Institutional Training in the Genomic Sciences

基因组科学机构培训

• 批准号: 9390143
• 负责人: DAVID C. SCHWARTZ
• 金额: $ 0.78万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-12-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9390143
• 关键词: Genomics; Science; Training

DESCRIPTION (provided by applicant): The Genomic Sciences Training Program (GSTP) is training the new generation of genomic scientists with strengths spanning across multiple disciplines. The training opportunities and environment we propose will enable our trainees to develop and apply new tools, derived from technological advances that are informed by cutting-edge statistical and computational approaches that functionalize diverse and large datasets. The new genomic approaches to biological and medical investigation demand scientists who are knowledgeable and skilled across several fields in effective ways that potentate new insights or inventions. Accordingly, the emergence of new tools allowing for the creation and interpretation of large-scale experimental efforts is what GSTP has focused on by the didactical interweaving of investigative approaches drawn from multiple fields (biology, genetics, physical sciences, engineering, computer science, and statistics) that were individually contoured for complementing a trainee's core disciplinary focus, yet built upon achievement and knowledge within the genomic sciences. Given the incredibly rich scientific and engineering breadth of the University of Wisconsin, GSTP was able to recruit outstanding trainees who greatly advanced mass spectroscopy, microarray technologies, computation, and bio-devices, while exploring new applications leveraging these advantages for cutting-edge investigation into proteomics, transcription, metabolomics, and genome biology. Such achievement has spawned the establishment of a significant genomics community on our campus through networking of trainees and trainers to become central hubs for groundbreaking collaborations reaching across departments, centers, and other training programs. We propose for the renewal of this program that we continue this focus with added emphasis on programmatic evaluation of GSTP, increased training in developing methods for analyzing and interpreting large datasets, and fostering of clinical applications. We request funding for training on a yearly basis: 10 predoctoral (1-3 yrs), 4 postdoctoral (1-3 yrs), and 2 short-term (0.25 yr) trainees; we will seek trainees with recent undergraduate and graduate degrees.

描述（由申请人提供）：基因组科学培训计划（GSTP）正在培训具有跨多个学科优势的新一代基因组科学家。我们提出的培训机会和环境将使我们的学员能够开发和应用新工具，这些工具源自技术进步，这些技术进步是通过尖端统计和计算方法实现的，这些方法可以实现多样化和大型数据集的功能。生物和医学研究的新基因组方法需要科学家在多个领域拥有知识和技能，以有效的方式增强新的见解或发明。因此，允许创建和解释大规模实验工作的新工具的出现是 GSTP 关注的重点，通过将来自多个领域（生物学、遗传学、物理科学、工程学、计算机科学和统计学）的研究方法进行教学交织，这些研究方法分别针对学员的核心学科重点进行了补充，但又建立在基因组科学领域的成就和知识的基础上。鉴于威斯康星大学极其丰富的科学和工程广度，GSTP 能够招募到极大地推进了质谱、微阵列技术、计算和生物设备的优秀学员，同时探索利用这些优势进行蛋白质组学、转录、代谢组学和基因组生物学前沿研究的新应用。这些成就促使我们校园内建立了一个重要的基因组学社区，通过学员和培训师的网络，成为跨部门、中心和其他培训项目进行突破性合作的中心枢纽。我们建议更新该计划，继续重点关注 GSTP 的计划评估、加强开发分析和解释大型数据集的方法以及促进临床应用的培训。我们每年请求培训资金：10名博士前（1-3年）、4名博士后（1-3年）和2名短期（0.25年）学员；我们将寻找具有近期本科和研究生学位的学员。