Inhibiting the Renin-Angiotensin System to treat wasting in cancer

抑制肾素-血管紧张素系统治疗癌症消耗

• 批准号: nhmrc : 1023178
• 负责人: Dr Kate Murphy
• 金额: $ 30.2万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/inhibiting-renin-angiotensin-wasting-cancer/110251
• 关键词: Inhibiting; Renin; Angiotensin; System; treat

Cancer cachexia is a devastating disease characterised by skeletal muscle wasting and weakness. It impairs patient quality of life and accounts for >20% of cancer-related deaths. My work aims to identify factors contributing to the development of cancer cachexia. This insight will then enable me to test potential strategies to prevent the wasting seen in cancer patients to improve their quality of life and to reduce mortality.

癌症恶病质是一种毁灭性的疾病，其特征是骨骼肌萎缩和虚弱。它损害了患者的生活质量，占癌症相关死亡人数的20%。我的工作旨在找出导致癌症恶病质发展的因素。然后，这种洞察力将使我能够测试潜在的策略，以防止癌症患者出现的浪费，以提高他们的生活质量，降低死亡率。