Institutional Training Grant in the Genomic Sciences

描述（由申请人提供）：基因组科学培训计划（GSTP）正在培养新一代的基因组科学家，他们的优势跨越多个学科。我们提出的培训机会和环境将使我们的学员能够开发和应用新的工具，这些工具来自技术进步，这些技术进步是由尖端的统计和计算方法提供信息的，这些方法可以使多样化和大型数据集功能化。生物学和医学研究的新基因组方法要求科学家在几个领域中以有效的方式掌握知识和技能，从而产生新的见解或发明。因此，全面贸易优惠制通过将来自多个领域的调查方法进行教学式的交织，（生物学、遗传学、物理科学、工程学、计算机科学和统计学），这些学科被单独勾画出来，以补充受训者的核心学科重点，但它是建立在基因组科学的成就和知识之上的。鉴于威斯康星州大学令人难以置信的丰富的科学和工程广度，GSTP能够招募优秀的学员谁大大先进的质谱，微阵列技术，计算和生物设备，同时探索新的应用程序，利用这些优势，为尖端的研究到蛋白质组学，转录，代谢组学和基因组生物学。这样的成就已经催生了一个重要的基因组学社区在我们的校园通过学员和培训师的网络成为突破性的合作达到跨部门，中心和其他培训计划的中心枢纽的建立。我们建议更新这一计划，我们继续这一重点，增加重点的全球优惠制的方案评估，增加培训，开发方法，分析和解释大型数据集，并促进临床应用。我们要求每年培训资金：10名博士前（1-3年），4名博士后（1 -3年）和2名短期（0.25年）学员;我们将寻求最近的本科和研究生学位的学员。

DESCRIPTION (provided by applicant): The Genomic Sciences Training Program (GSTP) is training the new generation of genomic scientists with strengths spanning across multiple disciplines. The training opportunities and environment we propose will enable our trainees to develop and apply new tools, derived from technological advances that are informed by cutting-edge statistical and computational approaches that functionalize diverse and large datasets. The new genomic approaches to biological and medical investigation demand scientists who are knowledgeable and skilled across several fields in effective ways that potentate new insights or inventions. Accordingly, the emergence of new tools allowing for the creation and interpretation of large-scale experimental efforts is what GSTP has focused on by the didactical interweaving of investigative approaches drawn from multiple fields (biology, genetics, physical sciences, engineering, computer science, and statistics) that were individually contoured for complementing a trainee's core disciplinary focus, yet built upon achievement and knowledge within the genomic sciences. Given the incredibly rich scientific and engineering breadth of the University of Wisconsin, GSTP was able to recruit outstanding trainees who greatly advanced mass spectroscopy, microarray technologies, computation, and bio-devices, while exploring new applications leveraging these advantages for cutting-edge investigation into proteomics, transcription, metabolomics, and genome biology. Such achievement has spawned the establishment of a significant genomics community on our campus through networking of trainees and trainers to become central hubs for groundbreaking collaborations reaching across departments, centers, and other training programs. We propose for the renewal of this program that we continue this focus with added emphasis on programmatic evaluation of GSTP, increased training in developing methods for analyzing and interpreting large datasets, and fostering of clinical applications. We request funding for training on a yearly basis: 10 predoctoral (1-3 yrs), 4 postdoctoral (1-3 yrs), and 2 short-term (0.25 yr) trainees; we will seek trainees with recent undergraduate and graduate degrees.