SCALE: Small Changes and Lasting Effects

规模：微小的变化和持久的影响

• 批准号: 8518444
• 负责人: MARY E CHARLSON
• 金额: $ 117.54万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-25 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8518444
• 关键词: Adult; Affect; Basic Science; Behavior Therapy; Behavioral; Body Weight Changes; Body Weight decreased; Buffers; Characteristics; Chronic; Clinic; Clinical Research; Collaborations; Color; Communities; Coupled; Diabetes Mellitus; Eating; Eating Behavior; Educational Intervention; Effectiveness; Effectiveness of Interventions; Epidemic; Evaluation; Family; Fatty acid glycerol esters; Focus Groups; General Population; Goals; Health; Health behavior; Hospitals; Individual; Informatics; Intake; Intervention; Laboratory Study; Latino; Life; Life Style; Measures; Mediating; Medical Sociology; Medical center; Medicine; Morbidity - disease rate; New York City; Obesity; Outcome; Overweight; Participant; Patient Education; Patients; Phase; Physical activity; Primary Health Care; Psychology; Public Health; Pulmonary Heart Disease; Qualitative Research; Renaissance; Research Infrastructure; Sampling; Scientist; Self Efficacy; Social Network; Social Sciences; Stress; Testing; Translating; Translational Research; Treatment Efficacy; Weight; Woman; Work; base; behavior change; behavioral/social science; clinical epidemiology; design; experience; faith-based intervention; field study; health disparity; hypertensive heart disease; innovation; intervention effect; motivated behavior; nutrition; prevent; primary outcome; randomized trial; secondary outcome; statistics; success; theories; therapy design; therapy development; weight maintenance

The goal of the Cornell Center for Behavioral Intervention Development is to translate basic behavioral and social science discoveries into effective behavioral interventions that reduce obesity in Black and Latino communities. To achieve this goal, we have brought together an accomplished interdisciplinary team of scientists who have expertise in conducting translational research in communities of color. Primary aim: Among overweight or obese Black or Latino adults who live in Harlem or the South Bronx, the objectives are: 1) to establish an infrastructure for translating basic and social science discoveries to develop effective behavioral interventions targeted at preventing and treating obesity; and 2) to further develop and refine mindful eating interventions in order to achieve a >7% within-patient reduction in weight through small sustained changes in eating behavior coupled with sustained increases in lifestyle physical activity. Phase I Defining the intervention We will further develop and refine our mindful eating intervention through focus groups in three different settings: individual, family and faith-based. Then small pilot tests of the mindful eating intervention with and without a positive affect/self affirmation intervention will be done. Phase II Characterizing the intervention effects: In three parallel 'proof of concept' randomized trials, the refined mindful eating intervention will be compared in each setting to a education intervention. In these trials, the mindful eating intervention will be coupled with a positive affect/self affirmation intervention which our recently completed randomized trial has shown to significantly increase physical activity in overweight/obese patients. At 12 months, the primary outcome will be % change in weight. Phase III Assessing feasibility and refining the intervention: The phase II proof of concept trials will be analyzed and the intervention will be refined. A formative study of those who fared the best and the worst in each of the settings will be done. A large scale trial will be planned to test the effectiveness of the optimized intervention. Long term objective: The Center will identify which mindful eating intervention in which setting (individual, family or faith-based) coupled with positive affect/self affirmation to increase lifestyle physical activity have the potential to be more effective in creating sustainable eating and physical activity behavior change and weight loss in a scalable way in Black and Latino communities.

康奈尔行为干预发展中心的目标是将基本的行为干预转化为 和社会科学的发现转化为有效的行为干预，减少黑人和拉丁美洲人的肥胖 社区.为了实现这一目标，我们汇集了一个跨学科的团队， 在有色人种社区进行转化研究方面具有专业知识的科学家。 主要目的：在超重或肥胖的黑人或拉丁美洲成年人谁住在哈莱姆或南布朗克斯， 目标是：1）建立基础设施，将基础科学和社会科学发现转化为发展 有效的行为干预措施，旨在预防和治疗肥胖症; 2）进一步发展和 改善正念饮食干预，通过小剂量的饮食干预， 饮食行为的持续变化，加上生活方式的身体活动的持续增加。 第一阶段界定干预措施我们将进一步发展和完善我们的正念饮食干预措施， 三种不同背景下的焦点小组：个人、家庭和信仰。然后进行小型试点测试， 将进行有或没有积极影响/自我肯定干预的正念饮食干预。 第二阶段描述干预效果：在三个平行的“概念验证”随机试验中， 在每种情况下，将精细的正念饮食干预与教育干预进行比较。在这些 试验中，正念饮食干预将与积极的情感/自我肯定干预相结合， 我们最近完成的随机试验表明， 超重/肥胖患者。12个月时，主要结局为体重变化%。 第三阶段评估可行性并完善干预措施：第二阶段的概念验证试验将 分析并完善干预措施。一项对那些表现最好和最差的人的形成性研究， 将完成每个设置。将计划进行大规模试验，以测试优化的 干预 长期目标：该中心将确定在何种环境下（个人， 家庭或信仰为基础）加上积极的影响/自我肯定，以增加生活方式的身体活动， 更有效地创造可持续饮食和体育活动行为改变的潜力， 在黑人和拉丁裔社区以可扩展的方式减肥。

项目成果

The Relationship between Social Network Body Size and the Body Size Norms of Black and Hispanic Adults.

社交网络体型与黑人和西班牙裔成年人体型标准之间的关系。

• DOI: 10.1016/j.pmedr.2015.10.014
• 发表时间: 2015
• 期刊: Preventive medicine reports
• 影响因子: 2.8
• 作者: Winston,Ginger;Phillips,Erica;Wethington,Elaine;Wells,Martin;Devine,CarolM;Peterson,Janey;Wansink,Brian;Ramos,Rosio;Charlson,Mary
• 通讯作者: Charlson,Mary

Innovative approaches to weight loss in a high-risk population: The small changes and lasting effects (SCALE) trial.

高危人群减肥的创新方法：微小变化和持久影响（SCALE）试验。

• DOI: 10.1002/oby.21780
• 发表时间: 2017
• 期刊: Obesity (Silver Spring, Md.)
• 作者: Phillips,EricaG;Wells,MartinT;Winston,Ginger;Ramos,Rosio;Devine,CarolM;Wethington,Elaine;Peterson,JaneyC;Wansink,Brian;Charlson,Mary
• 通讯作者: Charlson,Mary