledge; Metabolic Diseases; Mitochondria; Molecular Biology; Nervous system structure; Nitric Oxide; Nitrites; Nitrogen Oxides; Nutritional; Organ; Paper; Participant; Pathway interactions; Pharmacology; Physiological; Physiology; Play; Postdoctoral Fellow; Process; Property; Publishing; Recording of previous events; Recruitment Activity; Regulation; Research; Research Personnel; Respiration; Role; S-Nitrosothiols; Science; Scientist; Signal Pathway; Signal Transduction; Signaling Molecule; Structure-Activity Relationship; Systems Biology; Therapeutic; Therapeutic Agents; Translational Research; Travel; Underrepresented Minority; Woman; Work; abstracting; base; cardiovascular disorder prevention; cost; design; graduate student; insight; interest; lectures; meetings; multidisciplinary; novel; planetary Atmosphere; posters; prevent; programs; public health relevance; response; symposium

DESCRIPTION (provided by applicant): GRC NO 2013 The Gordon Research Conference on Nitric Oxide (NO) is designed to provide biologists, chemists, clinicians and other scientists with state-of-the-art knowledge on the basic structure/function relationships of NO generating systems, and the biology of NO as a signaling and effector molecule in physiology and pathophysiology. A long-term goal is to use this knowledge in development of novel NO based therapeutics in particular for treatment and prevention of cardiovascular disease. This research conference is held every two years and the next conference will take place at the Ventura Beach Marriott in Ventura, CA on Feb 17-22, 2013. Approximately 160 participants from academia, government and industry are expected to attend. Funds are requested to support conference registration and travel costs fees for participants (i.e. speakers/discussion leaders and for exceptional graduate students/post-doctoral candidates and other junior scientists working in the field of NO biology). The speakers have been selected to address unresolved questions and cover emerging new areas in the field and to balance the program with senior and junior investigators. In a specific effort to promote and showcase the work of younger scientists, 12 highly talented junior researchers (5 females) have been invited to give full talks. Senior leaders in the field will chair these sessions. Sessions will focus on novel insights on the regulation of NO formation and signaling. Chemically related nitrogen oxide species with signaling properties including S-nitrosothiols, nitrite and nitro fatty acids will be discussed in depth. In addition, therapeutic avenues will be covered with an emphasis on how enhancement of NO bioavailability via newly described principles might be used to treat and prevent cardiovascular and metabolic disease. 1998 Nobel laureate Louis J Ignarro has kindly agreed to present the Keynote Lecture. In addition, there are two prominently featured and moderated poster sessions selected from abstracts submitted to the meeting, a special session on "Current Controversies and Late-Breaking Findings" and a "Hot Topics" session that encourages last-minute submissions of exciting findings from new or established investigators culminating in awards given to several of the junior investigators. The main strength of this meeting is the opportunity for cross-disciplinary interactions in a highly focused, yet informal intellectually stimulating atmosphere. The Gordon Conference on NO plays an essential role in providing guidance and exploring new vistas in this important field of basic and translational research.

描述（由申请人提供）：GRC NO 2013 戈登一氧化氮 (NO) 研究会议旨在为生物学家、化学家、临床医生和其他科学家提供 关于 NO 生成系统的基本结构/功能关系以及 NO 作为生理学和病理生理学中信号分子和效应分子的生物学的最新知识。长期目标是利用这些知识开发基于 NO 的新型疗法，特别是用于治疗和预防心血管疾病。该研究会议每两年举行一次，下一次会议将于 2013 年 2 月 17 日至 22 日在加利福尼亚州文图拉的文图拉海滩万豪酒店举行。预计将有来自学术界、政府和行业的约 160 名与会者参加。需要资金来支持参与者（即演讲者/讨论领导者以及优秀研究生/博士后候选人和其他在 NO 生物学领域工作的初级科学家）的会议注册费和差旅费。发言人的选择是为了解决未解决的问题并涵盖该领域新兴的新领域，并平衡高级和初级研究人员的计划。为了促进和展示年轻科学家的工作，12 位才华横溢的初级研究人员（5 名女性）应邀进行了全面演讲。 该领域的高级领导人将主持这些会议。会议将重点讨论有关 NO 形成和信号传导的调节。将深入讨论具有信号特性的化学相关氮氧化物物质，包括 S-亚硝基硫醇、亚硝酸盐和硝基脂肪酸。此外，还将讨论治疗途径，重点是如何通过新描述的原理增强一氧化氮的生物利用度来治疗和预防心血管和代谢疾病。 1998 年诺贝尔奖获得者路易斯·J·伊格纳罗 (Louis J Ignarro) 欣然同意发表主题演讲。此外，还有两个从提交给会议的摘要中选出的突出特色和主持的海报会议，一个关于“当前争议和最新发现”的特别会议，以及一个“热门话题”会议，鼓励新的或成熟的研究人员在最后一刻提交令人兴奋的发现，最终为几位初级研究人员颁发奖项。这次会议的主要优势是在高度集中但非正式的智力刺激氛围中提供跨学科互动的机会。戈登NO会议在为基础和转化研究这一重要领域提供指导和探索新前景方面发挥着至关重要的作用。